Amidines

coagulation factor X ; Homo sapiens







8 Article(s)
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1 21995444 Discovery of N-[2-hydroxy-6-(4-methoxybenzamido)phenyl]-4- (4-methyl-1,4-diazepan-1-yl)benzamide (darexaban, YM150) as a potent and orally available factor Xa inhibitor. 2011 Dec 8 1
2 12540235 Human factor Xa bound amidine inhibitor conformation by double rotational-echo double resonance nuclear magnetic resonance and molecular dynamics simulations. 2003 Jan 30 1
3 12732352 Discovery and characterization of a potent and selective non-amidine inhibitor of human factor Xa. 2003 May 1 1
4 12036356 Design, synthesis, and activity of a novel series of factor Xa inhibitors: optimization of arylamidine groups. 2002 Jun 6 2
5 12501180 Crystal structures of two potent nonamidine inhibitors bound to factor Xa. 2002 Dec 31 2
6 10715155 Structure-based design of potent, amidine-derived inhibitors of factor Xa: evaluation of selectivity, anticoagulant activity, and antithrombotic activity. 2000 Mar 9 4
7 10841787 Non-amidine-containing 1,2-dibenzamidobenzene inhibitors of human factor Xa with potent anticoagulant and antithrombotic activity. 2000 Jun 1 1
8 10639283 Synthesis, characterization, and structure-activity relationships of amidine-substituted (bis)benzylidene-cycloketone olefin isomers as potent and selective factor Xa inhibitors. 1999 Dec 30 2