Acetylcysteine

Jun proto-oncogene, AP-1 transcription factor subunit ; Homo sapiens







28 Article(s)
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1 34776955 ROS/JNK/C-Jun Pathway is Involved in Chaetocin Induced Colorectal Cancer Cells Apoptosis and Macrophage Phagocytosis Enhancement. 2021 2
2 32635894 The natural alkaloid Jerantinine B has activity in acute myeloid leukemia cells through a mechanism involving c-Jun. 2020 Jul 7 1
3 30584464 High Glucose-Induced ROS Production Stimulates Proliferation of Pancreatic Cancer via Inactivating the JNK Pathway. 2018 2
4 24651440 Longikaurin A, a natural ent-kaurane, induces G2/M phase arrest via downregulation of Skp2 and apoptosis induction through ROS/JNK/c-Jun pathway in hepatocellular carcinoma cells. 2014 Mar 20 1
5 24938881 Protective effects of certain pharmaceutical compounds against abrin induced cell death in Jurkat cell line. 2014 Aug 1
6 24025361 A novel synthetic derivative of the natural product berbamine inhibits cell viability and induces apoptosis of human osteosarcoma cells, associated with activation of JNK/AP-1 signaling. 2013 Nov 2
7 21806545 Mechanism of the inhibitory effect of atorvastatin on leptin expression induced by angiotensin II in cultured human coronary artery smooth muscle cells. 2012 Jan 1
8 21254278 N-acetyl-L-cysteine counteracts oxidative stress and prevents H2O2 induced germ cell apoptosis through down-regulation of caspase-9 and JNK/c-Jun. 2011 Feb 1
9 21268080 Cigarette smoke extract regulates cytosolic phospholipase A2 expression via NADPH oxidase/MAPKs/AP-1 and p300 in human tracheal smooth muscle cells. 2011 Feb 1
10 21640077 Role of Pin1 in UVA-induced cell proliferation and malignant transformation in epidermal cells. 2011 Jun 24 2
11 20632440 8-Bromo-7-methoxychrysin-induced apoptosis of hepatocellular carcinoma cells involves ROS and JNK. 2010 Jul 21 1
12 21172010 c-Jun NH2-terminal kinase-dependent upregulation of DR5 mediates cooperative induction of apoptosis by perifosine and TRAIL. 2010 Dec 20 1
13 18032928 Reactive oxygen species contribute to cell killing and P-glycoprotein downregulation by salvicine in multidrug resistant K562/A02 cells. 2007 Nov 1
14 16298762 alpha-Lipoic acid and N-acetyl cysteine prevent zinc deficiency-induced activation of NF-kappaB and AP-1 transcription factors in human neuroblastoma IMR-32 cells. 2006 Jan 1
15 15670787 Identification of ASK1, MKK4, JNK, c-Jun, and caspase-3 as a signaling cascade involved in cadmium-induced neuronal cell apoptosis. 2005 Mar 4 1
16 15989974 The role of c-Jun in the AP-1 activation induced by naturally occurring isothiocyanates. 2005 Sep 1
17 15033544 Acute cadmium exposure enhances AP-1 DNA binding and induces cytokines expression and heat shock protein 70 in HepG2 cells. 2004 May 3 1
18 15208668 Interleukin-1beta stimulates IL-8 expression through MAP kinase and ROS signaling in human gastric carcinoma cells. 2004 Aug 26 1
19 15289320 Inhibition of activator protein 1 activation, vascular endothelial growth factor, and cyclooxygenase-2 expression by 15-deoxy-Delta12,14-prostaglandin J2 in colon carcinoma cells: evidence for a redox-sensitive peroxisome proliferator-activated receptor-gamma-independent mechanism. 2004 Aug 1 1
20 12713590 Topical N-acetyl cysteine and genistein prevent ultraviolet-light-induced signaling that leads to photoaging in human skin in vivo. 2003 May 2
21 10964049 Induction of the c-jun protooncogene expression by areca nut extract and arecoline on oral mucosal fibroblasts. 2000 Sep 1
22 10026227 JunB forms the majority of the AP-1 complex and is a target for redox regulation by receptor tyrosine kinase and G protein-coupled receptor agonists in smooth muscle cells. 1999 Feb 26 1
23 9043100 Suppression of UVB-induced c-fos and c-jun expression in human keratinocytes by N-acetylcysteine. 1997 Jan 3
24 8853906 Transforming growth factor beta 1-induced apoptosis in human ovarian carcinoma cells: protection by the antioxidant N-acetylcysteine and bcl-2. 1996 Aug 1
25 7673190 Reactive oxygen intermediates mediate angiotensin II-induced c-Jun.c-Fos heterodimer DNA binding activity and proliferative hypertrophic responses in myogenic cells. 1995 Sep 22 1
26 7724734 Heterogeneity in c-jun gene expression in normal and malignant cells exposed to either ionizing radiation or hydrogen peroxide. 1995 May 2
27 7835407 The redox active components H2O2 and N-acetyl-L-cysteine regulate expression of c-jun and c-fos in lens systems. 1994 Aug 3
28 8035787 Regulation of c-jun expression during hypoxic and low-glucose stress. 1994 Aug 3