beta-Naphthoflavone

cytochrome P450 family 1 subfamily A member 2 ; Homo sapiens







23 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 30592088 The development and prevalidation of an in vitro mutagenicity assay based on MutaMouse primary hepatocytes, Part I: Isolation, structural, genetic, and biochemical characterization. 2019 May 1
2 31569378 The Selection and Validation of Reference Genes for mRNA and microRNA Expression Studies in Human Liver Slices Using RT-qPCR. 2019 Sep 28 1
3 25218365 Diversified expression of aryl hydrocarbon receptor dependent genes in human laryngeal squamous cell carcinoma cell lines treated with β-naphthoflavone. 2014 Nov 18 1
4 20460162 HepaRG human hepatic cell line utility as a surrogate for primary human hepatocytes in drug metabolism assessment in vitro. 2011 Jan-Feb 1
5 21741702 Galactosylated cellulosic sponge for multi-well drug safety testing. 2011 Oct 1
6 20583967 A multi-endpoint evaluation of cytochrome P450 1A2, 2B6 and 3A4 induction response in human hepatocyte cultures after treatment with β-naphthoflavone, phenobarbital and rifampicin. 2010 Dec 1
7 19881256 Evaluation of induction potency of new drug candidates on CYP1A2 and CYP3A4 using real-time one-step RT-PCR in primary cultures of cryopreserved human hepatocytes. 2009 2
8 18502397 Omeprazole transactivates human CYP1A1 and CYP1A2 expression through the common regulatory region containing multiple xenobiotic-responsive elements. 2008 Jul 1 1
9 18989830 Efficient assessment of the utility of immortalized Fa2N-4 cells for cytochrome P450 (CYP) induction studies using multiplex quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR) and substrate cassette methodologies. 2008 Dec 1
10 17531195 Hepatocytes maintain their function on basement membrane formed by epithelial cells. 2007 Jul 20 1
11 17220562 Evaluation of human CYP1A2 and CYP3A4 mRNA expression in hepatocytes from chimeric mice with humanized liver. 2006 Dec 1
12 14722322 Induction of drug metabolism enzymes and MDR1 using a novel human hepatocyte cell line. 2004 Apr 1
13 15364537 The effects of gender, age, ethnicity, and liver cirrhosis on cytochrome P450 enzyme activity in human liver microsomes and inducibility in cultured human hepatocytes. 2004 Sep 15 1
14 12623754 Time-dependent transcriptional induction of CYP1A1, CYP1A2 and CYP1B1 mRNAs by H+/K+ -ATPase inhibitors and other xenobiotics. 2003 Feb 1
15 12642468 Effects of prototypical microsomal enzyme inducers on cytochrome P450 expression in cultured human hepatocytes. 2003 Apr 1
16 12843640 Effects of dimethyl sulfoxide on the gene induction of cytochrome P450 isoforms, UGT-dependent glucuronosyl transferase isoforms, and ABCB1 in primary culture of human hepatocytes. 2003 Jul 1
17 14599235 Cryopreserved human hepatocytes as alternative in vitro model for cytochrome p450 induction studies. 2003 Jul-Aug 1
18 12147246 Characterization of human CYP1A1/1A2 induction by DNA microarray and alpha-naphthoflavone. 2002 Aug 9 1
19 10923861 Expression and induction of CYP1A1/1A2, CYP2A6 and CYP3A4 in primary cultures of human hepatocytes: a 10-year follow-up. 2000 Jun 1
20 10936227 Evidence for cytochrome P4501A2-mediated protein covalent binding of thiabendazole and for its passive intestinal transport: use of human and rabbit derived cells. 2000 Jul 3 1
21 7557864 Differential effects of cytokines on the inducible expression of CYP1A1, CYP1A2, and CYP3A4 in human hepatocytes in primary culture. 1995 Oct 2
22 7811300 Pretranslational induction of cytochrome P4501A enzymes by beta-naphthoflavone and 3-methylcholanthrene occurs in different liver zones. 1994 Dec 16 2
23 4015401 Covalent binding of BP-metabolites to DNA of cultured human hair follicle keratinocytes. 1985 Apr 1