| 1 |
34699250 | Tyrosine phosphorylation of NLRP3 by the Src family kinase Lyn suppresses the activity of the NLRP3 inflammasome. | 2021 Oct 26 |
1 |
| 2 |
31828293 | MiR-122-5p suppresses the proliferation, migration, and invasion of gastric cancer cells by targeting LYN. | 2020 Jan 2 |
1 |
| 3 |
32420483 | ACLY is the novel signaling target of PIP2/PIP3 and Lyn in acute myeloid leukemia. | 2020 May |
1 |
| 4 |
33328764 | Quantitative Tyrosine Phosphoproteomic Analysis of Resistance to Radiotherapy in Nasopharyngeal Carcinoma Cells. | 2020 |
1 |
| 5 |
30465710 | Synthetic biology of B cell activation: understanding signal amplification at the B cell antigen receptor using a rebuilding approach. | 2019 Mar 26 |
2 |
| 6 |
30540497 | Amelioration of amyloid β-FcγRIIb neurotoxicity and tau pathologies by targeting LYN. | 2019 Mar |
1 |
| 7 |
30923129 | A reevaluation of the spleen tyrosine kinase (SYK) activation mechanism. | 2019 May 10 |
1 |
| 8 |
31362927 | Interplay between HGAL and Grb2 proteins regulates B-cell receptor signaling. | 2019 Aug 13 |
1 |
| 9 |
31790499 | Expression of myeloid Src-family kinases is associated with poor prognosis in AML and influences Flt3-ITD kinase inhibitor acquired resistance. | 2019 |
1 |
| 10 |
29391601 | The oncogenic tyrosine kinase Lyn impairs the pro-apoptotic function of Bim. | 2018 Apr |
2 |
| 11 |
30038620 | Mast Cell Activation and Microtubule Organization Are Modulated by Miltefosine Through Protein Kinase C Inhibition. | 2018 |
1 |
| 12 |
28619847 | Targeted activation of the SHP-1/PP2A signaling axis elicits apoptosis of chronic lymphocytic leukemia cells. | 2017 Aug |
1 |
| 13 |
28811476 | Lyn and Fyn function as molecular switches that control immunoreceptors to direct homeostasis or inflammation. | 2017 Aug 15 |
1 |
| 14 |
27206658 | Differential Lyn-dependence of the SHIP1-deficient mast cell phenotype. | 2016 May 20 |
2 |
| 15 |
25587033 | Tyrosine phosphorylation of the Lyn Src homology 2 (SH2) domain modulates its binding affinity and specificity. | 2015 Mar |
1 |
| 16 |
24334106 | Activation of Src family tyrosine kinases by ferric ions. | 2014 Mar |
1 |
| 17 |
24352878 | Lyn-mediated procaspase 8 dimerization blocks apoptotic signaling in B-cell chronic lymphocytic leukemia. | 2014 Feb 6 |
1 |
| 18 |
24606526 | Leukaemic cells from chronic lymphocytic leukaemia patients undergo apoptosis following microtubule depolymerization and Lyn inhibition by nocodazole. | 2014 Jun |
1 |
| 19 |
24626044 | Abnormal red cell features associated with hereditary neurodegenerative disorders: the neuroacanthocytosis syndromes. | 2014 May |
1 |
| 20 |
23325840 | Targeting the LYN/HS1 signaling axis in chronic lymphocytic leukemia. | 2013 Mar 21 |
1 |
| 21 |
23509253 | FCRL5 exerts binary and compartment-specific influence on innate-like B-cell receptor signaling. | 2013 Apr 2 |
1 |
| 22 |
23583449 | A crucial role for Lyn in TIMP-1 erythroid cell survival signalling pathway. | 2013 May 21 |
4 |
| 23 |
23645696 | Phosphorylation of KRAB-associated protein 1 (KAP1) at Tyr-449, Tyr-458, and Tyr-517 by nuclear tyrosine kinases inhibits the association of KAP1 and heterochromatin protein 1α (HP1α) with heterochromatin. | 2013 Jun 14 |
2 |
| 24 |
23764002 | Epidermal growth factor receptor potentiates MCM7-mediated DNA replication through tyrosine phosphorylation of Lyn kinase in human cancers. | 2013 Jun 10 |
1 |
| 25 |
23949219 | MBNL142 and MBNL143 gene isoforms, overexpressed in DM1-patient muscle, encode for nuclear proteins interacting with Src family kinases. | 2013 Aug 15 |
1 |
| 26 |
22364282 | Targeting Lyn tyrosine kinase through protein fusions encompassing motifs of Cbp (Csk-binding protein) and the SOCS box of SOCS1. | 2012 Mar 15 |
2 |
| 27 |
22461510 | Phosphoproteomics identifies driver tyrosine kinases in sarcoma cell lines and tumors. | 2012 May 15 |
1 |
| 28 |
22581261 | DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation. | 2012 May 13 |
1 |
| 29 |
22845063 | The interaction between Lyn and FcεRIβ is indispensable for FcεRI-mediated human mast cell activation. | 2012 Oct |
1 |
| 30 |
23131831 | Novel Phosphorylations of IKKγ/NEMO. | 2012 Nov 6 |
1 |
| 31 |
21056031 | Apoptosis of hepatic stellate cells mediated by specific protein nitration. | 2011 Feb 1 |
1 |
| 32 |
21701493 | Lyn-mediated SHP-1 recruitment to CD5 contributes to resistance to apoptosis of B-cell chronic lymphocytic leukemia cells. | 2011 Nov |
1 |
| 33 |
21730355 | Quantitative phosphoproteomics revealed interplay between Syk and Lyn in the resistance to nilotinib in chronic myeloid leukemia cells. | 2011 Aug 25 |
3 |
| 34 |
21918188 | Myeloid differentiation factor-2 interacts with Lyn kinase and is tyrosine phosphorylated following lipopolysaccharide-induced activation of the TLR4 signaling pathway. | 2011 Oct 15 |
4 |
| 35 |
21951684 | Erythrocyte membrane changes of chorea-acanthocytosis are the result of altered Lyn kinase activity. | 2011 Nov 17 |
2 |
| 36 |
22566884 | Transmembrane adaptor proteins in the high-affinity IgE receptor signaling. | 2011 |
1 |
| 37 |
20205385 | Measurement of protein phosphorylation stoichiometry by selected reaction monitoring mass spectrometry. | 2010 May 7 |
3 |
| 38 |
20308635 | Functional analysis of Lyn kinase A and B isoforms reveals redundant and distinct roles in Fc epsilon RI-dependent mast cell activation. | 2010 May 1 |
2 |
| 39 |
20516366 | IVIg modulates BCR signaling through CD22 and promotes apoptosis in mature human B lymphocytes. | 2010 Sep 9 |
1 |
| 40 |
19124084 | Csk-binding protein can regulate Lyn signals controlling cell morphology. | 2009 Jun |
1 |
| 41 |
19175793 | The lectin Jacalin induces human B-lymphocyte apoptosis through glycosylation-dependent interaction with CD45. | 2009 Aug |
2 |
| 42 |
19206206 | Activation loop phosphorylation modulates Bruton's tyrosine kinase (Btk) kinase domain activity. | 2009 Mar 10 |
1 |
| 43 |
19832701 | Lyn-mediated mitochondrial tyrosine phosphorylation is required to preserve mitochondrial integrity in early liver regeneration. | 2009 Dec 23 |
2 |
| 44 |
17905674 | Src family kinases: regulation of their activities, levels and identification of new pathways. | 2008 Jan |
2 |
| 45 |
17993265 | Kit- and Fc epsilonRI-induced differential phosphorylation of the transmembrane adaptor molecule NTAL/LAB/LAT2 allows flexibility in its scaffolding function in mast cells. | 2008 Jan |
2 |
| 46 |
17998938 | Activation of Rac1 and the exchange factor Vav3 are involved in NPM-ALK signaling in anaplastic large cell lymphomas. | 2008 Apr 24 |
1 |
| 47 |
18070987 | Oncogenic association of the Cbp/PAG adaptor protein with the Lyn tyrosine kinase in human B-NHL rafts. | 2008 Feb 15 |
4 |
| 48 |
18086677 | Dynamic regulation of neutrophil survival through tyrosine phosphorylation or dephosphorylation of caspase-8. | 2008 Feb 29 |
2 |
| 49 |
18235045 | Lyn regulates BCR-ABL and Gab2 tyrosine phosphorylation and c-Cbl protein stability in imatinib-resistant chronic myelogenous leukemia cells. | 2008 Apr 1 |
2 |
| 50 |
18577747 | Association between imatinib-resistant BCR-ABL mutation-negative leukemia and persistent activation of LYN kinase. | 2008 Jul 2 |
2 |