AZD 6244

eukaryotic translation initiation factor 2 alpha kinase 3 ; Homo sapiens







8 Article(s)
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PMID
Title
Pub. Year
#Total Relationships
1 32975370 Functional imaging of RAS pathway targeting in malignant peripheral nerve sheath tumor cells and xenografts. 2020 Dec 1
2 28866094 Palbociclib, a selective CDK4/6 inhibitor, enhances the effect of selumetinib in RAS-driven non-small cell lung cancer. 2017 Nov 1 1
3 25342139 BYL719, a selective inhibitor of phosphoinositide 3-Kinase α, enhances the effect of selumetinib (AZD6244, ARRY-142886) in KRAS-mutant non-small cell lung cancer. 2015 Feb 1
4 26137449 Inhibitors of pan-PI3K Signaling Synergize with BRAF or MEK Inhibitors to Prevent BRAF-Mutant Melanoma Cell Growth. 2015 1
5 26567773 Targeting inhibition of extracellular signal-regulated kinase kinase pathway with AZD6244 (ARRY-142886) suppresses growth and angiogenesis of gastric cancer. 2015 Nov 16 2
6 24567366 DOC-MEK: a double-blind randomized phase II trial of docetaxel with or without selumetinib in wild-type BRAF advanced melanoma. 2014 May 1
7 21286012 Could HBx protein expression affect signal pathway inhibition by gefitinib or selumetinib, a MEK inhibitor, in hepatocellular carcinoma cell lines? 2011 Feb 2
8 21124782 Combination treatment with MEK and AKT inhibitors is more effective than each drug alone in human non-small cell lung cancer in vitro and in vivo. 2010 Nov 29 1