Indomethacin

cytochrome c oxidase I, mitochondrial ; Rattus norvegicus







47 Article(s)
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1 32097765 Peripheral-to-central immune communication at the area postrema glial-barrier following bleomycin-induced sterile lung injury in adult rats. 2020 Jul 2
2 30590313 Resveratrol enhances the protective effects of JBP485 against indomethacin-induced rat intestinal damage in vivo and vitro through up-regulating oligopeptide transporter 1 (Pept1). 2019 Mar 1
3 26439477 Protective activity of crocin against indomethacin-induced gastric lesions in rats. 2016 Jan 1
4 23117109 Signal transduction and modulating pathways in tryptamine-evoked vasopressor responses of the rat isolated perfused mesenteric bed. 2013 Jan 1
5 22328075 Design, synthesis and preliminary pharmacological evaluation of new non-steroidal anti-inflammatory agents having a 4-(methylsulfonyl) aniline pharmacophore. 2012 Feb 10 1
6 22948792 The cyclooxygenase and nitric oxide synthesis/pathways mediate the inhibitory serotonergic response to the pressor effect elicited by sympathetic stimulation in long-term diabetic pithed rats. 2012 1
7 23071636 Attenuation of renovascular damage in Zucker diabetic fatty rat by NWT-03, an egg protein hydrolysate with ACE- and DPP4-inhibitory Activity. 2012 1
8 23209788 Increased cyclooxygenase-2-derived prostanoids contributes to the hyperreactivity to noradrenaline in mesenteric resistance arteries from offspring of diabetic rats. 2012 2
9 21262224 Aldosterone alters the participation of endothelial factors in noradrenaline vasoconstriction differently in resistance arteries from normotensive and hypertensive rats. 2011 Mar 11 2
10 22001990 Effect of indometacin pretreatment on protamine sulfate-mediated relaxation of the isolated rat uterus: the role of the antioxidative defense system. 2011 1
11 19221012 Arachidonic acid metabolites follow the preferential course of cyclooxygenase pathway for the basal tone in the internal anal sphincter. 2009 Apr 1
12 19845835 Possible involvement of microglia containing cyclooxygenase-1 in the accumulation of gonadotrophin-releasing hormone in the preoptic area in female rats. 2009 Dec 1
13 17989504 Effect of cyclooxygenase and nitric oxide synthase inhibitors on streptozotocin-induced hyperalgesia in rats. 2008 1
14 18497304 Cyclooxygenases 1 and 2 contribute to peroxynitrite-mediated inflammatory pain hypersensitivity. 2008 Sep 1
15 18590745 Clozapine interacts with the glycine site of the NMDA receptor: electrophysiological studies of dopamine neurons in the rat ventral tegmental area. 2008 Aug 1 1
16 19066421 Effect of cyclooxygenase and nitric oxide synthase inhibitors on vincristine induced hyperalgesia in rats. 2008 Sep-Oct 2
17 20165558 Tumor Necrosis Factor-α Suppresses Activation of Sustained Potassium Currents in Rat Small Diameter Sensory Neurons. 2008 Jan 1 1
18 17245358 Endothelium-dependent metabolism by endocannabinoid hydrolases and cyclooxygenases limits vasorelaxation to anandamide and 2-arachidonoylglycerol. 2007 Mar 1
19 17704356 Cyclooxygenase inhibition limits blood-brain barrier disruption following intracerebral injection of tumor necrosis factor-alpha in the rat. 2007 Nov 1
20 16371234 Involvement of COX-1 and up-regulated prostaglandin E synthases in phosphatidylserine liposome-induced prostaglandin E2 production by microglia. 2006 Mar 1
21 16416446 Effects of COX-1 and COX-2 inhibitors on the firing of rat midbrain dopaminergic neurons--possible involvement of endogenous kynurenic acid. 2006 Apr 1
22 16473424 Zaltoprofen, a non-steroidal anti-inflammatory drug, inhibits bradykinin-induced pain responses without blocking bradykinin receptors. 2006 Apr 1
23 16868036 Prostaglandin/cyclooxygenase pathway in ghrelin-induced gastroprotection against ischemia-reperfusion injury. 2006 Oct 1
24 17008468 Effects of selective inhibition of cyclooxygenase and lipooxygenase pathways in follicle rupture and ovulation in the rat. 2006 Oct 1
25 15564788 Are prostanoids related to positive inotropism by UTP and ATP? 2005 Mar 1
26 16172547 Biphasic effect of prostaglandin E2 in a rat model of esophagitis mediated by EP1 receptors: relation to pepsin secretion. 2005 1
27 16343605 Worsening effect of partial sleep deprivation on indomethacin-induced gastric mucosal damage. 2005 Nov 1
28 15104355 Functional mechanism underlying COX-2 expression following administration of indomethacin in rat stomachs: importance of gastric hypermotility. 2004 Feb 1
29 15293235 Lesional RhoA+ cell numbers are suppressed by anti-inflammatory, cyclooxygenase-inhibiting treatment following subacute spinal cord injury. 2004 Sep 1
30 12581882 A Galphas protein-coupled membrane receptor, distinct from the classical oestrogen receptor, transduces rapid effects of oestradiol on [Ca2+]i in female rat distal colon. 2003 Jan 31 1
31 12711837 Anti-inflammatory effect and low ulcerogenic activity of etodolac, a cyclooxygenase-2 selective non-steroidal anti-inflammatory drug, on adjuvant-induced arthritis in rats. 2003 Jun 1
32 12832840 On the mechanisms underlying histamine induction of gastric mucosal lesions in rats with partial gastric vascular occlusion. 2003 Jun 1
33 14581763 Both selective COX-1 and COX-2 inhibitors aggravate gastric damage induced in rats by 2-deoxy-D-glucose. relation to gastric hypermotility and COX-2 expression. 2003 1
34 12136686 [Dexketoprofene, selective cox-1 inhibitor nsaids, without gastrointestinal injury in rats]. 2002 May 2
35 11487305 Stimulated release of arachidonic acid from rat liver cells by celecoxib and indomethacin. 2001 Jul 1
36 11516414 A stable prostacyclin analog enhances ectopic activity in rat sensory neurons following neuropathic injury. 2001 Jun 15 1
37 11519792 Changes in prostaglandin E2 (PGE2) levels in paw exudate, stomach and kidney of arthritic rats: effects of flosulide. 2001 Aug 1
38 9882752 Regulation of anion secretion by cyclo-oxygenase and prostanoids in cultured epididymal epithelia from the rat. 1999 Feb 1 1
39 10205009 Limited anti-inflammatory efficacy of cyclo-oxygenase-2 inhibition in carrageenan-airpouch inflammation. 1999 Mar 2
40 9700141 Impaired hypoxic vasoconstriction in intraacinar microvasculature in hyperoxia-exposed rat lungs. 1998 Aug 1
41 9152412 Prostaglandin E2 production dependent upon cyclooxygenase-1 and cyclooxygenase-2 and its contradictory modulation by auranofin in rat peritoneal macrophages. 1997 May 1
42 9309800 Evaluation of pharmacological profile of meloxicam as an anti-inflammatory agent, with particular reference to its relative selectivity for cyclooxygenase-2 over cyclooxygenase-1. 1997 Jul 1
43 9351500 Cyclo-oxygenase isozymes in mucosal ulcergenic and functional responses following barrier disruption in rat stomachs. 1997 Oct 1
44 9414035 Comparative study of the effects of indomethacin and NS-398, a selective cyclooxygenase 2 inhibitor, on duodenal bicarbonate secretion induced by luminal acidification in rats. 1997 Oct 1
45 8915776 Inducible cyclo-oxygenase (COX-2) mediates the induction of bone formation by mechanical loading in vivo. 1996 Nov 1
46 8140262 NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro. 1994 Jan 1
47 8159730 Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic. 1994 Apr 12 1