Glycine

peptidylglycine alpha-amidating monooxygenase ; Homo sapiens







27 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 30271955 Effects of copper occupancy on the conformational landscape of peptidylglycine α-hydroxylating monooxygenase. 2018 1
2 26024288 Inactivation of peptidylglycine α-hydroxylating monooxygenase by cinnamic acid analogs. 2016 Aug 2
3 26982589 Stopped-Flow Studies of the Reduction of the Copper Centers Suggest a Bifurcated Electron Transfer Pathway in Peptidylglycine Monooxygenase. 2016 Apr 5 1
4 23247335 Coordination of peroxide to the Cu(M) center of peptidylglycine α-hydroxylating monooxygenase (PHM): structural and computational study. 2013 Feb 1
5 20958070 Differential reactivity between two copper sites in peptidylglycine α-hydroxylating monooxygenase. 2010 Nov 10 1
6 21043511 Evidence for substrate preorganization in the peptidylglycine α-amidating monooxygenase reaction describing the contribution of ground state structure to hydrogen tunneling. 2010 Nov 24 3
7 19170548 Involvement of metals in enzymatic and nonenzymatic decomposition of C-terminal alpha-hydroxyglycine to amide: an implication for the catalytic role of enzyme-bound zinc in the peptidylamidoglycolate lyase reaction. 2009 Feb 24 2
8 17002377 The catalytic mechanism of peptidylglycine alpha-hydroxylating monooxygenase investigated by computer simulation. 2006 Oct 4 2
9 14975510 A new proposal for the mechanism of glycine hydroxylation as catalyzed by peptidylglycine alpha-hydroxylating monooxygenase (PHM). 2004 3
10 12590568 Oxygen and hydrogen isotope effects in an active site tyrosine to phenylalanine mutant of peptidylglycine alpha-hydroxylating monooxygenase: mechanistic implications. 2003 Feb 25 1
11 12646261 Glutathione, S-substituted glutathiones, and leukotriene C4 as substrates for peptidylglycine alpha-amidating monooxygenase. 2003 Apr 1 3
12 12667480 Mechanisms of inhibition of phenylalanine ammonia-lyase by phenol inhibitors and phenol/glycine synergistic inhibitors. 2003 Apr 15 1
13 11221851 Expression of adrenomedullin and peptide amidation activity in human prostate cancer and in human prostate cancer cell lines. 2001 Feb 1 1
14 10666288 The enzymatic formation of novel bile acid primary amides. 2000 Feb 15 3
15 10891082 Peptidylglycine-alpha-hydroxylating monooxygenase generates two hydroxylated products from its mechanism-based suicide substrate, 4-phenyl-3-butenoic acid. 2000 Jul 11 1
16 11097175 Amidation of salicyluric acid and gentisuric acid: a possible role for peptidylglycine alpha-amidating monooxygenase in the metabolism of aspirin. 2000 Nov 1 3
17 10563791 Does superoxide channel between the copper centers in peptidylglycine monooxygenase? A new mechanism based on carbon monoxide reactivity. 1999 Nov 16 3
18 9624125 Mutations causing neurodegeneration in Caenorhabditis elegans drastically alter the pH sensitivity and inactivation of the mammalian H+-gated Na+ channel MDEG1. 1998 Jun 19 2
19 9799553 The behavior of substrate analogues and secondary deuterium isotope effects in the phenylalanine ammonia-lyase reaction. 1998 Nov 1 2
20 9806894 Kinetic isotope effects of peptidylglycine alpha-hydroxylating mono-oxygenase reaction. 1998 Nov 15 3
21 7493955 Reaction versus subsite stereospecificity of peptidylglycine alpha-monooxygenase and peptidylamidoglycolate lyase, the two enzymes involved in peptide amidation. 1995 Dec 8 2
22 8198547 NN-dimethyl-1,4-phenylenediamine as an alternative reductant for peptidylglycine alpha-amidating mono-oxygenase catalysis. 1994 May 15 1
23 8102327 Peptide alpha-amidation activity in human plasma: relationship to gastrin processing. 1993 Jul 1
24 1839957 Modulatory effects of interferon-gamma on the fibronectin receptor function of squamous cell carcinoma cells in vitro. 1991 Dec 2
25 1985904 Gastrin-amidating enzyme in the porcine pituitary and antrum. Characterization of molecular forms and substrate specificity. 1991 Jan 5 2
26 2059626 Functional and structural characterization of peptidylamidoglycolate lyase, the enzyme catalyzing the second step in peptide amidation. 1991 Jun 25 1
27 2372538 Novel substrates and inhibitors of peptidylglycine alpha-amidating monooxygenase. 1990 May 15 1