cupric ion

amyloid beta precursor protein ; Homo sapiens







87 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34932369 Effect of Surface-Chelated Cu2+ on Amyloid-β Peptide Fibrillation. 2022 Jan 11 5
2 35080861 Semax, a Synthetic Regulatory Peptide, Affects Copper-Induced Abeta Aggregation and Amyloid Formation in Artificial Membrane Models. 2022 Feb 16 3
3 35101650 Synthesis, biological evaluation, and molecular modeling simulations of new heterocyclic hybrids as multi-targeted anti-Alzheimer's agents. 2022 Mar 5 1
4 35468173 A dual-mechanism-driven electrochemiluminescence aptasensor for sensitive detection of β-amyloid peptides. 2022 May 5 12
5 33208229 Binding of Cu2+ to Aβ1-29 causes aggregation and toxicity in SH-SY5Y cells. 2021 Jan 1 1
6 33326534 Cu2+-binding to S100B triggers polymerization of disulfide cross-linked tetramers with enhanced chaperone activity against amyloid-β aggregation. 2021 Jan 14 1
7 33401892 Molecular Insight into Cu2+-Induced Conformational Transitions of Amyloid β-Protein from Fast Kinetic Analysis and Molecular Dynamics Simulations. 2021 Jan 20 5
8 33405903 A Cu-bis(imidazole) Substrate Intermediate Is the Catalytically Competent Center for Catechol Oxidase Activity of Copper Amyloid-β. 2021 Jan 18 1
9 33588277 Copper (II) binding properties of an octapeptide fragment from the R3 region of tau protein: A combined potentiometric, spectroscopic and mass spectrometric study. 2021 Apr 1
10 34068879 Oxidase Reactivity of CuII Bound to N-Truncated Aβ Peptides Promoted by Dopamine. 2021 May 14 1
11 34202166 A Novel Cu(II)-Binding Peptide Identified by Phage Display Inhibits Cu2+-Mediated Aβ Aggregation. 2021 Jun 25 2
12 34450410 Inhibition of Aβ peptide aggregation by ruthenium(II) polypyridyl complexes through copper chelation. 2021 Nov 5
13 34510664 A Water-Soluble Peptoid Chelator that Can Remove Cu2+ from Amyloid-β Peptides and Stop the Formation of Reactive Oxygen Species Associated with Alzheimer's Disease. 2021 Nov 8 1
14 34812903 Interactions between copper (II) and β-amyloid peptide using capillary electrophoresis-ICP-MS: Kd measurements at the nanogram scale. 2021 Nov 23 2
15 32100783 Conjugation of RTHLVFFARK to human lysozyme creates a potent multifunctional modulator for Cu2+-mediated amyloid β-protein aggregation and cytotoxicity. 2020 Mar 21 11
16 32297620 Peroxidase activity of heme bound amyloid β peptides associated with Alzheimer's disease. 2020 Apr 28 1
17 32343975 Copper-induced spectroscopic and structural changes in short peptides derived from azurin. 2020 Jul 15 1
18 32570820 Redox-Dependent Copper Ion Modulation of Amyloid-β (1-42) Aggregation In Vitro. 2020 Jun 18 1
19 32775897 Rhodamine-Based Metal Chelator: A Potent Inhibitor of Metal-Catalyzed Amyloid Toxicity. 2020 Aug 4 2
20 33137558 Inhibition of Aβ aggregates in Alzheimer's disease by epigallocatechin and epicatechin-3-gallate from green tea. 2020 Dec 2
21 30650306 d-Enantiomeric RTHLVFFARK-NH2: A Potent Multifunctional Decapeptide Inhibiting Cu2+-Mediated Amyloid β-Protein Aggregation and Remodeling Cu2+-Mediated Amyloid β Aggregates. 2019 Mar 20 2
22 30685090 The binding of monomeric amyloid β peptide to serum albumin is affected by major plasma unsaturated fatty acids. 2019 Mar 5 1
23 30849487 A comprehensive study on the generation of reactive oxygen species in Cu-Aβ-catalyzed redox processes. 2019 May 1 1
24 31005822 Metal-dependent interactions of metallothionein-3 β-domain with amyloid-β peptide and related physiological implications. 2019 Jul 3
25 31254862 A label-free and signal-on electrochemiluminescence strategy for sensitive amyloid-beta assay. 2019 Sep 15 3
26 29192759 Sulfur Nanoparticles with Novel Morphologies Coupled with Brain-Targeting Peptides RVG as a New Type of Inhibitor Against Metal-Induced Aβ Aggregation. 2018 Apr 18 1
27 29318655 Design of nonapeptide LVFFARKHH: A bifunctional agent against Cu2+ -mediated amyloid β-protein aggregation and cytotoxicity. 2018 Jun 4
28 29774745 Interplay between Copper, Neprilysin, and N-Truncation of β-Amyloid. 2018 Jun 4 2
29 30213975 Copper mediated amyloid-β binding to Transthyretin. 2018 Sep 13 2
30 30385800 Copper Redox Cycling Inhibits Aβ Fibre Formation and Promotes Fibre Fragmentation, while Generating a Dityrosine Aβ Dimer. 2018 Nov 1 3
31 28069584 Role of norepinephrine in Aβ-related neurotoxicity: dual interactions with Tyr10 and SNK(26-28) of Aβ. 2017 Feb 6 1
32 28621929 Kinetic Analysis Reveals the Identity of Aβ-Metal Complex Responsible for the Initial Aggregation of Aβ in the Synapse. 2017 Sep 20 8
33 26928943 Molecular Simulations of Human and Mouse Aβ1-16 at Different pH Values: Structural Characteristics toward Understanding Cu(2+) -Coordinated Amyloid Beta Spheres. 2016 Jun 3 1
34 27355515 Natural Tripeptide-Based Inhibitor of Multifaceted Amyloid β Toxicity. 2016 Sep 21 3
35 27616333 Copper Ion Binding Site in β-Amyloid Peptide. 2016 Oct 12 1
36 27619837 Gold nanoparticle-capped mesoporous silica-based H2O2-responsive controlled release system for Alzheimer's disease treatment. 2016 Dec 2
37 27687332 Complicated function of dopamine in Aβ-related neurotoxicity: Dual interactions with Tyr10 and SNK(26-28) of Aβ. 2016 Nov 1
38 32264608 An ultrathin graphitic carbon nitride nanosheet: a novel inhibitor of metal-induced amyloid aggregation associated with Alzheimer's disease. 2016 Jun 21 1
39 25529008 Introduction of a fluorescent probe to amyloid-β to reveal kinetic insights into its interactions with copper(II). 2015 Jan 19 2
40 25597800 Development of gold nanoparticle based colorimetric method for quantitatively studying the inhibitors of Cu(2+)/Zn(2+) induced β-amyloid peptide assembly. 2015 Feb 9 1
41 25861567 The Necessity of Having a Tetradentate Ligand to Extract Copper(II) Ions from Amyloids. 2015 Feb 1
42 24523414 Capturing a reactive state of amyloid aggregates: NMR-based characterization of copper-bound Alzheimer disease amyloid β-fibrils in a redox cycle. 2014 Apr 4 4
43 24594588 Effect of C-terminal residues of Aβ on copper binding affinity, structural conversion and aggregation. 2014 3
44 23143330 Nanoprobing of the effect of Cu(2+) cations on misfolding, interaction and aggregation of amyloid β peptide. 2013 Mar 1
45 23174653 pH-dependent kinetics of copper ions binding to amyloid-β peptide. 2013 Feb 1
46 23537393 Mixed ligand Cu2+ complexes of a model therapeutic with Alzheimer's amyloid-β peptide and monoamine neurotransmitters. 2013 Apr 15 1
47 23747389 Amyloid-β peptide (1-42) aggregation induced by copper ions under acidic conditions. 2013 Jul 3
48 23904252 In silico and in vitro studies to elucidate the role of Cu2+ and galanthamine as the limiting step in the amyloid beta (1-42) fibrillation process. 2013 Oct 1
49 24037720 Characterization of the polymorphic states of copper(II)-bound Aβ(1-16) peptides by computational simulations. 2013 Nov 5 6
50 24274576 Investigation of Cu2+ binding to human and rat amyloid fragments Aβ (1-16) with a protein nanopore. 2013 Dec 17 3