Dipeptides

nucleotide binding oligomerization domain containing 2 ; Homo sapiens







66 Article(s)
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1 34725731 NOD2 and reproduction-associated NOD-like receptors have been lost during the evolution of pangolins. 2022 Apr 1
2 34951523 Synthesis and Evaluation of Diverse N-Substituted Disaccharide Dipeptides for Human NOD2 Stimulation Activity. 2022 Feb 14 1
3 35584401 Membrane targeting enhances muramyl dipeptide binding to NOD2 and Arf6-GTPase in mammalian cells. 2022 Jun 8 1
4 33245410 NOD2 induces VCAM-1 and ET-1 gene expression via NF-κB in human umbilical vein endothelial cells with muramyl dipeptide stimulation. 2021 Sep 1
5 33602264 A novel mutation in early-onset sarcoidosis/Blau syndrome: an association with Propionibacterium acnes. 2021 Feb 18 1
6 34860029 Structural Elucidation of Inter-CARD Interfaces involved in NOD2 Tandem CARD Association and RIP2 Recognition. 2021 Dec 16 2
7 34943999 The Interleukins Orchestrate Mucosal Immune Responses to Salmonella Infection in the Intestine. 2021 Dec 10 1
8 29501442 Analysis of Genes Associated With Monogenic Primary Immunodeficiency Identifies Rare Variants in XIAP in Patients With Crohn's Disease. 2018 Jun 1
9 26953272 Impaired antibacterial autophagy links granulomatous intestinal inflammation in Niemann-Pick disease type C1 and XIAP deficiency with NOD2 variants in Crohn's disease. 2017 Jun 1
10 27791288 Enhancement of Muramyl Dipeptide-Dependent NOD2 Activity by a Self-Derived Peptide. 2017 May 1
11 28221793 Correction to Antagonizing NOD2 Signaling with Conjugates of Paclitaxel and Muramyl Dipeptide Derivatives Sensitizes Paclitaxel Therapy and Significantly Prevents Tumor Metastasis. 2017 Mar 9 1
12 28365256 Corrigendum to "Epicutaneous immunization with protein antigen TNP-Ig and NOD2 ligand muramyl dipeptide (MDP) reverses skin-induced suppression of contact hypersensitivity" [Pharmacol. Rep. 66 (2014) 137-142]. 2017 Jun 1
13 28708377 Membrane Association Dictates Ligand Specificity for the Innate Immune Receptor NOD2. 2017 Aug 18 1
14 29263823 Relation between NOD2 genotype and changes in innate signaling in Crohn's disease on mRNA and miRNA levels. 2017 4
15 27077833 Aberrant Expression of Bacterial Pattern Recognition Receptor NOD2 of Basophils and Microbicidal Peptides in Atopic Dermatitis. 2016 Apr 11 1
16 27297389 Human NOD2 Recognizes Structurally Unique Muramyl Dipeptides from Mycobacterium leprae. 2016 Sep 1
17 27374331 Hexokinase Is an Innate Immune Receptor for the Detection of Bacterial Peptidoglycan. 2016 Jul 28 1
18 24297055 NOD2 expression is regulated by microRNAs in colonic epithelial HCT116 cells. 2014 Jan 2
19 24695226 Endosomes are specialized platforms for bacterial sensing and NOD2 signalling. 2014 May 8 2
20 25183734 Recognition of Streptococcus pneumoniae and muramyl dipeptide by NOD2 results in potent induction of MMP-9, which can be controlled by lipopolysaccharide stimulation. 2014 Dec 1
21 25520185 Insights into the molecular basis of the NOD2 signalling pathway. 2014 Dec 1
22 22890731 Peptidoglycan and muramyl dipeptide from Staphylococcus aureus induce the expression of VEGF-A in human limbal fibroblasts with the participation of TLR2-NFκB and NOD2-EGFR. 2013 Jan 1
23 23275943 Muramyl dipeptide responsive pathways in Crohn's disease: from NOD2 and beyond. 2013 Sep 1
24 23437331 p62/SQSTM1 enhances NOD2-mediated signaling and cytokine production through stabilizing NOD2 oligomerization. 2013 1
25 23678609 [The present and the prospect of study on Blau syndrome/early-onset sarcoidosis]. 2013 Apr 1
26 23709157 NOD2 mutations affect muramyl dipeptide stimulation of human B lymphocytes and interact with other IBD-associated genes. 2013 Sep 1
27 23936340 Identification of benzimidazole diamides as selective inhibitors of the nucleotide-binding oligomerization domain 2 (NOD2) signaling pathway. 2013 1
28 22286692 MIP-3α expression in macrophages is NOD dependent. 2012 1
29 22447076 NOD2 triggers an interleukin-32-dependent human dendritic cell program in leprosy. 2012 Mar 25 2
30 22549783 Pathogen sensing by nucleotide-binding oligomerization domain-containing protein 2 (NOD2) is mediated by direct binding to muramyl dipeptide and ATP. 2012 Jun 29 4
31 22700971 The c-Jun N-terminal kinase (JNK)-binding protein (JNKBP1) acts as a negative regulator of NOD2 protein signaling by inhibiting its oligomerization process. 2012 Aug 24 1
32 23213202 RNAi screening identifies mediators of NOD2 signaling: implications for spatial specificity of MDP recognition. 2012 Dec 26 2
33 21040358 NOD2 controls the nature of the inflammatory response and subsequent fate of Mycobacterium tuberculosis and M. bovis BCG in human macrophages. 2011 Mar 1
34 21146253 The complex interplay of NOD-like receptors and the autophagy machinery in the pathophysiology of Crohn disease. 2011 Jun-Jul 1
35 21744420 Antimicrobial peptide response to blood translocation of bacterial DNA in Crohn's disease is affected by NOD2/CARD15 genotype. 2011 Aug 2
36 21886831 Down-regulated NOD2 by immunosuppressants in peripheral blood cells in patients with SLE reduces the muramyl dipeptide-induced IL-10 production. 2011 1
37 19856414 MDP-NOD2 stimulation induces HNP-1 secretion, which contributes to NOD2 antibacterial function. 2010 May 1
38 19948723 Direct and indirect induction by 1,25-dihydroxyvitamin D3 of the NOD2/CARD15-defensin beta2 innate immune pathway defective in Crohn disease. 2010 Jan 22 1
39 20052476 Altered cytokine profiles of mononuclear cells after stimulation in a patient with Blau syndrome. 2010 Jun 1
40 20524760 NOD2/CARD15: geographic differences in the Spanish population and clinical applications in Crohn's disease. 2010 May 1
41 20698950 NOD2-C2 - a novel NOD2 isoform activating NF-kappaB in a muramyl dipeptide-independent manner. 2010 Aug 10 2
42 20816488 Self and nonself recognition with bacterial and animal glycans, surveys by synthetic chemistry. 2010 1
43 21071776 Chronic yersiniosis due to defects in the TLR5 and NOD2 recognition pathways. 2010 Oct 1
44 17941075 Muramyl dipeptide-induced differential gene expression in NOD2 mutant and wild-type Crohn's disease patient-derived dendritic cells. 2008 Feb 1
45 18240302 Monocyte-derived dendritic cells from Crohn patients show differential NOD2/CARD15-dependent immune responses to bacteria. 2008 Jun 1
46 18507017 Gene polymorphisms of the NOD-2/CARD-15 gene and the risk of gastric cancer in Germany. 2008 Mar-Apr 1
47 19103524 NOD2 engagement induces proinflammatory cytokine production, but not apoptosis, in leukocytes isolated from patients with Crohn's disease. 2008 Dec 3
48 16964285 Mechanism of ASC-mediated apoptosis: bid-dependent apoptosis in type II cells. 2007 Mar 15 1
49 17621555 NOD2 and defensins: translating innate to adaptive immunity in Crohn's disease. 2007 1
50 17967410 Intracellular NOD-like receptors in host defense and disease. 2007 Oct 1