Acetylcholine

choline O-acetyltransferase ; Homo sapiens







48 Article(s)
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1 35084573 Identification of cholinergic cells with chemosensory traits in the porcine uterus. 2022 Apr 4
2 33079431 In Situ Assembly of Choline Acetyltransferase Ligands by a Hydrothiolation Reaction Reveals Key Determinants for Inhibitor Design. 2021 Jan 11 2
3 33301603 Cortical VIP+ /ChAT+ interneurons: From genetics to function. 2021 Sep 2
4 33836585 Acetylcholine ameliorates colitis by promoting IL-10 secretion of monocytic myeloid-derived suppressor cells through the nAChR/ERK pathway. 2021 Mar 16 2
5 34360687 Interleukin-4 Promotes Tuft Cell Differentiation and Acetylcholine Production in Intestinal Organoids of Non-Human Primate. 2021 Jul 24 2
6 34512307 CSF and Plasma Cholinergic Markers in Patients With Cognitive Impairment. 2021 6
7 34637466 A novel in vitro assay model developed to measure both extracellular and intracellular acetylcholine levels for screening cholinergic agents. 2021 2
8 34743284 Immunohistochemical Expression of Choline Acetyltransferase and Catecholamine-Synthesizing Enzymes in Head-and-Neck and Thoracoabdominal Paragangliomas and Pheochromocytomas. 2021 Dec 1
9 32383816 Proton pump inhibitors act with unprecedented potencies as inhibitors of the acetylcholine biosynthesizing enzyme-A plausible missing link for their association with incidence of dementia. 2020 Jul 4
10 32486466 Human Neural Stem Cells Encoding ChAT Gene Restore Cognitive Function via Acetylcholine Synthesis, Aβ Elimination, and Neuroregeneration in APPswe/PS1dE9 Mice. 2020 May 31 2
11 32879219 Hippocampal Cholinergic Neurostimulating Peptide Suppresses LPS-Induced Expression of Inflammatory Enzymes in Human Macrophages. 2020 4
12 33298129 Effect of ciliary neurotrophic factor on neural differentiation of stem cells of human exfoliated deciduous teeth. 2020 Dec 9 1
13 33357230 Indirect cholinergic activation slows down pancreatic cancer growth and tumor-associated inflammation. 2020 Dec 24 2
14 30361890 Increased Active OMI/HTRA2 Serine Protease Displays a Positive Correlation with Cholinergic Alterations in the Alzheimer's Disease Brain. 2019 Jul 2
15 30585907 Eleutheroside E attenuates isoflurane-induced cognitive dysfunction by regulating the α7-nAChR-NMDAR pathway. 2019 Feb 6 1
16 29176551 Discovery of novel choline acetyltransferase inhibitors using structure-based virtual screening. 2017 Nov 24 1
17 26813123 Alzheimer's disease: Targeting the Cholinergic System. 2016 2
18 27087745 Human Neural Stem Cells Overexpressing Choline Acetyltransferase Restore Unconditioned Fear in Rats with Amygdala Injury. 2016 7
19 25676388 Changes in CSF cholinergic biomarkers in response to cell therapy with NGF in patients with Alzheimer's disease. 2015 Nov 2
20 26413144 Modeling the Interaction between β-Amyloid Aggregates and Choline Acetyltransferase Activity and Its Relation with Cholinergic Dysfunction through Two-Enzyme/Two-Compartment Model. 2015 9
21 23840379 Regulated Extracellular Choline Acetyltransferase Activity- The Plausible Missing Link of the Distant Action of Acetylcholine in the Cholinergic Anti-Inflammatory Pathway. 2013 6
22 21929870 Human neural stem cells overexpressing choline acetyltransferase restore cognitive function of kainic acid-induced learning and memory deficit animals. 2012 6
23 22245157 Human neural stem cells over-expressing choline acetyltransferase restore cognition in rat model of cognitive dysfunction. 2012 Apr 2
24 22607230 Chromatographic separation of reaction products from the choline acetyltransferase and carnitine acetyltransferase assay: differential ChAT and CrAT activity in brain extracts from Alzheimer's disease versus controls. 2012 Aug 4
25 22766481 Recent preclinical evidence advancing cell therapy for Alzheimer's disease. 2012 Sep 1
26 21115064 The cholinergic system, circadian rhythmicity, and time memory. 2011 Aug 10 2
27 21691765 Cholinergic imbalance in the multiple sclerosis hippocampus. 2011 Sep 2
28 19962381 Donepezil, an acetylcholinesterase inhibitor against Alzheimer's dementia, promotes angiogenesis in an ischemic hindlimb model. 2010 Apr 2
29 20560540 Redesign of cosubstrate specificity and identification of important residues for substrate binding to hChAT. 2010 Jul 27 1
30 19660442 Determination of high-affinity choline uptake (HACU) and choline acetyltransferase (ChAT) activity in the same population of cultured cells. 2009 Nov 10 3
31 18322398 Galanin hyperinnervation upregulates choline acetyltransferase expression in cholinergic basal forebrain neurons in Alzheimer's disease. 2008 1
32 16797789 82-kDa choline acetyltransferase is in nuclei of cholinergic neurons in human CNS and altered in aging and Alzheimer disease. 2007 Jul 2
33 17346753 Dysfunction of the non-neuronal cholinergic system in the airways and blood cells of patients with cystic fibrosis. 2007 May 30 1
34 12628456 The non-neuronal cholinergic system in humans: expression, function and pathophysiology. 2003 Mar 28 2
35 10885540 The cholinergic neuronal phenotype in Alzheimer's disease. 2000 Mar 4
36 10332935 Reappraising neurotransmitter-based strategies. 1999 Apr 2
37 10594838 Choline acetyltransferase: the structure, distribution and pathologic changes in the central nervous system. 1999 Nov 3
38 10344794 Production and functional expression of an epitope-tagged human choline acetyltransferase. 1998 Dec 2
39 9387876 Transcriptional activation of human choline acetyltransferase by AP2- and NGF-induced factors. 1997 Oct 3 1
40 8532116 Differential correlation between neurochemical deficits, neuropathology, and cognitive status in Alzheimer's disease. 1995 Sep-Oct 1
41 7682855 Identification and analysis of the human choline acetyltransferase gene promoter. 1993 Mar 1
42 3019230 Reduced phospholipase D activity in brain tissue samples from Alzheimer's disease patients. 1986 Aug 2
43 6133910 Muscarinic receptor compensation in hippocampus of Alzheimer patients. 1983 2
44 749543 [In vitro and in vivo effect of choline acetylase inhibitors on the acetylcholine levels of the central nervous system]. 1978 1
45 5968546 A radiochemical method for the estimation of choline acetyltransferase. 1966 Aug 1
46 18901877 Effect of convulsant and anticonvulsant agents on acetylcholine metabolism (activity of choline acetylase, cholinesterase) and on sensitivity to acetylcholine of effector organs. 1947 Dec 1 1
47 21024917 Studies on choline acetylase; the formation of acetylcholine in the nerve axon. 1946 May 1
48 21026216 On the formation of acetylcholine by choline acetylase in the nerve axon. 1946 1