Lysine

amyloid beta precursor protein ; Homo sapiens







51 Article(s)
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1 35232199 Replica permutation with solute tempering for molecular dynamics simulation and its application to the dimerization of amyloid-β fragments. 2022 Feb 28 1
2 33872013 Protein Footprinting via Covalent Protein Painting Reveals Structural Changes of the Proteome in Alzheimer's Disease. 2021 May 7 1
3 34478776 A mass spectrometric approach to study the interaction of amyloid β peptides with human α-2-macroglobulin. 2021 Dec 1
4 32016207 Substrate interaction inhibits γ-secretase production of amyloid-β peptides. 2020 Feb 27 1
5 32250101 Supramolecular β-Sheet Forming Peptide Conjugated with Near-Infrared Chromophore for Selective Targeting, Imaging, and Dysfunction of Mitochondria. 2020 May 20 1
6 30194628 An In-Silico Investigation of Key Lysine Residues and Their Selection for Clearing off Aβ and Holo-AβPP Through Ubiquitination. 2019 Dec 1
7 30469267 Development of Chemically Signal Amplified Nano-Biosensor Mediated by Poly-L-Lysine. 2019 Mar 1 2
8 30913789 Detection of Amyloid β Using a Poly-L-Lysine Mediated Nanobiosensor. 2019 Aug 1 1
9 29095570 Mechanisms of proton relay and product release by Class A β-lactamase at ultrahigh resolution. 2018 Jan 1
10 28100776 Crystallographic Snapshots of Class A β-Lactamase Catalysis Reveal Structural Changes That Facilitate β-Lactam Hydrolysis. 2017 Mar 10 1
11 28892616 Chemoproteomics-Enabled Covalent Ligand Screening Reveals a Thioredoxin-Caspase 3 Interaction Disruptor That Impairs Breast Cancer Pathogenicity. 2017 Oct 20 1
12 29038915 Glycation of Lys-16 and Arg-5 in amyloid-β and the presence of Cu2+ play a major role in the oxidative stress mechanism of Alzheimer's disease. 2017 Dec 2
13 26994210 Inhibition of Aβ(1-40) fibril formation by cyclophilins. 2016 May 15 1
14 27196068 ABCG1 and ABCG4 Suppress γ-Secretase Activity and Amyloid β Production. 2016 1
15 27929168 A computational study of self-assembled hexapeptide inhibitors against amyloid-β (Aβ) aggregation. 2016 Dec 21 2
16 26175157 Mesotrypsin Has Evolved Four Unique Residues to Cleave Trypsin Inhibitors as Substrates. 2015 Aug 28 1
17 24617810 Turn plasticity distinguishes different modes of amyloid-β aggregation. 2014 Apr 2 1
18 25178721 Sulforaphane interaction with amyloid beta 1-40 peptide studied by electrospray ionization mass spectrometry. 2014 Oct 30 2
19 23033946 Molecular properties of lysine dendrimers and their interactions with Aβ-peptides and neuronal cells. 2013 1
20 23291379 Ethanol reduces amyloid aggregation in vitro and prevents toxicity in cell lines. 2013 Jan 1
21 23401512 Quantitative analysis of the time course of Aβ oligomerization and subsequent growth steps using tetramethylrhodamine-labeled Aβ. 2013 Feb 26 1
22 23904252 In silico and in vitro studies to elucidate the role of Cu2+ and galanthamine as the limiting step in the amyloid beta (1-42) fibrillation process. 2013 Oct 2
23 22200570 Effect of N-homocysteinylation on physicochemical and cytotoxic properties of amyloid β-peptide. 2012 Jan 20 1
24 22207202 Mapping acetylation sites in E2A identifies a conserved lysine residue in activation domain 1 that promotes CBP/p300 recruitment and transcriptional activation. 2012 May 1
25 22267734 Biochemical inhibition of the acetyltransferases ATase1 and ATase2 reduces β-secretase (BACE1) levels and Aβ generation. 2012 Mar 9 1
26 22299711 Lys(203) and Lys(382) are essential for the proteasomal degradation of BACE1. 2012 Jun 2
27 22847417 Ubiquilin-1 regulates amyloid precursor protein maturation and degradation by stimulating K63-linked polyubiquitination of lysine 688. 2012 Aug 14 1
28 21868378 Lysine 624 of the amyloid precursor protein (APP) is a critical determinant of amyloid β peptide length: support for a sequential model of γ-secretase intramembrane proteolysis and regulation by the amyloid β precursor protein (APP) juxtamembrane region. 2011 Nov 18 3
29 21916458 Lysine-specific molecular tweezers are broad-spectrum inhibitors of assembly and toxicity of amyloid proteins. 2011 Oct 26 1
30 18675254 Sumoylation of amyloid precursor protein negatively regulates Abeta aggregate levels. 2008 Oct 3 1
31 18701950 Structural changes of poly-L-lysine in solution and lyophilized form. 2008 Sep 1 1
32 17940047 Familial Alzheimer's disease mutations alter the stability of the amyloid beta-protein monomer folding nucleus. 2007 Oct 16 1
33 16785530 Inhibition of MHC class II expression and immune responses by c-MIR. 2006 Jul 1 1
34 17106577 Histidines 13 and 14 in the Abeta sequence are targets for inhibition of Alzheimer's disease Abeta ion channel and cytotoxicity. 2006 1
35 15837927 Folding events in the 21-30 region of amyloid beta-protein (Abeta) studied in silico. 2005 Apr 26 1
36 16183991 SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling. 2005 Dec 2 1
37 15264846 Poly-L-lysine templated silicas: using polypeptide secondary structure to control oxide pore architectures. 2004 Jul 28 2
38 11866430 Poly-L-lysine dissolves fibrillar aggregation of the Alzheimer beta-amyloid peptide in vitro. 2002 Mar 8 1
39 12395425 pKa, MM, and QM studies of mechanisms of beta-lactamases and penicillin-binding proteins: acylation step. 2002 Dec 1
40 11164277 The region 1-11 of Alzheimer amyloid-beta is critical for activation of contact-kinin system. 2001 Jan-Feb 2
41 11425316 Structure-function relationships for inhibitors of beta-amyloid toxicity containing the recognition sequence KLVFF. 2001 Jul 3 1
42 11438549 Homodimerization of amyloid precursor protein and its implication in the amyloidogenic pathway of Alzheimer's disease. 2001 Sep 7 1
43 11029577 Effect of amino-acid substitutions on Alzheimer's amyloid-beta peptide-glycosaminoglycan interactions. 2000 Nov 2
44 7629198 Proteoglycan-mediated inhibition of A beta proteolysis. A potential cause of senile plaque accumulation. 1995 Aug 4 1
45 7793988 Differential binding of vascular cell-derived proteoglycans (perlecan, biglycan, decorin, and versican) to the beta-amyloid protein of Alzheimer's disease. 1995 Jun 20 3
46 7811262 Proteolysis of A beta peptide from Alzheimer disease brain by gelatinase A. 1994 Dec 30 1
47 8239271 Cellular processing and proteoglycan nature of amyloid precursor proteins. 1993 Sep 24 1
48 1283743 Conformational study of a peptide epitope shows large preferences for beta-turn conformations. 1992 Dec 1
49 2404065 Cell surface expression of hybrid murine/human MHC class II beta alpha dimers. Key influence of residues in the amino-terminal portion of the beta 1 domain. 1990 Jan 1 2
50 6863249 Models for the complexes formed between cytochrome b5 and the subunits of methemoglobin. 1983 Jun 25 1