Acetylcholine

amyloid beta precursor protein ; Homo sapiens







39 Article(s)
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Pub. Year
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1 35566132 Nicotinic Acetylcholine Receptors and Microglia as Therapeutic and Imaging Targets in Alzheimer's Disease. 2022 Apr 27 2
2 33252082 Multi-Target Effects of the Cannabinoid CP55940 on Familial Alzheimer's Disease PSEN1 E280A Cholinergic-Like Neurons: Role of CB1 Receptor. 2021 1
3 33571523 Selective coactivation of α7- and α4β2-nicotinic acetylcholine receptors reverses beta-amyloid-induced synaptic dysfunction. 2021 Jan-Jun 1
4 33862141 Integrated phylogeny of the human brain and pathobiology of Alzheimer's disease: A unifying hypothesis. 2021 Jun 11 2
5 34733055 DMSO Delays Alzheimer Disease Causing Aβ-induced Paralysis in C. elegans Through Modulation of Glutamate/Acetylcholine Neurotransmission. 2021 Jan 1
6 32582986 Expression levels of the α7 nicotinic acetylcholine receptor in the brains of patients with Alzheimer's disease and their effect on synaptic proteins in SH-SY5Y cells. 2020 Sep 1
7 33042734 A Novel Targeted and High-Efficiency Nanosystem for Combinational Therapy for Alzheimer's Disease. 2020 Oct 1
8 30800059 Molecular Modulation of Human α7 Nicotinic Receptor by Amyloid-β Peptides. 2019 1
9 31417354 Homomeric and Heteromeric Aβ Species Exist in Human Brain and CSF Regardless of Alzheimer's Disease Status and Risk Genotype. 2019 4
10 31934215 The expression of the nicotinic acetylcholine receptor α3 subunit in the brains of patients with Alzheimer's disease and its effects on α- and γ-secretases and Notch signal transduction in SH-SY5Y cells. 2019 1
11 28993924 Effects of Acetylcholine on β-Amyloid-Induced cPLA2 Activation in the TB Neuroectodermal Cell Line: Implications for the Pathogenesis of Alzheimer's Disease. 2018 May 6
12 27719660 Neuroprotective and Neurotoxic Implications of α7 Nicotinic Acetylcholine Receptor and Aβ Interaction: Therapeutic Options in Alzheimer's Disease. 2017 2
13 28074940 Alpha7 nicotinic acetylcholine receptor is required for amyloid pathology in brain endothelial cells induced by Glycoprotein 120, methamphetamine and nicotine. 2017 Jan 11 1
14 26293308 Immunohistochemical analysis of hippocampal butyrylcholinesterase: Implications for regional vulnerability in Alzheimer's disease. 2016 Apr 1
15 26861273 Novel Triazole-Quinoline Derivatives as Selective Dual Binding Site Acetylcholinesterase Inhibitors. 2016 Feb 5 1
16 27402297 β-Amyloid-acetylcholine molecular interaction: new role of cholinergic mediators in anti-Alzheimer therapy? 2016 Jul 2
17 25004204 Adipose and leptomeningeal arteriole endothelial dysfunction induced by β-amyloid peptide: a practical human model to study Alzheimer's disease vasculopathy. 2014 Sep 30 4
18 23022323 Modeling the binding mechanism of Alzheimer's Aβ1-42 to nicotinic acetylcholine receptors based on similarity with snake α-neurotoxins. 2013 Jan 2
19 23036017 Pathogenesis of Abeta oligomers in synaptic failure. 2013 Mar 1
20 24292188 [Molecular targeting and translational research for new therapeutic strategies on Alzheimer's disease]. 2013 2
21 21683475 Different β-amyloid oligomer assemblies in Alzheimer brains correlate with age of disease onset and impaired cholinergic activity. 2012 Apr 1
22 22261393 Neuronal receptors as targets for the action of amyloid-beta protein (Aβ) in the brain. 2012 Jan 20 1
23 22300028 α7 nicotinic acetylcholine receptors in Alzheimer's disease: neuroprotective, neurotrophic or both? 2012 May 1
24 22402892 Cerebrospinal fluid levels of Aβ42 relationship with cholinergic cortical activity in Alzheimer's disease patients. 2012 Jul 1
25 24052808 Synthesis and in silico evaluation of 1N-methyl-1S-methyl-2-nitroethylene (NMSM) derivatives against Alzheimer disease: to understand their interacting mechanism with acetylcholinesterase. 2012 2
26 21116052 Functional interactions of fibrillar and oligomeric amyloid-β with alpha7 nicotinic receptors in Alzheimer's disease. 2011 1
27 20847424 Amyloid-β as a modulator of synaptic plasticity. 2010 1
28 19355845 M1 agonists as a potential disease-modifying therapy for Alzheimer's disease. 2009 Apr 1
29 19726654 Dissociating beta-amyloid from alpha 7 nicotinic acetylcholine receptor by a novel therapeutic agent, S 24795, normalizes alpha 7 nicotinic acetylcholine and NMDA receptor function in Alzheimer's disease brain. 2009 Sep 2 1
30 17007734 Neuronal nicotinic acetylcholine receptors serve as sensitive targets that mediate beta-amyloid neurotoxicity. 2006 Oct 1
31 15599613 The acetylcholine innervation of cerebral cortex: new data on its normal development and its fate in the hAPP(SW,IND) mouse model of Alzheimer's disease. 2005 Jan 1
32 15544502 An overview of the current and novel drugs for Alzheimer's disease with particular reference to anti-cholinesterase compounds. 2004 1
33 12557749 Amyloid beta-peptide 25-35 reduces [3H]acetylcholine release in retinal neurons. Involvement of metabolic dysfunction. 2002 Dec 3
34 10771022 Modulation of beta-amyloid precursor protein processing and tau phosphorylation by acetylcholine receptors. 2000 Mar 30 1
35 9562476 Possible role of tau protein kinases in pathogenesis of Alzheimer's disease. 1998 Jan-Feb 1
36 9335413 Beta-amyloid-induced coronary artery vasoactivity and endothelial damage. 1997 Oct 1
37 8651643 A beta-subunit mutation in the acetylcholine receptor channel gate causes severe slow-channel syndrome. 1996 Jun 1
38 8239317 Abnormalities in brain glucose utilization and its impact on cellular and molecular mechanisms in sporadic dementia of Alzheimer type. 1993 Sep 24 1
39 1377855 Amyloid beta protein precursors with kunitz-type inhibitor domains and acetylcholinesterase in cerebrospinal fluid from patients with dementia of the Alzheimer type. 1992 May 1