| 1 |
34199777 | Endothelin-1 as a Mediator of Heme Oxygenase-1-Induced Stemness in Colorectal Cancer: Influence of p53. | 2021 Jun 4 |
1 |
| 2 |
32423820 | Blockade of endothelin receptor A enhances the therapeutic efficacy of gemcitabine in pancreatic cancer cells. | 2020 Jun 25 |
1 |
| 3 |
31237545 | Bosentan Therapy in a Patient with Failed Fontan Procedure: A Case Report. | 2019 May 8 |
1 |
| 4 |
28735030 | Effect of bosentan therapy in persistent pulmonary hypertension of the newborn. | 2018 Feb |
1 |
| 5 |
29099661 | First-in-child use of the oral soluble guanylate cyclase stimulator riociguat in pulmonary arterial hypertension. | 2018 Jan-Mar |
1 |
| 6 |
28300593 | Functional estimation of endothelin-1 receptor antagonism by bosentan, macitentan and ambrisentan in human pulmonary and radial arteries in vitro. | 2017 Jun 5 |
1 |
| 7 |
28401480 | Target-Mediated Drug Disposition Pharmacokinetic-Pharmacodynamic Model of Bosentan and Endothelin-1. | 2017 Dec |
1 |
| 8 |
28640077 | Improvement of peripheral artery disease with Sildenafil and Bosentan combined therapy in a patient with limited cutaneous systemic sclerosis: A case report. | 2017 Jun |
1 |
| 9 |
27045668 | Clinical drug-drug interactions of bosentan, a potent endothelial receptor antagonist, with various drugs: Physiological role of enzymes and transporters. | 2016 Jul |
1 |
| 10 |
27129065 | Raynaud's phenomenon and digital ischaemia--pharmacologic approach and alternative treatment options. | 2016 |
1 |
| 11 |
27313275 | Glycosylation of α2δ1 subunit: a sweet talk with Cav1.2 channels. | 2016 Jul |
1 |
| 12 |
27534881 | Endothelin research and the discovery of macitentan for the treatment of pulmonary arterial hypertension. | 2016 Oct 1 |
1 |
| 13 |
25535031 | Desmethyl bosentan displays a similar in vitro interaction profile as bosentan. | 2015 Feb |
1 |
| 14 |
26526351 | Endothelin receptor-antagonists suppress lipopolysaccharide-induced cytokine release from alveolar macrophages of non-smokers, smokers and COPD subjects. | 2015 Dec 5 |
1 |
| 15 |
24851934 | Macitentan (Opsumit) for the treatment of pulmonary arterial hypertension. | 2014 Jul |
1 |
| 16 |
24937643 | Bosentan in pulmonary hypertension associated with fibrotic idiopathic interstitial pneumonia. | 2014 Jul 15 |
1 |
| 17 |
21763017 | Treatment of segmental pulmonary artery hypertension in adults with congenital heart disease. | 2013 Mar 20 |
1 |
| 18 |
23200808 | Bosentan inhibits oxidative and nitrosative stress and rescues occlusive pulmonary hypertension. | 2013 Mar |
1 |
| 19 |
23219525 | Influence of sildenafil and tadalafil on the enzyme- and transporter-inducing effects of bosentan and ambrisentan in LS180 cells. | 2013 Jan 15 |
1 |
| 20 |
23292819 | Management of Raynaud's phenomenon and digital ischemia. | 2013 Jan |
1 |
| 21 |
23363065 | The effect of the endothelin-1 receptor antagonist, bosentan, on patients with poorly controlled asthma: a 17-week, double-blind, placebo-controlled crossover pilot study. | 2013 May |
1 |
| 22 |
23590298 | Inflammatory responses of airway smooth muscle cells and effects of endothelin receptor antagonism. | 2013 Jul |
1 |
| 23 |
21432755 | Bosentan effects on hemodynamics and clinical outcome in heart failure patients with pulmonary hypertension awaiting cardiac transplantation. | 2012 Feb |
1 |
| 24 |
21828025 | Bosentan inhibits cigarette smoke-induced endothelin receptor expression in pulmonary arteries. | 2012 Apr |
1 |
| 25 |
22359440 | Homology modeling, active site prediction, and targeting the anti hypertension activity through molecular docking on endothelin - B receptor domain. | 2012 |
1 |
| 26 |
22480514 | Comparison of human ETA and ETB receptor signalling via G-protein and β-arrestin pathways. | 2012 Oct 15 |
3 |
| 27 |
22483689 | Endothelin-1 enhances β₂-adrenoceptor gene transcription in human lung fibroblasts. | 2012 Oct 15 |
1 |
| 28 |
22561246 | Purification and characterization of recombinant human endothelin receptor type A. | 2012 Jul |
2 |
| 29 |
21132305 | Successful bosentan therapy for pulmonary arterial hypertension associated with hereditary hemorrhagic telangiectasia. | 2011 Mar |
1 |
| 30 |
21283970 | Systemic sclerosis - a systematic overview: part 2 - immunosuppression, treatment of SSc-associated vasculopathy, and treatment of pulmonary arterial hypertension. | 2011 Jan |
1 |
| 31 |
21501604 | Differential modulation of the expression of important drug metabolising enzymes and transporters by endothelin-1 receptor antagonists ambrisentan and bosentan in vitro. | 2011 Jun 25 |
2 |
| 32 |
21527360 | Rationale and design of a trial on the role of bosentan in Fontan patients: improvement of exercise capacity? | 2011 Jul |
2 |
| 33 |
21839301 | Combination therapy with an endothelin-1 receptor antagonist (bosentan) and a phosphodiesterase V inhibitor (sildenafil) for the management of severe digital ulcerations in systemic sclerosis. | 2011 Sep |
1 |
| 34 |
19171388 | Combination of sitaxentan and tadalafil for idiopathic pulmonary arterial hypertension following relapse on bosentan. | 2010 Oct 29 |
1 |
| 35 |
20965396 | Pulmonary arterial hypertension in women. | 2010 Oct |
1 |
| 36 |
21081213 | The cardiovascular physiology and pharmacology of endothelin-1. | 2010 |
1 |
| 37 |
21244767 | Bosentan treatment for Raynauds phenomenon and skin fibrosis in patients with Systemic Sclerosis and pulmonary arterial hypertension: an open-label, observational, retrospective study. | 2010 Oct-Dec |
1 |
| 38 |
19081217 | [Pulmonary arterial hypertension related to systemic sclerosis in 2008]. | 2009 Feb |
1 |
| 39 |
19302565 | Low-dose combination therapy of severe digital ulcers in diffuse progressive systemic sclerosis with the endothelin-1 receptor antagonist bosentan and the phosphodiesterase V inhibitor sildenafil. | 2009 Oct |
1 |
| 40 |
19335744 | A review of STRIDE-2 and STRIDE-2X: the case for selective endothelin receptor blockade. | 2009 Jun |
1 |
| 41 |
19417139 | Epithelial-to-mesenchymal transition and resistance to ingenol 3-angelate, a novel protein kinase C modulator, in colon cancer cells. | 2009 May 15 |
1 |
| 42 |
19523174 | Successful treatment of persistent pulmonary hypertension of the newborn with bosentan. | 2009 Oct |
1 |
| 43 |
19688101 | Bosentan in the treatment of pulmonary arterial hypertension with the focus on the mildly symptomatic patient. | 2009 |
1 |
| 44 |
19850966 | TNFalpha-induced GM-CSF release from human airway smooth muscle cells depends on activation of an ET-1 autoregulatory positive feedback mechanism. | 2009 Dec |
1 |
| 45 |
18390125 | Role of iloprost and bosentan in pulmonary arterial hypertension. | 2008 Jan-Mar |
1 |
| 46 |
18515326 | Endothelins modulate inflammatory reaction in zymosan-induced arthritis: participation of LTB4, TNF-alpha, and CXCL-1. | 2008 Sep |
2 |
| 47 |
18536629 | [Pulmonary arterial hypertension in women]. | 2008 Apr |
1 |
| 48 |
17234519 | Sitaxsentan treatment for patients with pulmonary arterial hypertension discontinuing bosentan. | 2007 Jan |
1 |
| 49 |
17439935 | Bosentan use in systemic lupus erythematosus patients with pulmonary arterial hypertension. | 2007 |
1 |
| 50 |
17603693 | [Treatment of digital ulcers in systemtic sclerosis with endothelin-1 receptor antagonist (bosentan)]. | 2007 Apr-Jun |
1 |