Uric Acid

caspase 1 ; Homo sapiens







25 Article(s)
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Pub. Year
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1 33389490 The roles of NLRP3 inflammasome-mediated signaling pathways in hyperuricemic nephropathy. 2021 Mar 1
2 33830232 1'-Acetoxychavicol acetate inhibits NLRP3-dependent inflammasome activation via mitochondrial ROS suppression. 2021 Jun 18 2
3 33902703 Cold-inducible RNA-binding protein (CIRP) potentiates uric acid-induced IL-1β production. 2021 Apr 26 1
4 31927504 Uric acid increases IL-1β secretion and Caspase-1 activation in PBMCs of Behçet's disease patients: The in vitro immunomodulatory effect of xanthine oxidase inhibitor Allopurinol. 2020 Mar 2
5 30612459 Rhein, An Anthraquinone Drug, Suppresses the NLRP3 Inflammasome and Macrophage Activation in Urate Crystal-Induced Gouty Inflammation. 2019 1
6 30833078 TXNIP-mediated nuclear factor-κB signaling pathway and intracellular shifting of TXNIP in uric acid-induced NLRP3 inflammasome. 2019 Apr 16 1
7 31358323 Anti-inflammatory effect of artemisinin on uric acid-induced NLRP3 inflammasome activation through blocking interaction between NLRP3 and NEK7. 2019 Sep 17 1
8 31412804 Uric acid regulates NLRP3/IL-1β signaling pathway and further induces vascular endothelial cells injury in early CKD through ROS activation and K+ efflux. 2019 Aug 14 1
9 31819864 Calcium Pyrophosphate And Monosodium Urate Activate The NLRP3 Inflammasome Within Bladder Urothelium Via Reactive Oxygen Species And TXNIP. 2019 1
10 32082152 Exploring the Therapeutic Composition and Mechanism of Jiang-Suan-Chu-Bi Recipe on Gouty Arthritis Using an Integrated Approach Based on Chemical Profile, Network Pharmacology and Experimental Support Using Molecular Cell Biology. 2019 1
11 33693087 Hyperuricemia as a Risk Factor for Atrial Fibrillation Due to Soluble and Crystalized Uric Acid. 2019 Nov 1 1
12 30166062 High-mobility group box 1 is responsible for monosodium urate crystal-induced inflammation in human U937 macrophages. 2018 Sep 18 1
13 28569730 Inflammasomes and IL-1 biology in the pathogenesis of allograft dysfunction. 2017 Jun 1 1
14 26454448 Rebamipide Suppresses Monosodium Urate Crystal-Induced Interleukin-1β Production Through Regulation of Oxidative Stress and Caspase-1 in THP-1 Cells. 2016 Feb 1
15 27219123 Cytokine Profile in Gout: Inflammation Driven by IL-6 and IL-18? 2016 Jul 2
16 25813103 Soluble uric acid increases NALP3 inflammasome and interleukin-1β expression in human primary renal proximal tubule epithelial cells through the Toll-like receptor 4-mediated pathway. 2015 May 4
17 26435646 Urate crystals induce NLRP3 inflammasome-dependent IL-1β secretion and proliferation in isolated primary human T-cells. 2015 Jan-Mar 2
18 25261974 Monosodium urate crystal induced macrophage inflammation is attenuated by chondroitin sulphate: pre-clinical model for gout prophylaxis? 2014 Sep 27 1
19 25445147 Activation of NLRP3 inflammasome by crystalline structures via cell surface contact. 2014 Dec 2 1
20 23852607 In vivo evaluation of neutrophil recruitment in response to sterile particulates. 2013 1
21 24376319 Uric acid induces caspase-1 activation, IL-1β secretion and P2X7 receptor dependent proliferation in primary human lymphocytes. 2013 Apr 3
22 20632067 Involvement of xanthine oxidase and hypoxia-inducible factor 1 in Toll-like receptor 7/8-mediated activation of caspase 1 and interleukin-1β. 2011 Jan 1
23 18390571 Crystals of monosodium urate monohydrate enhance lipopolysaccharide-induced release of interleukin 1 beta by mononuclear cells through a caspase 1-mediated process. 2009 Feb 2
24 18638431 Colchicine: its mechanism of action and efficacy in crystal-induced inflammation. 2008 Jul 1
25 17442855 Caspase-1 inflammasomes in infection and inflammation. 2007 Aug 1