Oligonucleotides

androgen receptor ; Homo sapiens







52 Article(s)
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1 34740892 Loss of Long Noncoding RNA NXTAR in Prostate Cancer Augments Androgen Receptor Expression and Enzalutamide Resistance. 2022 Jan 1 3
2 35052449 Nucleic Acid-Based Therapeutic Approach for Spinal and Bulbar Muscular Atrophy and Related Neurological Disorders. 2022 Jan 5 1
3 35098567 Delivery of antisense oligonucleotides for splice-correction of androgen receptor pre-mRNA in castration-resistant prostate cancer models using cell-penetrating peptides. 2022 May 1
4 33219721 The long non-coding RNA PCAL7 promotes prostate cancer by strengthening androgen receptor signaling. 2021 Feb 1
5 33335793 A Multifunctional LNA Oligonucleotide-Based Strategy Blocks AR Expression and Transactivation Activity in PCa Cells. 2021 Mar 5 2
6 31940495 Targeting the Oncogenic Long Non-coding RNA SLNCR1 by Blocking Its Sequence-Specific Binding to the Androgen Receptor. 2020 Jan 14 2
7 32934110 Disease mechanism, biomarker and therapeutics for spinal and bulbar muscular atrophy (SBMA). 2020 Oct 1
8 30135193 Epigenetic Reprogramming with Antisense Oligonucleotides Enhances the Effectiveness of Androgen Receptor Inhibition in Castration-Resistant Prostate Cancer. 2018 Oct 15 3
9 28129131 6BIO Enhances Oligonucleotide Activity in Cells: A Potential Combinatorial Anti-androgen Receptor Therapy in Prostate Cancer Cells. 2017 Jan 4 3
10 25634993 Generation 2.5 antisense oligonucleotides targeting the androgen receptor and its splice variants suppress enzalutamide-resistant prostate cancer cell growth. 2015 Apr 1 1
11 24890318 Targeting the androgen receptor in prostate cancer. 2014 Jul 1
12 23554843 Increased expression of the androgen receptor with p300 and interleukin-6 coactivators compensate for oligonucleotide suppression of bcl-2: no increased CREB binding protein or interleukin-4 expression. 2013 Apr 1
13 24169353 First-in-human Phase I study of EZN-4176, a locked nucleic acid antisense oligonucleotide to exon 4 of the androgen receptor mRNA in patients with castration-resistant prostate cancer. 2013 Nov 12 4
14 21869905 In LNCaP cells enhanced expression of the androgen receptor compensates for Bcl-2 suppression by antisense oligonucleotides. 2011 Apr 1
15 22164193 In LNCaP cells enhanced expression of both androgen receptor and costimulatory protein p300 compensate for antisense oligonucleotide suppression of bcl-2. 2011 Dec 1
16 19059367 DNA dependent recruitment of DDX17 and other interacting proteins by the human androgen receptor. 2009 Feb 3
17 19186031 Silencing the androgen receptor: new skills for antiandrogen oligonucleotide skin and hair therapy. 2009 May 1
18 18270197 Activation of the DNA-dependent protein kinase stimulates nuclear export of the androgen receptor in vitro. 2008 Apr 18 1
19 19080333 Inhibition of human prostate cancer xenograft growth by 125I labeled triple-helix forming oligonucleotide directed against androgen receptor. 2008 Nov 20 3
20 19080439 [Effects of anti-gene and antisense therapeutics on human prostate cancer xenograft in nude mice]. 2008 Jul 29 3
21 17326011 Inhibition of the androgen receptor by antisense oligonucleotides regulates the biological activity of androgens in SZ95 sebocytes. 2007 Feb 5
22 17326012 Responsiveness to androgens and effectiveness of antisense oligonucleotides against the androgen receptor on human epidermal keratinocytes is dependent on the age of the donor and the location of cell origin. 2007 Feb 3
23 17433535 14-3-3 sigma increases the transcriptional activity of the androgen receptor in the absence of androgens. 2007 Aug 28 1
24 17679089 A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth. 2007 Aug 3 1
25 17728259 Androgen receptor regulation of the versican gene through an androgen response element in the proximal promoter. 2007 Nov 2 1
26 16598769 Androgen axis in prostate cancer. 2006 Oct 1 1
27 16166329 Decreased androgen receptor levels and receptor function in breast cancer contribute to the failure of response to medroxyprogesterone acetate. 2005 Sep 15 1
28 15176163 Antiandrogen oligonucleotides: active principles in hair- and skin-derived culture cells. 2004 May-Jun 3
29 12539229 R726L androgen receptor mutation is uncommon in prostate cancer families in the united states. 2003 Mar 1 1
30 12664061 Specific block of androgen receptor activity by antisense oligonucleotides. 2003 2
31 12799773 A role of aryl hydrocarbon receptor in the antiandrogenic effects of polycyclic aromatic hydrocarbons in LNCaP human prostate carcinoma cells. 2003 Jun 1
32 12891627 Gene expression changes following androgen receptor elimination in LNCaP prostate cancer cells. 2003 Aug 3
33 11857028 Inhibition of LNCaP prostate tumor growth in vivo by an antisense oligonucleotide directed against the human androgen receptor. 2002 Feb 1
34 12237244 Androgen receptors in prostate cancer. 2002 Sep 1
35 11606392 Overexpressed androgen receptor linked to p21WAF1 silencing may be responsible for androgen independence and resistance to apoptosis of a prostate cancer cell line. 2001 Oct 15 2
36 12083956 Androgen receptor mutations in carcinoma of the prostate: significance for endocrine therapy. 2001 1
37 10917202 Inhibition of LncaP prostate cancer cells by means of androgen receptor antisense oligonucleotides. 2000 Jul 1
38 11162897 Identification and characterization of two androgen response regions in the human neutral endopeptidase gene. 2000 Dec 22 2
39 10075669 Androgen-independent induction of prostate-specific antigen gene expression via cross-talk between the androgen receptor and protein kinase A signal transduction pathways. 1999 Mar 19 2
40 10477908 "Decoy" of androgen-responsive element induces apoptosis in LNCaP cells. 1999 Oct 1 1
41 9212051 Identification of a functional androgen-response element in the exon 1-coding sequence of the cystatin-related protein gene crp2. 1997 Jul 1
42 9233568 Further evidence for the importance of an androgen response element in the factor IX promoter. 1997 Jul 3
43 9001799 Rapid detection of a mutation hot-spot in the human androgen receptor. 1996 Oct 1
44 7748811 Androgens induce divergent proliferative responses in human breast cancer cell lines. 1995 May 2
45 7514587 Human androgen receptor binding to the androgen response element of prostate specific antigen. 1994 Jan-Feb 1
46 7968281 Detection of human androgen receptor mRNA in hepatocellular carcinoma by in situ hybridisation. 1994 Aug 1
47 8312279 Regulatory mechanism of human factor IX gene: protein binding at the Leyden-specific region. 1994 Feb 15 2
48 1424203 Point mutations detected in the androgen receptor gene of three men with partial androgen insensitivity syndrome. 1992 Sep 1
49 1491700 A consensus DNA-binding site for the androgen receptor. 1992 Dec 1
50 2293020 Definition of the human androgen receptor gene structure permits the identification of mutations that cause androgen resistance: premature termination of the receptor protein at amino acid residue 588 causes complete androgen resistance. 1990 Aug 1