pyrazole

mitochondrially encoded cytochrome c oxidase II ; Homo sapiens







17 Article(s)
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1 35597858 Co(II), Ni(II), and Zn(II) complexes based on new hybrid imine-pyrazole ligands: structural, spectroscopic, and electronic properties. 2022 May 21 1
2 33015829 Design and synthesis of pyrazole-pyrazoline hybrids as cancer-associated selective COX-2 inhibitors. 2021 Jan 1
3 34243075 Optimization of pyrazole-based compounds with 1,2,4-triazole-3-thiol moiety as selective COX-2 inhibitors cardioprotective drug candidates: Design, synthesis, cyclooxygenase inhibition, anti-inflammatory, ulcerogenicity, cardiovascular evaluation, and molecular modeling studies. 2021 Sep 2
4 32707279 Discovery of novel aminophosphonate derivatives containing pyrazole moiety as potential selective COX-2 inhibitors. 2020 Sep 1
5 30769266 Discovery, synthesis and molecular corroborations of medicinally important novel pyrazoles; drug efficacy determinations through in silico, in vitro and cytotoxicity validations. 2019 May 1
6 31374529 Thiohydantoin derivatives incorporating a pyrazole core: Design, synthesis and biological evaluation as dual inhibitors of topoisomerase-I and cycloxygenase-2 with anti-cancer and anti-inflammatory activities. 2019 Oct 1
7 28720504 Synthesis of novel hybrids of pyrazole and coumarin as dual inhibitors of COX-2 and 5-LOX. 2017 Aug 15 2
8 27882369 Regio- and stereo-selective polymerization of 1,3-butadiene catalyzed by phosphorus-nitrogen PN3-pincer cobalt(ii) complexes. 2016 Dec 6 3
9 23565678 Developments in synthesis of the anti-inflammatory drug, celecoxib: a review. 2013 May 1
10 20692174 Synthesis, biological evaluation, and docking studies of novel heterocyclic diaryl compounds as selective COX-2 inhibitors. 2010 Sep 1 1
11 16297351 Evaluation of 2 celecoxib derivatives: analgesic effect and selectivity to cyclooxygenase-2/1. 2005 Dec 1
12 14751313 Synthesis and COX-2 inhibitory properties of N-phenyl- and N-benzyl-substituted amides of 2-(4-methylsulfonylphenyl)cyclopent-1-ene-1-carboxylic acid and of their pyrazole, thiophene and isoxazole analogs. 2004 Jan 1
13 15084117 Synthesis and selective cyclooxygenase-2 inhibitory activity of a series of novel, nitric oxide donor-containing pyrazoles. 2004 Apr 22 2
14 15293263 QSAR analysis of some fused pyrazoles as selective cyclooxygenase-2 inhibitors: a Hansch approach. 2004 Aug 1
15 15521372 Safety of the new selective cyclooxygenase type 2 inhibitors rofecoxib and celecoxib in patients with anaphylactoid reactions to nonsteroidal anti-inflammatory drugs. 2004 Oct 1
16 12620660 Synthesis of heteroaromatic analogues of (2-aryl-1-cyclopentenyl-1-alkylidene)-(arylmethyloxy)amine COX-2 inhibitors: effects on the inhibitory activity of the replacement of the cyclopentene central core with pyrazole, thiophene or isoxazole ring. 2003 Feb 1
17 10741562 1,3-Diarylcycloalkanopyrazoles and diphenyl hydrazides as selective inhibitors of cyclooxygenase-2. 2000 Mar 20 1