Zidovudine

UDP glucuronosyltransferase family 1 member A complex locus ; Homo sapiens







13 Article(s)
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1 34575401 PBPK Modeling as a Tool for Predicting and Understanding Intestinal Metabolism of Uridine 5'-Diphospho-glucuronosyltransferase Substrates. 2021 Aug 24 2
2 34684027 A Novel Method for Predicting the Human Inherent Clearance and Its Application in the Study of the Pharmacokinetics and Drug-Drug Interaction between Azidothymidine and Fluconazole Mediated by UGT Enzyme. 2021 Oct 19 5
3 32651149 Regional distributions of UDP-glucuronosyltransferase activities toward estradiol and serotonin in the liver and small intestine of cynomolgus macaques. 2020 Aug 1
4 30036684 Design and optimization of the cocktail assay for rapid assessment of the activity of UGT enzymes in human and rat liver microsomes. 2018 Oct 1 1
5 22543504 Gossypol exhibits a strong influence towards UDP-glucuronosyltransferase (UGT) 1A1, 1A9 and 2B7-mediated metabolism of xenobiotics and endogenous substances. 2012 Apr 27 1
6 21098645 Effects of cell differentiation and assay conditions on the UDP-glucuronosyltransferase activity in Caco-2 cells. 2011 Mar 1
7 19475557 Interactions between human UDP-glucuronosyltransferase (UGT) 2B7 and UGT1A enzymes. 2010 Jan 1
8 18832476 Prediction of drug clearance by glucuronidation from in vitro data: use of combined cytochrome P450 and UDP-glucuronosyltransferase cofactors in alamethicin-activated human liver microsomes. 2009 Jan 1
9 16542204 Quantitative prediction of in vivo inhibitory interactions involving glucuronidated drugs from in vitro data: the effect of fluconazole on zidovudine glucuronidation. 2006 Apr 2
10 16139098 Assessment of UDP-glucuronosyltransferase catalyzed formation of ethyl glucuronide in human liver microsomes and recombinant UGTs. 2005 Oct 29 1
11 15258106 Human placental glucuronidation and transport of 3'azido-3'-deoxythymidine and uridine diphosphate glucuronic acid. 2004 Aug 5
12 10772627 3'-azido-3'-deoxythimidine (AZT) is glucuronidated by human UDP-glucuronosyltransferase 2B7 (UGT2B7). 2000 May 5
13 9660989 Glucuronidation of 3'-azido-3'-deoxythymidine (zidovudine) by human liver microsomes: relevance to clinical pharmacokinetic interactions with atovaquone, fluconazole, methadone, and valproic acid. 1998 Jul 3