Acetylcysteine

BCL2 associated X, apoptosis regulator ; Homo sapiens







49 Article(s)
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1 34861471 Arsenite-induced cytotoxicity is regulated by p38-SQSTM1/p62 and JNK-BNIP3L/Nix signaling in lung cancer cells. 2022 Jan 8 1
2 33880372 ROS-Triggered Autophagy Is Involved in PFOS-Induced Apoptosis of Human Embryo Liver L-02 Cells. 2021 2
3 34156614 N-acetylcysteine ameliorate cytotoxic injury in piglets sertoli cells induced by zearalenone and deoxynivalenol. 2021 Nov 1
4 31995555 Application of non-invasive low-intensity pulsed electric field with thermal cycling-hyperthermia for synergistically enhanced anticancer effect of chlorogenic acid on PANC-1 cells. 2020 2
5 32536618 Synergistic Induction of Apoptosis by the Combination of an Axl Inhibitor and Auranofin in Human Breast Cancer Cells. 2020 Sep 1 1
6 31524245 N‑acetyl cysteine inhibits lipopolysaccharide‑induced apoptosis of human umbilical vein endothelial cells via the p38MAPK signaling pathway. 2019 Sep 1
7 30603674 N-acetylcysteine protects hepatocytes from hypoxia-related cell injury. 2018 Dec 2
8 28178219 Altholactone Inhibits NF-κB and STAT3 Activation and Induces Reactive Oxygen Species-Mediated Apoptosis in Prostate Cancer DU145 Cells. 2017 Feb 7 2
9 28380464 Heat stress induces intestinal injury through lysosome- and mitochondria-dependent pathway in vivo and in vitro. 2017 Jun 20 1
10 28399781 PCB 118-induced endothelial cell apoptosis is partially mediated by excessive ROS production. 2017 Jun 1
11 28804952 Evaluation of cytotoxicity of propofol and its related mechanism in glioblastoma cells and astrocytes. 2017 Dec 1
12 26809061 Nickel(II)-induced nasal epithelial toxicity and oxidative mitochondrial damage. 2016 Mar 1
13 26828938 Apoptosis of THP-1 Macrophages Induced by Pseudohypericin-Mediated Sonodynamic Therapy Through the Mitochondria-Caspase Pathway. 2016 1
14 27028622 Nicotine-Induced Apoptosis in Human Renal Proximal Tubular Epithelial Cells. 2016 1
15 27669171 Reactive oxygen species contribute toward Smac mimetic/temozolomide-induced cell death in glioblastoma cells. 2016 Nov 1
16 25653524 The efficacy and mechanism of apoptosis induction by hypericin-mediated sonodynamic therapy in THP-1 macrophages. 2015 1
17 25909282 Synergistic protection of N-acetylcysteine and ascorbic acid 2-phosphate on human mesenchymal stem cells against mitoptosis, necroptosis and apoptosis. 2015 Apr 24 1
18 26296767 HCV upregulates Bim through the ROS/JNK signalling pathway, leading to Bax-mediated apoptosis. 2015 Sep 3
19 26305534 The Antioxidant N-Acetylcysteine Inhibits Inflammatory and Apoptotic Processes in Human Conjunctival Epithelial Cells in a High-Glucose Environment. 2015 Aug 1
20 26394653 Total Tanshinones-Induced Apoptosis and Autophagy Via Reactive Oxygen Species in Lung Cancer 95D Cells. 2015 1
21 25202081 Equol induces mitochondria-mediated apoptosis of human cervical cancer cells. 2014 Sep 2
22 23386420 N-acetyl-L-cysteine inhibits bleomycin induced apoptosis in malignant testicular germ cell tumors. 2013 Jul 1
23 23782641 Phaseoloideside E, a novel natural triterpenoid saponin identified from Entada phaseoloides, induces apoptosis in Ec-109 esophageal cancer cells through reactive oxygen species generation. 2013 1
24 22419868 Titanium dioxide induces apoptotic cell death through reactive oxygen species-mediated Fas upregulation and Bax activation. 2012 1
25 22562160 Effects of N-acetylcystein on bleomycin-induced apoptosis in malignant testicular germ cell tumors. 2012 Dec 1
26 22824464 NG, a novel PABA/NO-based oleanolic acid derivative, induces human hepatoma cell apoptosis via a ROS/MAPK-dependent mitochondrial pathway. 2012 Sep 15 2
27 23251571 ROS production is essential for the apoptotic function of E2F1 in pheochromocytoma and neuroblastoma cell lines. 2012 1
28 19592481 Bufalin Induces Reactive Oxygen Species Dependent Bax Translocation and Apoptosis in ASTC-a-1 Cells. 2011 2
29 21777666 Barakol-induced apoptosis in P19 cells through generation of reactive oxygen species and activation of caspase-9. 2011 Sep 2 1
30 20358478 Mulberry fruit (Moris fructus) extracts induce human glioma cell death in vitro through ROS-dependent mitochondrial pathway and inhibits glioma tumor growth in vivo. 2010 2
31 20557081 Methyl antcinate A from Antrodia camphorata induces apoptosis in human liver cancer cells through oxidant-mediated cofilin- and Bax-triggered mitochondrial pathway. 2010 Jul 19 1
32 20674558 1-(3',4',5'-Trimethoxyphenyl)-3-(3'',4''-dimethoxy-2''-hydroxyphenyl)-propane with microtubule-depolymerizing ability induces G2/M phase arrest and apoptosis in HepG2 cells. 2010 Oct 6 2
33 20981856 Acrylonitrile induced apoptosis via oxidative stress in neuroblastoma SH-SY5Y cell. 2010 Oct 1
34 18323457 MSFTZ, a flavanone derivative, induces human hepatoma cell apoptosis via a reactive oxygen species- and caspase-dependent mitochondrial pathway. 2008 Jun 1
35 18547707 Mechanisms of chromium (VI)-induced apoptosis in anterior pituitary cells. 2008 Jul 30 2
36 18628592 Mitochondrial transmembrane potential and reactive oxygen species generation regulate the enhanced effect of CCCP on TRAIL-induced SNU-638 cell apoptosis. 2008 Jun 1
37 17237268 Combination treatment with arsenic trioxide and phytosphingosine enhances apoptotic cell death in arsenic trioxide-resistant cancer cells. 2007 Jan 1
38 17289842 Oxidized low-density lipoprotein stimulates p53-dependent activation of proapoptotic Bax leading to apoptosis of differentiated endothelial progenitor cells. 2007 May 1
39 17440103 Sanguinarine-dependent induction of apoptosis in primary effusion lymphoma cells. 2007 Apr 15 1
40 17542780 Morphine inhibits doxorubicin-induced reactive oxygen species generation and nuclear factor kappaB transcriptional activation in neuroblastoma SH-SY5Y cells. 2007 Sep 1 4
41 17549348 Reactive oxygen species regulate Bax translocation and mitochondrial transmembrane potential, a possible mechanism for enhanced TRAIL-induced apoptosis by CCCP. 2007 Jul 1
42 17917164 Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts. 2007 Sep 1
43 16616945 Activation of peroxisome proliferator-activated receptor-gamma (PPARgamma) induces cell death through MAPK-dependent mechanism in osteoblastic cells. 2006 Sep 1 1
44 15735709 Arsenic trioxide (As(2)O(3)) induces apoptosis through activation of Bax in hematopoietic cells. 2005 May 5 2
45 15941563 Emodin induces apoptosis in human lung adenocarcinoma cells through a reactive oxygen species-dependent mitochondrial signaling pathway. 2005 Jul 15 1
46 11841797 Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca(2+)-dependent endonuclease. 2002 Jan 15 1
47 10777712 The differential expression of apoptosis factors in the alveolar epithelium is redox sensitive and requires NF-kappaB (RelA)-selective targeting. 2000 Apr 29 1
48 11042671 Ordering of ceramide formation, caspase activation, and Bax/Bcl-2 expression during etoposide-induced apoptosis in C6 glioma cells. 2000 Sep 1
49 9210957 Suppression of nitric oxide-induced apoptosis by N-acetyl-L-cysteine through modulation of glutathione, bcl-2, and bax protein levels. 1997 Jun 1