Serine

mitogen activated protein kinase 3 ; Rattus norvegicus







35 Article(s)
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1 35413282 Sprouty and Spred temporally regulate ERK1/2-signaling to suppress TGFβ-induced lens EMT. 2022 Jun 1
2 33811247 Sublytic C5b-9 induces glomerular mesangial cell proliferation via ERK1/2-dependent SOX9 phosphorylation and acetylation by enhancing Cyclin D1 in rat Thy-1 nephritis. 2021 Apr 1
3 30648910 Blockade of ERK1/2 by U0126 alleviates uric acid-induced EMT and tubular cell injury in rats with hyperuricemic nephropathy. 2019 Apr 1 2
4 30716553 Optimized liposomes with transactivator of transcription peptide and anti-apoptotic drugs to target hippocampal neurons and prevent tau-hyperphosphorylated neurodegeneration. 2019 Mar 15 1
5 28821999 Developmental neurotoxicity of the hippocampus following in utero exposure to methylmercury: impairment in cell signaling. 2018 Jan 1
6 28057484 Type II cGMP-dependent protein kinase negatively regulates fibroblast growth factor signaling by phosphorylating Raf-1 at serine 43 in rat chondrosarcoma cells. 2017 Jan 29 1
7 26929437 High-fat diet increases O-GlcNAc levels in cerebral arteries: a link to vascular dysfunction associated with hyperlipidaemia/obesity? 2016 Jun 1 2
8 26468734 Co-activator binding protein PIMT mediates TNF-α induced insulin resistance in skeletal muscle via the transcriptional down-regulation of MEF2A and GLUT4. 2015 Oct 15 1
9 24582310 Mitochondrial STAT3 plays a major role in IgE-antigen-mediated mast cell exocytosis. 2014 Aug 1
10 24358311 ERK2-mediated phosphorylation of transcriptional coactivator binding protein PIMT/NCoA6IP at Ser298 augments hepatic gluconeogenesis. 2013 1
11 22957439 The Raf-1 inhibitor GW5074 and the ERK1/2 pathway inhibitor U0126 ameliorate PC12 cells apoptosis induced by 6-hydroxydopamine. 2012 Aug 3
12 23251488 Endogenous repair by the activation of cell survival signalling cascades during the early stages of rat Parkinsonism. 2012 1
13 21168220 SOCS3 suppresses the expression of IL-4 cytokine by inhibiting the phosphorylation of c-Jun through the ERK signaling pathway in rat mast cell line RBL-2H3. 2011 Feb 1
14 20547636 Endothelial regulation of eNOS, PAI-1 and t-PA by testosterone and dihydrotestosterone in vitro and in vivo. 2010 Oct 1
15 18187403 cPLA2 phosphorylation at serine-515 and serine-505 is required for arachidonic acid release in vascular smooth muscle cells. 2008 Apr 1
16 18375950 A direct redox regulation of protein kinase C isoenzymes mediates oxidant-induced neuritogenesis in PC12 cells. 2008 May 23 1
17 18598691 Repeated cocaine administration increases N-methyl-d-aspartate NR1 subunit, extracellular signal-regulated kinase and cyclic AMP response element-binding protein phosphorylation and glutamate release in the rat dorsal striatum. 2008 Aug 20 2
18 18824646 Functionally opposing roles of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase in the regulation of cardiac contractility. 2008 Oct 14 1
19 16806261 PKA-mediated ERK1/2 inactivation and hsp70 gene expression following exercise. 2006 Nov 1
20 16940436 Growth retardation alters the epigenetic characteristics of hepatic dual specificity phosphatase 5. 2006 Oct 2
21 15921682 ERK1/2 activation by angiotensin II inhibits insulin-induced glucose uptake in vascular smooth muscle cells. 2005 Aug 15 1
22 12937126 Okadaic-acid-induced inhibition of protein phosphatase 2A produces activation of mitogen-activated protein kinases ERK1/2, MEK1/2, and p70 S6, similar to that in Alzheimer's disease. 2003 Sep 1
23 11916914 Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation. 2002 Apr 1
24 12048211 Role of MAP kinases in the 1,25-dihydroxyvitamin D3-induced transactivation of the rat cytochrome P450C24 (CYP24) promoter. Specific functions for ERK1/ERK2 and ERK5. 2002 Aug 16 1
25 12099715 Phenylephrine promotes phosphorylation of Bad in cardiac myocytes through the extracellular signal-regulated kinases 1/2 and protein kinase A. 2002 Jul 4
26 11297520 Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth. 2001 Jun 1 1
27 10084688 NCAM stimulates the Ras-MAPK pathway and CREB phosphorylation in neuronal cells. 1999 Mar 1
28 9592082 Mitogen-activated protein kinases (Erk1,2) phosphorylate Lys-Ser-Pro (KSP) repeats in neurofilament proteins NF-H and NF-M. 1998 Jun 1 1
29 9126327 Elevated amyloid beta protein(1-40) level induces CREB phosphorylation at serine-133 via p44/42 MAP kinase (Erk1/2)-dependent pathway in rat pheochromocytoma PC12 cells. 1997 Mar 27 5
30 8197172 Protein-tyrosine-phosphatase 2C is phosphorylated and inhibited by 44-kDa mitogen-activated protein kinase. 1994 May 24 1
31 1347949 ERK1 and ERK2, two microtubule-associated protein 2 kinases, mediate the phosphorylation of tyrosine hydroxylase at serine-31 in situ. 1992 Mar 15 1
32 1627831 Extracellular signal-regulated kinases 2 autophosphorylates on a subset of peptides phosphorylated in intact cells in response to insulin and nerve growth factor: analysis by peptide mapping. 1992 Mar 1
33 1645334 pp54 microtubule-associated protein-2 kinase requires both tyrosine and serine/threonine phosphorylation for activity. 1991 Jun 5 1
34 1672814 Identification of a major maturation-activated acetyl-CoA carboxylase kinase in sea star oocytes as p44mpk. 1991 Mar 15 1
35 1717989 Mouse Erk-1 gene product is a serine/threonine protein kinase that has the potential to phosphorylate tyrosine. 1991 Oct 1 1