gemcitabine

KRAS proto-oncogene, GTPase ; Homo sapiens







34 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35088684 Moving towards dawn: KRas signaling and treatment in pancreatic ductal adenocarcinoma. 2022 Jan 28 1
2 35158819 Kras Gene Analysis Using Liquid-Based Cytology Specimens Predicts Therapeutic Responses and Prognosis in Patients with Pancreatic Cancer. 2022 Jan 22 1
3 35615894 Acute generalized exanthematous pustulosis caused by gemcitabine after nivolumab in metastatic lung adenocarcinoma followed by a dramatic tumor response: A case report. 2022 May 26 1
4 32515291 Synergistic effects of piperlongumine and gemcitabine against KRAS mutant lung cancer. 2021 Apr 3
5 33662667 Suppression of Wnt/β-catenin and RAS/ERK pathways provides a therapeutic strategy for gemcitabine-resistant pancreatic cancer. 2021 Apr 16 1
6 33744388 Intracellular KRAS-specific antibody enhances the anti-tumor efficacy of gemcitabine in pancreatic cancer by inducing endosomal escape. 2021 Jun 1 3
7 34660806 Development of a KRAS-Associated Metabolic Risk Model for Prognostic Prediction in Pancreatic Cancer. 2021 1
8 34781244 One-shot dual gene editing for drug-resistant pancreatic cancer therapy. 2021 Dec 3
9 31838939 Phase II study of gemcitabine, oxaliplatin and capecitabine in patients with KRAS exon 2 mutated biliary tract cancers. 2020 Mar 1
10 32655498 A Novel E2F1-EP300-VMP1 Pathway Mediates Gemcitabine-Induced Autophagy in Pancreatic Cancer Cells Carrying Oncogenic KRAS. 2020 2
11 32828430 Induction of potent cell growth inhibition by schizophyllan/K-ras antisense complex in combination with gemcitabine. 2020 Sep 15 1
12 33216236 Nanoformulation of Apolipoprotein E3-Tagged Liposomal Nanoparticles for the co-Delivery of KRAS-siRNA and Gemcitabine for Pancreatic Cancer Treatment. 2020 Nov 20 1
13 31508487 ROS/KRAS/AMPK Signaling Contributes to Gemcitabine-Induced Stem-like Cell Properties in Pancreatic Cancer. 2019 Sep 27 1
14 29564165 A KRAS wild type mutational status confers a survival advantage in pancreatic ductal adenocarcinoma. 2018 Feb 1
15 29596326 Differentiation Therapy Targeting the β-Catenin/CBP Interaction in Pancreatic Cancer. 2018 Mar 29 1
16 30083262 Targeting S1PR1/STAT3 loop abrogates desmoplasia and chemosensitizes pancreatic cancer to gemcitabine. 2018 1
17 30217561 KRAS targeting antibody synergizes anti-cancer activity of gemcitabine against pancreatic cancer. 2018 Dec 1 3
18 28060183 Gemcitabine Enhances Kras-MEK-Induced Matrix Metalloproteinase-10 Expression Via Histone Acetylation in Gemcitabine-Resistant Pancreatic Tumor-initiating Cells. 2017 Feb 2
19 28407465 KRAS G12C mutation as a poor prognostic marker of pemetrexed treatment in non-small cell lung cancer. 2017 May 1
20 28961832 Gemcitabine combined with the monoclonal antibody nimotuzumab is an active first-line regimen in KRAS wildtype patients with locally advanced or metastatic pancreatic cancer: a multicenter, randomized phase IIb study. 2017 Oct 1 1
21 27101576 miR-216b Targets FGFR1 and Confers Sensitivity to Radiotherapy in Pancreatic Ductal Adenocarcinoma Patients Without EGFR or KRAS Mutation. 2016 Oct 1
22 27335026 TACTIC: a multicentre, open-label, single-arm phase II trial of panitumumab, cisplatin, and gemcitabine in biliary tract cancer. 2016 Aug 1
23 25946136 Let-7 Sensitizes KRAS Mutant Tumor Cells to Chemotherapy. 2015 2
24 26156229 The combination of intravenous Reolysin and gemcitabine induces reovirus replication and endoplasmic reticular stress in a patient with KRAS-activated pancreatic cancer. 2015 Jul 10 2
25 24960403 Phase II study of gemcitabine, oxaliplatin in combination with panitumumab in KRAS wild-type unresectable or metastatic biliary tract and gallbladder cancer. 2014 Jul 29 4
26 25216706 Recombinant expression of different mutant K-ras gene in pancreatic cancer Bxpc-3 cells and its effects on chemotherapy sensitivity. 2014 Oct 1
27 23724098 Prognostic and predictive value of KRAS mutations in advanced non-small cell lung cancer. 2013 1
28 21289082 Context dependence of checkpoint kinase 1 as a therapeutic target for pancreatic cancers deficient in the BRCA2 tumor suppressor. 2011 Apr 1
29 21738581 Tissue and serum microRNAs in the Kras(G12D) transgenic animal model and in patients with pancreatic cancer. 2011 1
30 21862683 Impact of KRAS mutations on clinical outcomes in pancreatic cancer patients treated with first-line gemcitabine-based chemotherapy. 2011 Oct 2
31 21894049 KRAS mutation in metastatic pancreatic ductal adenocarcinoma: results of a multicenter phase II study evaluating efficacy of cetuximab plus gemcitabine/oxaliplatin (GEMOXCET) in first-line therapy. 2011 1
32 22966286 Antitumor activity of erlotinib in combination with gemcitabine in in vitro and in vivo models of KRAS-mutated pancreatic cancers. 2010 Mar 1
33 18430374 Synergy of gemcitabine and lidamycin associated with NF-kappaB downregulation in pancreatic carcinoma cells. 2008 May 1
34 17489984 K-ras oncogene silencing strategy reduces tumor growth and enhances gemcitabine chemotherapy efficacy for pancreatic cancer treatment. 2007 Jul 1