Serine

Jun proto-oncogene, AP-1 transcription factor subunit ; Homo sapiens







102 Article(s)
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1 34893887 Structural basis of DNA methylation-dependent site selectivity of the Epstein-Barr virus lytic switch protein ZEBRA/Zta/BZLF1. 2022 Jan 11 1
2 34703881 lncRNA RP11-147L13.8 suppresses metastasis and chemo-resistance by modulating the phosphorylation of c-Jun protein in GBC. 2021 Dec 17 1
3 30948508 Dephosphorylation of the transcriptional cofactor NACA by the PP1A phosphatase enhances cJUN transcriptional activity and osteoblast differentiation. 2019 May 17 1
4 28127697 Differential Mechanisms of Inflammation and Endothelial Dysfunction by HIV-1 Subtype-B and Recombinant CRF02_AG Tat Proteins on Human Brain Microvascular Endothelial Cells: Implications for Viral Neuropathogenesis. 2018 Feb 1
5 29888211 c-Jun Proto-Oncoprotein Plays a Protective Role in Lung Epithelial Cells Exposed to Staphylococcal α-Toxin. 2018 1
6 28184937 Rhein exhibits antitumorigenic effects by interfering with the interaction between prolyl isomerase Pin1 and c-Jun. 2017 Mar 2
7 26755651 Cdk3-promoted epithelial-mesenchymal transition through activating AP-1 is involved in colorectal cancer metastasis. 2016 Feb 9 2
8 25530093 Identification of a c-Jun homolog from Litopenaeus vannamei as a downstream substrate of JNK in response to WSSV infection. 2015 Apr 1
9 26486083 Molecular mechanisms of cisplatin cytotoxicity in acute promyelocytic leukemia cells. 2015 Dec 1 1
10 24038215 Inhibition of apolipoprotein A-I expression by TNF-alpha in HepG2 cells: requirement for c-jun. 2014 Feb 1
11 25422452 Acquisition of an immunosuppressive protumorigenic macrophage phenotype depending on c-Jun phosphorylation. 2014 Dec 9 1
12 23404426 Inhibition of proliferation of estrogen receptor‑positive MCF‑7 human breast cancer cells by tamoxifen through c‑Jun transcription factors. 2013 Apr 3
13 23625009 Latency of Epstein-Barr virus is disrupted by gain-of-function mutant cellular AP-1 proteins that preferentially bind methylated DNA. 2013 May 14 1
14 22399296 p38γ mitogen-activated protein kinase (MAPK) confers breast cancer hormone sensitivity by switching estrogen receptor (ER) signaling from classical to nonclassical pathway via stimulating ER phosphorylation and c-Jun transcription. 2012 Apr 27 3
15 21296815 Hyperosmotic stress-induced corneal epithelial cell death through activation of Polo-like kinase 3 and c-Jun. 2011 May 16 1
16 21502402 Phosphorylation of serine 68 of Twist1 by MAPKs stabilizes Twist1 protein and promotes breast cancer cell invasiveness. 2011 Jun 1 1
17 21808000 Genetic framework for GATA factor function in vascular biology. 2011 Aug 16 2
18 19818398 Tyrosine 170 is dispensable for c-Jun turnover. 2010 Feb 1
19 19937805 Activation of c-Jun in the nuclei of neurons of the CA-1 in thrombin preconditioning occurs via PAR-1. 2010 May 1 1
20 20082306 Induced overexpression of protein kinase D1 stimulates mitogenic signaling in human pancreatic carcinoma PANC-1 cells. 2010 May 2
21 18814027 Endothelial cell-laminin interaction: modulation of LDH expression involves alpha6beta4 integrin-FAK-p38MAPK pathway. 2009 Aug 1
22 19176525 Phosphorylation of Activation Transcription Factor-2 at Serine 121 by Protein Kinase C Controls c-Jun-mediated Activation of Transcription. 2009 Mar 27 2
23 19435822 Activator protein-1 has an essential role in pancreatic cancer cells and is regulated by a novel Akt-mediated mechanism. 2009 May 4
24 19604147 Mammalian sterile 20-like kinase 3 (MST3) mediates oxidative-stress-induced cell death by modulating JNK activation. 2009 Sep 16 1
25 19890497 Pin1 as an anticancer drug target. 2009 Sep 1
26 17920329 Negative charged threonine 95 of c-Jun is essential for c-Jun N-terminal kinase-dependent phosphorylation of threonine 91/93 and stress-induced c-Jun biological activity. 2008 1
27 17952113 Calcineurin-mediated dephosphorylation of c-Jun Ser-243 is required for c-Jun protein stability and cell transformation. 2008 Apr 10 9
28 18419764 Pin1 promotes cell death in NGF-dependent neurons through a mechanism requiring c-Jun activity. 2008 Jul 1
29 18650425 Activation of Polo-like kinase 3 by hypoxic stresses. 2008 Sep 19 3
30 18713649 JNK regulates cell migration through promotion of tyrosine phosphorylation of paxillin. 2008 Nov 1
31 18822310 Arsenic trioxide phosphorylates c-Fos to transactivate p21(WAF1/CIP1) expression. 2008 Dec 1 1
32 16964287 Involvement of protein phosphatase 2A nuclear accumulation and subsequent inactivation of activator protein-1 in leptomycin B-inhibited cyclin D1 expression. 2007 Mar 8 5
33 16978906 Role of activator protein-1 on the effect of arginine-glycine-aspartic acid containing peptides on transforming growth factor-beta1 promoter activity. 2007 2
34 17215518 PP2B-mediated dephosphorylation of c-Jun C terminus regulates phorbol ester-induced c-Jun/Sp1 interaction in A431 cells. 2007 Mar 4
35 17325487 c-Jun expression and activation are restricted to CD30+ lymphoproliferative disorders. 2007 Mar 4
36 17510314 Src induces urokinase receptor gene expression and invasion/intravasation via activator protein-1/p-c-Jun in colorectal cancer. 2007 May 3
37 16481106 Activated c-Jun is present in neurofibrillary tangles in Alzheimer's disease brains. 2006 May 8 2
38 16733206 c-Jun activation is associated with proliferation and angiogenesis in invasive breast cancer. 2006 Jun 3
39 16023596 The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase. 2005 Jul 1
40 16123044 Regulation of the transcriptional activity of c-Fos by ERK. A novel role for the prolyl isomerase PIN1. 2005 Oct 21 1
41 16464740 Differential effects of tumor necrosis factor-alpha and CD40L on NF-kappa B inhibitory proteins I kappa B alpha, beta and epsilon and on the induction of the Jun amino-terminal kinase pathway in Ramos Burkitt lymphoma cells. 2005 Dec 1
42 14617628 JNK-dependent phosphorylation of c-Jun on serine 63 mediates nitric oxide-induced apoptosis of neuroblastoma cells. 2004 Feb 6 10
43 15135887 Activation of the c-Jun transcription factor following neurodegeneration in vivo. 2004 May 6 3
44 12644711 The LIM-only protein FHL2 is a serum-inducible transcriptional coactivator of AP-1. 2003 Apr 1 2
45 12809553 Phosphorylation of BATF regulates DNA binding: a novel mechanism for AP-1 (activator protein-1) regulation. 2003 Sep 1 1
46 12917327 Lithium blocks the c-Jun stress response and protects neurons via its action on glycogen synthase kinase 3. 2003 Sep 2
47 12947046 An activator protein 1-like motif mediates 17beta-estradiol repression of gonadotropin-releasing hormone receptor promoter via an estrogen receptor alpha-dependent mechanism in ovarian and breast cancer cells. 2003 Dec 1
48 14657232 GDNF-deprived sympathetic neurons die via a novel nonmitochondrial pathway. 2003 Dec 8 1
49 11739718 c-Jun and hypoxia-inducible factor 1 functionally cooperate in hypoxia-induced gene transcription. 2002 Jan 2
50 11801649 Synergy of IL-12 and IL-18 for IFN-gamma gene expression: IL-12-induced STAT4 contributes to IFN-gamma promoter activation by up-regulating the binding activity of IL-18-induced activator protein 1. 2002 Feb 1 2