Decitabine

DNA methyltransferase (cytosine-5) 1 ; Mus musculus







43 Article(s)
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1 34801707 Etoposide-induced protein 2.4 ameliorates high glucose-induced epithelial-mesenchymal transition by activating adenosine monophosphate-activated protein kinase pathway in renal tubular cells. 2022 Jan 2
2 34976218 5-aza-2'-deoxycytidine potentiates anti-tumor immunity in colorectal peritoneal metastasis by modulating ABC A9-mediated cholesterol accumulation in macrophages. 2022 4
3 32935231 Prenatal Stress Leads to the Altered Maturation of Corticostriatal Synaptic Plasticity and Related Behavioral Impairments Through Epigenetic Modifications of Dopamine D2 Receptor in Mice. 2021 Jan 1
4 34503994 5-Aza-4'-thio-2'-deoxycytidine, a New Orally Bioavailable Nontoxic "Best-in-Class": DNA Methyltransferase 1-Depleting Agent in Clinical Development. 2021 Nov 4
5 34830365 Histone Methyltransferases SUV39H1 and G9a and DNA Methyltransferase DNMT1 in Penumbra Neurons and Astrocytes after Photothrombotic Stroke. 2021 Nov 19 1
6 34906184 The DNMT1 inhibitor GSK-3484862 mediates global demethylation in murine embryonic stem cells. 2021 Dec 15 1
7 32211762 Epigenetic Modifications of GABAergic Interneurons Contribute to Deficits in Adult Hippocampus Neurogenesis and Depression-Like Behavior in Prenatally Stressed Mice. 2020 Apr 23 1
8 32554751 Autocrine IL6-Mediated Activation of the STAT3-DNMT Axis Silences the TNFα-RIP1 Necroptosis Pathway to Sustain Survival and Accumulation of Myeloid-Derived Suppressor Cells. 2020 Aug 1 2
9 30586565 Dynamic decreased expression and hypermethylation of secreted frizzled-related protein 1 and 4 over the course of pulmonary fibrosis in mice. 2019 Feb 1 1
10 31239244 PPARγ preservation via promoter demethylation alleviates osteoarthritis in mice. 2019 Oct 1
11 31240997 DNA methyltransferase inhibition reduces inflammation-induced colon tumorigenesis. 2019 Dec 4
12 31534549 Prostaglandin E2 induces DNA hypermethylation in gastric cancer in vitro and in vivo. 2019 1
13 28318634 DNA methyltransferase 1 may be a therapy target for attenuating diabetic nephropathy and podocyte injury. 2017 Jul 1
14 28433417 Mechanistic insights into epigenetic modulation of ethanol consumption. 2017 May 1
15 28750405 Untargeted DNA-Demethylation Therapy Neither Prevents Nor Attenuates Ischemia-Reperfusion-Induced Renal Fibrosis. 2017 3
16 27665473 Effects of 5-Aza-2'-deoxycytidine on expression of PP1γ in learning and memory. 2016 Dec 1
17 25096638 Genome-wide demethylation by 5-aza-2'-deoxycytidine alters the cell fate of stem/progenitor cells. 2015 Feb 2
18 26085088 The DNA Methyltransferase DNMT1 and Tyrosine-Protein Kinase KIT Cooperatively Promote Resistance to 5-Aza-2'-deoxycytidine (Decitabine) and Midostaurin (PKC412) in Lung Cancer Cells. 2015 Jul 24 6
19 26333597 TGF-β1 epigenetically modifies Thy-1 expression in primary lung fibroblasts. 2015 Nov 1 2
20 24525423 Learning induced epigenetic modifications in the ventral striatum are necessary for long-term memory. 2014 May 15 1
21 24739303 Epigenetic regulation of aortic remodeling in hyperhomocysteinemia. 2014 Aug 3
22 24944101 'Default' generated neonatal regulatory T cells are hypomethylated at conserved non-coding sequence 2 and promote long-term cardiac allograft survival. 2014 Dec 2
23 23306545 Epigenetic regulation of miR-17~92 contributes to the pathogenesis of pulmonary fibrosis. 2013 Feb 15 1
24 23809695 Specific inhibition of one DNMT1-including complex influences tumor initiation and progression. 2013 Jun 28 1
25 23814491 Prostaglandin E2 Promotes UV radiation-induced immune suppression through DNA hypermethylation. 2013 Jul 4
26 23926181 Aldosterone reprograms promoter methylation to regulate αENaC transcription in the collecting duct. 2013 Oct 1 2
27 24038143 The E2F1/DNMT1 axis is associated with the development of AR negative castration resistant prostate cancer. 2013 Dec 1
28 21796622 Epigenetic regulation by decitabine of melanoma differentiation in vitro and in vivo. 2012 Jul 1 4
29 22160381 Effects of tetrahydrouridine on pharmacokinetics and pharmacodynamics of oral decitabine. 2012 Feb 2 7
30 22349820 5-aza-2'-deoxycytidine-induced genome rearrangements are mediated by DNMT1. 2012 Dec 13 6
31 22893792 Novel Insights into the Molecular Mechanism of Action of DNA Hypomethylating Agents: Role of Protein Kinase C δ in Decitabine-Induced Degradation of DNA Methyltransferase 1. 2012 Jan 1
32 21828137 DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation. 2011 Sep 29 1
33 19996551 Resistance to 5-aza-2'-deoxycytidine in genic regions compared to non-genic repetitive sequences. 2010 Feb 3
34 20062804 Nrf2 expression is regulated by epigenetic mechanisms in prostate cancer of TRAMP mice. 2010 Jan 5 2
35 20348135 Targeting of 5-aza-2'-deoxycytidine residues by chromatin-associated DNMT1 induces proteasomal degradation of the free enzyme. 2010 Jul 5
36 20599948 Cell cycle-dependent accumulation of histone H3.3 and euchromatic histone modifications in pericentromeric heterochromatin in response to a decrease in DNA methylation levels. 2010 Oct 15 4
37 19222872 5-AZA-2'-deoxycytidine (5-AZA-CdR) leads to down-regulation of Dnmt1o and gene expression in preimplantation mouse embryos. 2009 May 1
38 16568088 Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasis. 2006 Aug 17 2
39 17108113 Epigenetic regulation of tumor endothelial cell anergy: silencing of intercellular adhesion molecule-1 by histone modifications. 2006 Nov 15 1
40 14581508 5-aza-2'-deoxycytidine induces alterations in murine spermatogenesis and pregnancy outcome. 2003 Nov-Dec 2
41 14612500 Inhibition of DNA methylation and histone deacetylation prevents murine lung cancer. 2003 Nov 1 1
42 10777781 DNA methyltransferase contributes to delayed ischemic brain injury. 2000 May 1 1
43 10447688 Feedback regulation of DNA methyltransferase gene expression by methylation. 1999 Aug 1