| 1 |
34983833 | Vitamin C Deficiency Causes Cell Type-Specific Epigenetic Reprogramming and Acute Tubular Necrosis in a Mouse Model. | 2022 Mar |
1 |
| 2 |
32797675 | Ascorbate deficiency decreases dopamine release in gulo-/- and APP/PSEN1 mice. | 2021 May |
1 |
| 3 |
34229598 | Age and Dietary Vitamin C Intake Affect Brain Physiology in Genetically Modified Mice Expressing Human Lipoprotein(A) and Unable to Synthesize Vitamin C. | 2021 |
1 |
| 4 |
34643398 | Vitamin C Differentially Impacts the Serum Proteome Profile in Female and Male Mice. | 2021 Nov 5 |
2 |
| 5 |
32913121 | Ascorbic acid enhances low-density lipoprotein receptor expression by suppressing proprotein convertase subtilisin/kexin 9 expression. | 2020 Nov 20 |
3 |
| 6 |
29180474 | Vitamin C Sensitizes Melanoma to BET Inhibitors. | 2018 Jan 15 |
1 |
| 7 |
30025088 | Ascorbate Suppresses VEGF Expression in Retinal Pigment Epithelial Cells. | 2018 Jul 2 |
1 |
| 8 |
30172223 | Altered glutamate clearance in ascorbate deficient mice increases seizure susceptibility and contributes to cognitive impairment in APP/PSEN1 mice. | 2018 Nov |
1 |
| 9 |
30219227 | Gulo regulates the proliferation, apoptosis and mesenchymal-to-epithelial transformation of metanephric mesenchyme cells via inhibiting Six2. | 2018 Oct 12 |
2 |
| 10 |
28115164 | Inhibition of glutathione production by L-S,R-buthionine sulfoximine activates hepatic ascorbate synthesis - A unique anti-oxidative stress mechanism in mice. | 2017 Feb 26 |
1 |
| 11 |
28210072 | The Parenteral Vitamin C Improves Sepsis and Sepsis-Induced Multiple Organ Dysfunction Syndrome via Preventing Cellular Immunosuppression. | 2017 |
1 |
| 12 |
26898166 | Red ginseng and vitamin C increase immune cell activity and decrease lung inflammation induced by influenza A virus/H1N1 infection. | 2016 Mar |
4 |
| 13 |
26922388 | Vitamin C modulates the metabolic and cytokine profiles, alleviates hepatic endoplasmic reticulum stress, and increases the life span of Gulo-/- mice. | 2016 Mar |
8 |
| 14 |
27573077 | Lipoprotein(a) and vitamin C impair development of breast cancer tumors in Lp(a)+; Gulo-/- mice. | 2016 Sep |
3 |
| 15 |
27800507 | Ascorbate availability affects tumor implantation-take rate and increases tumor rejection in Gulo-/- mice. | 2016 |
1 |
| 16 |
25354695 | Restoring physiological levels of ascorbate slows tumor growth and moderates HIF-1 pathway activity in Gulo(-/-) mice. | 2015 Feb |
1 |
| 17 |
25977985 | Vitamin C Deficiency Causes Severe Defects in the Development of the Neonatal Cerebellum and in the Motor Behaviors of Gulo(-/-) Mice. | 2015 Dec 1 |
2 |
| 18 |
26057690 | Hepatoprotective effect of vitamin C on lithocholic acid-induced cholestatic liver injury in Gulo(-/-) mice. | 2015 Sep 5 |
2 |
| 19 |
23917525 | Attenuation of sepsis-induced organ injury in mice by vitamin C. | 2014 Sep |
1 |
| 20 |
25133246 | Genome wide analysis of sex difference in gene expression profiles of bone formations using sfx mice and BXD RI strains. | 2014 |
2 |
| 21 |
28548062 | Gulonolactone Addition to Human Hepatocellular Carcinoma Cells with Gene Transfer of Gulonolactone Oxidase Restores Ascorbate Biosynthesis and Reduces Hypoxia Inducible Factor 1. | 2014 Mar 5 |
4 |
| 22 |
23106783 | Behavioral and monoamine changes following severe vitamin C deficiency. | 2013 Feb |
1 |
| 23 |
23321552 | Combined vitamin C and E deficiency induces motor defects in gulo(-/-)/SVCT2(+/-) mice. | 2013 Jul |
1 |
| 24 |
23472641 | In vivo consequence of vitamin C insufficiency in liver injury: vitamin C ameliorates T-cell-mediated acute liver injury in gulo(-/-) mice. | 2013 Dec 10 |
5 |
| 25 |
23700397 | Vitamin C Is an Essential Factor on the Anti-viral Immune Responses through the Production of Interferon-α/β at the Initial Stage of Influenza A Virus (H3N2) Infection. | 2013 Apr |
1 |
| 26 |
23886864 | Vitamin C prevents stress-induced damage on the heart caused by the death of cardiomyocytes, through down-regulation of the excessive production of catecholamine, TNF-α, and ROS production in Gulo(-/-)Vit C-Insufficient mice. | 2013 Dec |
6 |
| 27 |
24035909 | Helicobacter pylori infection combined with DENA revealed altered expression of p53 and 14-3-3 isoforms in Gulo-/- mice. | 2013 Nov 25 |
1 |
| 28 |
24386598 | Ascorbic acid insufficiency induces the severe defect on bone formation via the down-regulation of osteocalcin production. | 2013 Dec |
7 |
| 29 |
22296218 | Effect of vitamin C deficiency during postnatal development on adult behavior: functional phenotype of Gulo-/- knockout mice. | 2012 Apr |
3 |
| 30 |
22306178 | Depletion of ascorbic acid impairs NK cell activity against ovarian cancer in a mouse model. | 2012 Sep |
5 |
| 31 |
22536166 | The analysis of vitamin C concentration in organs of gulo(-/-) mice upon vitamin C withdrawal. | 2012 Feb |
6 |
| 32 |
21346252 | Vitamin C is dispensable for oxygen sensing in vivo. | 2011 May 19 |
1 |
| 33 |
21878346 | Effects of ascorbic acid on carcinogenicity and acute toxicity of nickel subsulfide, and on tumor transplants growth in gulonolactone oxidase knock-out mice and wild-type C57BL mice. | 2011 Nov 15 |
4 |
| 34 |
21931508 | Differential gene expression between wild-type and Gulo-deficient mice supplied with vitamin C. | 2011 Jul |
1 |
| 35 |
22217712 | Ascorbate depletion increases growth and metastasis of melanoma cells in vitamin C deficient mice. | 2011 Dec |
3 |
| 36 |
20484858 | Vitamin C deficiency fails to protect mice from malaria. | 2010 |
1 |
| 37 |
19690176 | Beta-catenin regulates vitamin C biosynthesis and cell survival in murine liver. | 2009 Oct 9 |
4 |
| 38 |
18466336 | Elevated oxidative stress and sensorimotor deficits but normal cognition in mice that cannot synthesize ascorbic acid. | 2008 Aug |
3 |
| 39 |
18764764 | Restoration of vitamin C synthesis in transgenic Gulo-/- mice by helper-dependent adenovirus-based expression of gulonolactone oxidase. | 2008 Dec |
10 |
| 40 |
17264304 | Ascorbate deficiency results in impaired neutrophil apoptosis and clearance and is associated with up-regulation of hypoxia-inducible factor 1alpha. | 2007 May |
3 |
| 41 |
17325743 | Depletion of ascorbic acid restricts angiogenesis and retards tumor growth in a mouse model. | 2007 Jan |
1 |
| 42 |
29350811 | Ascorbate deficiency results in impaired neutrophil apoptosis and clearance and is associated with up-regulation of hypoxia-inducible factor 1α. | 2007 May |
3 |
| 43 |
16352673 | Ascorbic acid-independent synthesis of collagen in mice. | 2006 Jun |
2 |
| 44 |
16632110 | Vitamin C fails to protect amino acids and lipids from oxidation during acute inflammation. | 2006 May 1 |
4 |
| 45 |
16737683 | Ascorbic acid synthesis due to L-gulono-1,4-lactone oxidase expression enhances NO production in endothelial cells. | 2006 Jul 14 |
1 |
| 46 |
16988135 | Vitamin C deficiency increases the lung pathology of influenza virus-infected gulo-/- mice. | 2006 Oct |
1 |
| 47 |
15674730 | A deletion causing spontaneous fracture identified from a candidate region of mouse Chromosome 14. | 2005 Jan |
2 |
| 48 |
16059632 | Spontaneous fractures in the mouse mutant sfx are caused by deletion of the gulonolactone oxidase gene, causing vitamin C deficiency. | 2005 Sep |
5 |
| 49 |
14962674 | Functional rescue of vitamin C synthesis deficiency in human cells using adenoviral-based expression of murine l-gulono-gamma-lactone oxidase. | 2004 Mar |
6 |
| 50 |
10639167 | Aortic wall damage in mice unable to synthesize ascorbic acid. | 2000 Jan 18 |
2 |