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1 |
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27157787 | Bafetinib (INNO-406) reverses multidrug resistance by inhibiting the efflux function of ABCB1 and ABCG2 transporters. | 2016 May 9 |
1 |
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25823815 | Lyn modulates Claudin-2 expression and is a therapeutic target for breast cancer liver metastasis. | 2015 Apr 20 |
2 |
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23380277 | A neuropharmacokinetic assessment of bafetinib, a second generation dual BCR-Abl/Lyn tyrosine kinase inhibitor, in patients with recurrent high-grade gliomas. | 2013 May |
1 |
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23747655 | Bafetinib inhibits functional responses of human eosinophils in vitro. | 2013 Sep 5 |
2 |
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19890374 | A comprehensive target selectivity survey of the BCR-ABL kinase inhibitor INNO-406 by kinase profiling and chemical proteomics in chronic myeloid leukemia cells. | 2010 Jan |
1 |
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20310049 | Phase 1 study of INNO-406, a dual Abl/Lyn kinase inhibitor, in Philadelphia chromosome-positive leukemias after imatinib resistance or intolerance. | 2010 Jun 1 |
1 |
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21154127 | Bafetinib, a dual Bcr-Abl/Lyn tyrosine kinase inhibitor for the potential treatment of leukemia. | 2010 Dec |
2 |
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18191450 | Comparison of imatinib, dasatinib, nilotinib and INNO-406 in imatinib-resistant cell lines. | 2008 Jun |
1 |
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18338755 | Overcoming imatinib resistance using Src inhibitor CGP76030, Abl inhibitor nilotinib and Abl/Lyn inhibitor INNO-406 in newly established K562 variants with BCR-ABL gene amplification. | 2008 Jun 1 |
2 |
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19662183 | NS-187 (INNO-406), a Bcr-Abl/Lyn dual tyrosine kinase inhibitor. | 2007 Nov 14 |
2 |
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16546254 | In vivo antiproliferative effect of NS-187, a dual Bcr-Abl/Lyn tyrosine kinase inhibitor, on leukemic cells harbouring Abl kinase domain mutations. | 2006 Nov |
1 |
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16105974 | NS-187, a potent and selective dual Bcr-Abl/Lyn tyrosine kinase inhibitor, is a novel agent for imatinib-resistant leukemia. | 2005 Dec 1 |
3 |