Flavonoids

cytochrome P450 family 1 subfamily A member 2 ; Homo sapiens







23 Article(s)
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1 30048196 Site-specific oxidation of flavanone and flavone by cytochrome P450 2A6 in human liver microsomes. 2019 Jul 1
2 31480528 The Effect of Flavonoid Aglycones on the CYP1A2, CYP2A6, CYP2C8 and CYP2D6 Enzymes Activity. 2019 Sep 1 3
3 31639084 Screening of flavonoid aglycons' metabolism mediated by the human liver cytochromes P450. 2019 Dec 1 1
4 26757127 Role of dihydromyricetin in cytochrome P450-mediated metabolism and carcinogen activation. 2015 2
5 20806393 Differential mechanisms for the inhibition of human cytochrome P450 1A2 by apigenin and genistein. 2010 Jul-Aug 3
6 19034627 Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug-metabolizing enzymes through pregnane X receptor, constitutive androstane receptor, and aryl hydrocarbon receptor-mediated pathways. 2009 Apr 1
7 19215233 Simultaneous action of the flavonoid quercetin on cytochrome P450 (CYP) 1A2, CYP2A6, N-acetyltransferase and xanthine oxidase activity in healthy volunteers. 2009 Aug 1
8 19666078 CYP1-mediated antiproliferative activity of dietary flavonoids in MDA-MB-468 breast cancer cells. 2009 Oct 29 1
9 19012573 Comparative QSAR studies of CYP1A2 inhibitor flavonoids using 2D and 3D descriptors. 2008 Nov 2
10 19244749 [Inhibition of human cytochrome P-450 CYP1A2 by flavonoids: a quantitative structure-activity relationship study ]. 2008 Dec 2
11 15914008 Theoretical quantitative structure-activity relationships of flavone ligands interacting with cytochrome P450 1A1 and 1A2 isozymes. 2005 Jul 15 2
12 16276964 Effects of hydroxyl group numbers on the B-ring of 5,7-dihydroxyflavones on the differential inhibition of human CYP 1A and CYP1B1 enzymes. 2005 Oct 1
13 16789892 Computational insight into anti-mutagenic properties of CYP1A flavonoid ligands. 2005 Jul 1
14 14698415 Biphasic effects of the flavonoids quercetin and naringenin on the metabolic activation of 2-amino-3,5-dimethylimidazo[4,5-f]quinoline by Salmonella typhimurium TA1538 co-expressing human cytochrome P450 1A2, NADPH-cytochrome P450 reductase, and cytochrome b5. 2004 Jan 12 1
15 12828569 In vitro metabolism of genistein and tangeretin by human and murine cytochrome P450s. 2003 Jul 1
16 11936218 Effects of flavonoids isolated from Scutellariae radix on cytochrome P-450 activities in human liver microsomes. 2002 Mar 2
17 11955666 In vitro investigation of cytochrome P450-mediated metabolism of dietary flavonoids. 2002 May 5
18 10620351 Differential effects of flavonoid compounds on tumor promoter-induced activation of the human CYP1A2 enhancer. 2000 Jan 1 1
19 10752639 In vitro inhibition of human P450 enzymes by prenylated flavonoids from hops, Humulus lupulus. 2000 Mar 1
20 10871299 Inhibition of human cytochrome P450 enzymes by constituents of St. John's Wort, an herbal preparation used in the treatment of depression. 2000 Jul 1
21 9718089 Inhibition of methoxyresorufin demethylase activity by flavonoids in human liver microsomes. 1998 1
22 10076527 Structure-related inhibition of human hepatic caffeine N3-demethylation by naturally occurring flavonoids. 1998 May 1 2
23 8155716 Isozyme- and species-specific susceptibility of cDNA-expressed CYP1A P-450s to different flavonoids. 1994 Apr 13 1