Proline

proline dehydrogenase 1 ; Homo sapiens







71 Article(s)
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1 35018940 Structure-affinity relationships of reversible proline analog inhibitors targeting proline dehydrogenase. 2022 Jan 26 6
2 35163433 Nonsteroidal Anti-Inflammatory Drugs as PPARĪ³ Agonists Can Induce PRODH/POX-Dependent Apoptosis in Breast Cancer Cells: New Alternative Pathway in NSAID-Induced Apoptosis. 2022 Jan 28 4
3 35216470 Proline Dehydrogenase/Proline Oxidase (PRODH/POX) Is Involved in the Mechanism of Metformin-Induced Apoptosis in C32 Melanoma Cell Line. 2022 Feb 21 4
4 33646427 Reprogramming of mitochondrial proline metabolism promotes liver tumorigenesis. 2021 Dec 4
5 33818628 Collagen metabolism as a regulator of proline dehydrogenase/proline oxidase-dependent apoptosis/autophagy. 2021 Dec 4
6 34067570 L-Proline Activates Mammalian Target of Rapamycin Complex 1 and Modulates Redox Environment in Porcine Trophectoderm Cells. 2021 May 17 2
7 34085157 Proline oxidase silencing inhibits p53-dependent apoptosis in MCF-7 breast cancer cells. 2021 Dec 3
8 34283310 Proline dehydrogenase in cancer: apoptosis, autophagy, nutrient dependency and cancer therapy. 2021 Dec 2
9 34390414 Proline metabolism in cancer. 2021 Dec 1
10 34577574 PRODH/POX-Dependent Celecoxib-Induced Apoptosis in MCF-7 Breast Cancer. 2021 Aug 29 2
11 34682765 Troglitazone-Induced PRODH/POX-Dependent Apoptosis Occurs in the Absence of Estradiol or ERĪ² in ER-Negative Breast Cancer Cells. 2021 Oct 10 4
12 34752700 Evidence for Proline Catabolic Enzymes in the Metabolism of Thiazolidine Carboxylates. 2021 Nov 30 7
13 34769188 P5C as an Interface of Proline Interconvertible Amino Acids and Its Role in Regulation of Cell Survival and Apoptosis. 2021 Oct 29 2
14 34943229 Understanding the Role of Estrogen Receptor Status in PRODH/POX-Dependent Apoptosis/Survival in Breast Cancer Cells. 2021 Dec 10 8
15 31933109 Understanding the role of key amino acids in regulation of proline dehydrogenase/proline oxidase (prodh/pox)-dependent apoptosis/autophagy as an approach to targeted cancer therapy. 2020 Mar 10
16 32159324 Covalent Modification of the Flavin in Proline Dehydrogenase by Thiazolidine-2-Carboxylate. 2020 Apr 17 8
17 32213586 Oncogenic human herpesvirus hijacks proline metabolism for tumorigenesis. 2020 Apr 7 3
18 32710395 A novel plausible mechanism of NSAIDs-induced apoptosis in cancer cells: the implication of proline oxidase and peroxisome proliferator-activated receptor. 2020 Oct 1
19 32918543 Overexpression of Prolidase Induces Autophagic Death in MCF-7 Breast Cancer Cells. 2020 Sep 12 4
20 33083024 The Janus-like role of proline metabolism in cancer. 2020 1
21 33294127 Metabolomic Analysis of the Ameliorative Effect of Enhanced Proline Metabolism on Hypoxia-Induced Injury in Cardiomyocytes. 2020 5
22 33424902 Appropriate Activity Assays Are Crucial for the Specific Determination of Proline Dehydrogenase and Pyrroline-5-Carboxylate Reductase Activities. 2020 2
23 28990412 Structural Biology of Proline Catabolic Enzymes. 2019 Feb 1 5
24 31229682 Riluzole effectively treats psychotic symptoms and improves cognition in 22q11.2 deletion syndrome: A clinical case. 2019 Aug 2
25 31559416 HDAC inhibitors induce proline dehydrogenase (POX) transcription and anti-apoptotic autophagy in triple negative breast cancer. 2019 Sep 6 2
26 29568391 Proline oxidase silencing induces proline-dependent pro-survival pathways in MCF-7 cells. 2018 Mar 2 1
27 29648801 The Proline Cycle As a Potential Cancer Therapy Target. 2018 Jun 26 6
28 29681859 Constituents of Propolis: Chrysin, Caffeic Acid, p-Coumaric Acid, and Ferulic Acid Induce PRODH/POX-Dependent Apoptosis in Human Tongue Squamous Cell Carcinoma Cell (CAL-27). 2018 3
29 28492237 Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells. 2017 May 11 2
30 28712849 Structure, function, and mechanism of proline utilization A (PutA). 2017 Oct 15 1
31 28863383 Acetylenic derivative of betulin induces apoptosis in endometrial adenocarcinoma cell line. 2017 Nov 4
32 28942439 Functional Consequences of Intracellular Proline Levels Manipulation Affecting PRODH/POX-Dependent Pro-Apoptotic Pathways in a Novel in Vitro Cell Culture Model. 2017 10
33 27040799 Prolidase-proline dehydrogenase/proline oxidase-collagen biosynthesis axis as a potential interface of apoptosis/autophagy. 2016 Jul 8 5
34 27622935 Evidence that COMT genotype and proline interact on negative-symptom outcomes in schizophrenia and bipolar disorder. 2016 Sep 13 1
35 25569235 Insight in genome-wide association of metabolite quantitative traits by exome sequence analyses. 2015 Jan 1
36 25666758 Genome-wide association study of NMDA receptor coagonists in human cerebrospinal fluid and plasma. 2015 Dec 2
37 26055684 Glutamatergic markers, age, intellectual functioning and psychosis in 22q11 deletion syndrome. 2015 Sep 1
38 26161086 Dynamic proline metabolism: importance and regulation in water limited environments. 2015 4
39 26330555 A Novel Role of Proline Oxidase in HIV-1 Envelope Glycoprotein-induced Neuronal Autophagy. 2015 Oct 16 2
40 26553010 Proline Oxidase (POX) as A Target for Cancer Therapy. 2015 1
41 26598224 Proline biosynthesis augments tumor cell growth and aerobic glycolysis: involvement of pyridine nucleotides. 2015 Nov 24 2
42 24787057 Vitamin D insufficiency and schizophrenia risk: evaluation of hyperprolinemia as a mediator of association. 2014 Jun 2
43 25184115 Sources of superoxide/H2O2 during mitochondrial proline oxidation. 2014 1
44 23232983 Metabolomic analysis of dynamic response and drug resistance of gastric cancer cells to 5-fluorouracil. 2013 Mar 1
45 23462603 Identification of PRODH mutations in Korean neonates with type I hyperprolinemia. 2013 Winter 1
46 23861960 P53 family members modulate the expression of PRODH, but not PRODH2, via intronic p53 response elements. 2013 3
47 22089387 L-proline dehydrogenases in hyperthermophilic archaea: distribution, function, structure, and application. 2012 Jan 1
48 22201764 Proline dehydrogenase: a key enzyme in controlling cellular homeostasis. 2012 Jan 1 1
49 22609800 Proline oxidase promotes tumor cell survival in hypoxic tumor microenvironments. 2012 Jul 15 3
50 22615405 Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC. 2012 Jun 5 2