Sulfhydryl Compounds

glutathione-disulfide reductase ; Homo sapiens







38 Article(s)
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Pub. Year
#Total Relationships
1 31521661 A review on the druggability of a thiol-based enzymatic antioxidant thioredoxin reductase for treating filariasis and other parasitic infections. 2020 Jan 1 1
2 32961182 Thiol antioxidant thioredoxin reductase: A prospective biochemical crossroads between anticancer and antiparasitic treatments of the modern era. 2020 Dec 15 2
3 33409268 Assessing the Covalent Attachment and Energy Transfer Capabilities of Upconverting Phosphors With Cofactor Containing Bioactive Enzymes. 2020 1
4 30654300 Electrophiles modulate glutathione reductase activity via alkylation and upregulation of glutathione biosynthesis. 2019 Feb 1
5 28461233 Inhibition of reductase systems by 2-AAPA modulates peroxiredoxin oxidation and mitochondrial function in A172 glioblastoma cells. 2017 Aug 1
6 28977909 2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylcarbonylamino) phenyl carbamoylsulfanyl] propionic acid, a glutathione reductase inhibitor, induces G2/M cell cycle arrest through generation of thiol oxidative stress in human esophageal cancer cells. 2017 Sep 22 2
7 26923386 The role of glutathione reductase and related enzymes on cellular redox homoeostasis network. 2016 Jun 1
8 27054760 Unexpected Thiols Triggering Photoluminescent Enhancement of Cytidine Stabilized Au Nanoclusters for Sensitive Assays of Glutathione Reductase and Its Inhibitors Screening. 2016 May 3 1
9 25645953 Reduction of mitochondrial protein mitoNEET [2Fe-2S] clusters by human glutathione reductase. 2015 Apr 1
10 23396001 Trypanothione: a unique bis-glutathionyl derivative in trypanosomatids. 2013 May 1
11 23792825 Glutathione and glutathione reductase: a boon in disguise for plant abiotic stress defense operations. 2013 Sep 2
12 24115172 Proteomic and redox-proteomic study on the role of glutathione reductase in human lung cancer cells. 2013 Dec 1
13 22202809 Disruption of a glutathione reductase encoding gene in Acremonium chrysogenum leads to reduction of its growth, cephalosporin production and antioxidative ability which is recovered by exogenous methionine. 2012 Feb 1
14 22247548 Five decades with glutathione and the GSTome. 2012 Feb 24 1
15 21443269 Susceptibility of the antioxidant selenoenyzmes thioredoxin reductase and glutathione peroxidase to alkylation-mediated inhibition by anticancer acylfulvenes. 2011 May 16 2
16 21992226 Triggered cargo release by encapsulated enzymatic catalysis in capsosomes. 2011 Nov 9 1
17 21072382 Cysteine proteases as targets for metal-based drugs. 2010 Jun 1
18 19272349 Effects of glutathione reductase inhibition on cellular thiol redox state and related systems. 2009 May 1 2
19 19336037 A novel vanadium reductase, Vanabin2, forms a possible cascade involved in electron transfer. 2009 Apr 1
20 19388016 A highly sensitive fluorescence probe for fast thiol-quantification assay of glutathione reductase. 2009 1
21 19397999 Increase in thiol oxidative stress via glutathione reductase inhibition as a novel approach to enhance cancer sensitivity to X-ray irradiation. 2009 Jul 15 1
22 18166048 Harnessing the mechanism of glutathione reductase for synthesis of active site bound metallic nanoparticles and electrical connection to electrodes. 2008 Jan 23 1
23 17514531 Revival of glutathione reductase in human cataractous and clear lens extracts by thioredoxin and thioredoxin reductase, in conjunction with alpha-crystallin or thioltransferase. 2007 May 2
24 15792952 Mechanistic studies on a novel, highly potent gold-phosphole inhibitor of human glutathione reductase. 2005 May 27 2
25 12171583 Enzymes of the trypanothione metabolism as targets for antitrypanosomal drug development. 2002 Nov 1
26 10900126 Minor thiols cysteine and cysteinylglycine regulate the competition between glutathione and protein SH groups in human platelets subjected to oxidative stress. 2000 Aug 1 1
27 9508091 Human sperm glutathione reductase activity in situ reveals limitation in the glutathione antioxidant defense system due to supply of NADPH. 1998 Apr 1
28 9821018 Only the glutathione dependent antioxidant enzymes are inhibited by haematotoxic hydroxylamines. 1998 Oct 1
29 9076692 Gaining more insight into the pathomechanisms of thiol-induced acantholysis. 1997 Feb 1
30 9393673 Dinitrosyl-dithiol-iron complexes, nitric oxide (NO) carriers in vivo, as potent inhibitors of human glutathione reductase and glutathione-S-transferase. 1997 Dec 15 1
31 8103788 Cellular oxidation of low density lipoprotein is caused by thiol production in media containing transition metal ions. 1993 Jul 1
32 1443795 [Optimization of a spectrophotometry assay of total and oxidized blood glutathione: comparison with a fluorimetric method]. 1992 1
33 2171674 1H-nuclear magnetic resonance study of the oxidation/reduction chemistry of penicillamine in intact human erythrocytes. 1990 Oct 15 1
34 2499573 Isolation and sequence studies of cysteinyl peptides from Spirulina glutathione reductase: comparison of active site cysteine peptides with those of other flavoprotein disulfide oxidoreductases. 1989 Mar 1
35 2709339 Glutathione in Tetrahymena thermophila. 1989 Jan-Feb 1
36 2848577 Glutathione reductase: solvent equilibrium and kinetic isotope effects. 1988 Sep 6 1
37 3987692 FAD analogues as prosthetic groups of human glutathione reductase. Properties of the modified enzyme species and comparisons with the active site structure. 1985 Apr 15 1
38 6810885 Copper inhibition of glutathione reductase and its reversal with gold thiolates, thiol, and disulfide compounds. 1982 Jun 1