Cysteine

prolyl 4-hydroxylase subunit beta ; Homo sapiens







80 Article(s)
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Pub. Year
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1 35077997 The extracellular Ero1α/PDI electron transport system regulates platelet function by increasing glutathione reduction potential. 2022 Apr 9
2 35385753 Protein disulfide isomerase modulation of TRPV1 controls heat hyperalgesia in chronic pain. 2022 Apr 5 2
3 33675119 Hydrogen sulphide reduces hyperhomocysteinaemia-induced endothelial ER stress by sulfhydrating protein disulphide isomerase to attenuate atherosclerosis. 2021 Apr 2
4 34071205 Therapeutic Targeting of Protein Disulfide Isomerase PDIA1 in Multiple Myeloma. 2021 May 28 1
5 31734460 Urate hydroperoxide oxidizes endothelial cell surface protein disulfide isomerase-A1 and impairs adherence. 2020 Mar 1
6 32087196 Phase Separation and Cytotoxicity of Tau are Modulated by Protein Disulfide Isomerase and S-nitrosylation of this Molecular Chaperone. 2020 Mar 27 1
7 32201313 Role of the ERO1-PDI interaction in oxidative protein folding and disease. 2020 Jun 1
8 32352225 A molecular dynamics approach on the Y393C variant of protein disulfide isomerase A1. 2020 Dec 1
9 32719007 Characterization of the endoplasmic reticulum-resident peroxidases GPx7 and GPx8 shows the higher oxidative activity of GPx7 and its linkage to oxidative protein folding. 2020 Sep 4 2
10 32768572 Cysteine 343 in the substrate binding domain is the primary S-Nitrosylated site in protein disulfide isomerase. 2020 Nov 20 1
11 30580571 Redox Activation of Nox1 (NADPH Oxidase 1) Involves an Intermolecular Disulfide Bond Between Protein Disulfide Isomerase and p47phox in Vascular Smooth Muscle Cells. 2019 Feb 6
12 28619231 Endoplasmic reticulum chaperones tweak the mitochondrial calcium rheostat to control metabolism and cell death. 2018 Mar 2
13 29191937 Peroxynitrite preferentially oxidizes the dithiol redox motifs of protein-disulfide isomerase. 2018 Jan 26 3
14 30671024 Protein Disulfide Isomerase Modulates the Activation of Thyroid Hormone Receptors. 2018 2
15 28122739 The integrin PSI domain has an endogenous thiol isomerase function and is a novel target for antiplatelet therapy. 2017 Mar 30 1
16 28215702 Nitroarachidonic acid (NO2AA) inhibits protein disulfide isomerase (PDI) through reversible covalent adduct formation with critical cysteines. 2017 May 10
17 28648146 Emerging roles of protein disulfide isomerase in cancer. 2017 Aug 2
18 28867746 Modulation of Unfolded Protein Response by Methylmercury. 2017 2
19 26840563 Oxidation of heat shock protein 60 and protein disulfide isomerase activates ERK and migration of human hepatocellular carcinoma HepG2. 2016 Mar 8 1
20 27703014 Human ER Oxidoreductin-1α (Ero1α) Undergoes Dual Regulation through Complementary Redox Interactions with Protein-Disulfide Isomerase. 2016 Nov 11 1
21 28053690 Potential Role of Protein Disulfide Isomerase in Metabolic Syndrome-Derived Platelet Hyperactivity. 2016 1
22 25697776 A PDI-catalyzed thiol-disulfide switch regulates the production of hydrogen peroxide by human Ero1. 2015 Jun 2
23 25697777 Structures and functions of protein disulfide isomerase family members involved in proteostasis in the endoplasmic reticulum. 2015 Jun 2
24 25724691 Understanding mammalian glutathione peroxidase 7 in the light of its homologs. 2015 Jun 1
25 26385697 The neuroprotective role of ferrostatin-1 under rotenone-induced oxidative stress in dopaminergic neuroblastoma cells. 2015 Oct 1
26 24415753 Protein disulfide isomerase directly interacts with β-actin Cys374 and regulates cytoskeleton reorganization. 2014 Feb 28 1
27 22920903 S-nitrosation/denitrosation in cardiovascular pathologies: facts and concepts for the rational design of S-nitrosothiols. 2013 2
28 23192347 The crystal structure of the protein-disulfide isomerase family member ERp27 provides insights into its substrate binding capabilities. 2013 Jan 18 3
29 23454490 Protein disulfide isomerase and glutathione are alternative substrates in the one Cys catalytic cycle of glutathione peroxidase 7. 2013 Jun 2
30 24024174 Protein disulfide isomerase may facilitate the efflux of nitrite derived S-nitrosothiols from red blood cells. 2013 1
31 24043701 Ero1-α and PDIs constitute a hierarchical electron transfer network of endoplasmic reticulum oxidoreductases. 2013 Sep 16 2
32 22572242 Arabidopsis cotyledon chloroplast biogenesis factor CYO1 uses glutathione as an electron donor and interacts with PSI (A1 and A2) and PSII (CP43 and CP47) subunits. 2012 Aug 15 4
33 22988091 Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment. 2012 Oct 2 2
34 21424268 Protein disulphide isomerase-assisted functionalization of keratin-based matrices. 2011 May 3
35 21481187 Bacitracin inhibits the reductive activity of protein disulfide isomerase by disulfide bond formation with free cysteines in the substrate-binding domain. 2011 Jun 2
36 21875564 Chemical stress on protein disulfide isomerases and inhibition of their functions. 2011 1
37 22715587 The potential of protein disulfide isomerase as a therapeutic drug target. 2011 1
38 20026073 Modulation of an active-site cysteine pKa allows PDI to act as a catalyst of both disulfide bond formation and isomerization. 2010 Mar 5 5
39 20097158 Rescue of ER oxidoreductase function through polyphenolic phytochemical intervention: implications for subcellular traffic and neurodegenerative disorders. 2010 Feb 19 1
40 20423326 Human pancreas-specific protein disulfide-isomerase (PDIp) can function as a chaperone independently of its enzymatic activity by forming stable complexes with denatured substrate proteins. 2010 Jul 1 1
41 19361226 Solution structure and dynamics of ERp18, a small endoplasmic reticulum resident oxidoreductase . 2009 Jun 2 4
42 19402212 Protein disulfide isomerase overexpression in vascular smooth muscle cells induces spontaneous preemptive NADPH oxidase activation and Nox1 mRNA expression: effects of nitrosothiol exposure. 2009 Apr 15 1
43 19773442 Nitrosative stress-induced s-glutathionylation of protein disulfide isomerase leads to activation of the unfolded protein response. 2009 Oct 1 1
44 17939758 In vivo reduction-oxidation state of protein disulfide isomerase: the two active sites independently occur in the reduced and oxidized forms. 2008 Jan 3
45 18833192 A novel disulphide switch mechanism in Ero1alpha balances ER oxidation in human cells. 2008 Nov 19 2
46 17074504 Identification of redox sensitive thiols of protein disulfide isomerase using isotope coded affinity technology and mass spectrometry. 2007 Feb 5
47 16677073 Dynamic retention of Ero1alpha and Ero1beta in the endoplasmic reticulum by interactions with PDI and ERp44. 2006 Mar-Apr 1
48 16677078 ERp29, an unusual redox-inactive member of the thioredoxin family. 2006 Mar-Apr 1
49 16142915 Catalysis of protein disulfide bond isomerization in a homogeneous substrate. 2005 Sep 13 3
50 14659757 A conserved arginine plays a role in the catalytic cycle of the protein disulphide isomerases. 2004 Jan 2 1