Glucuronides

ATP binding cassette subfamily C member 2 ; Rattus norvegicus







30 Article(s)
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1 30248416 Emodin-induced hepatotoxicity was exacerbated by probenecid through inhibiting UGTs and MRP2. 2018 Nov 15 2
2 27555820 Inhibition of P-Glycoprotein and Multidrug Resistance-Associated Protein 2 Regulates the Hepatobiliary Excretion and Plasma Exposure of Thienorphine and Its Glucuronide Conjugate. 2016 1
3 22407408 Association of multidrug resistance-associated protein 2 single nucleotide polymorphism rs12762549 with the basal plasma levels of phase II metabolites of isoflavonoids in healthy Japanese individuals. 2012 May 1
4 23027342 CM2 antigen, a potential novel molecule participating in glucuronide transport on rat hepatocyte canalicular membrane. 2012 Jun 29 2
5 20089784 Multidrug resistance proteins restrain the intestinal absorption of trans-resveratrol in rats. 2010 Mar 1
6 19156843 Hepatic metabolism and biliary excretion of valerenic acid in isolated perfused rat livers: role of Mrp2 (Abcc2). 2009 Oct 2
7 19214140 Multidrug resistance-related protein 2 genotype of the donor affects kidney graft function. 2009 Apr 1
8 19703370 Altered expression of MRP2, MRP3 and UGT2B1 in the liver affects the disposition of morphine and its glucuronide conjugate in a rat model of cholestasis. 2009 Sep 1
9 19736994 Disposition of naringenin via glucuronidation pathway is affected by compensating efflux transporters of hydrophilic glucuronides. 2009 Nov-Dec 1
10 17724663 Metabolism and disposition of resveratrol in the isolated perfused rat liver: role of Mrp2 in the biliary excretion of glucuronides. 2008 Apr 2
11 18625249 Differential metabolism of 4-n- and 4-tert-octylphenols in perfused rat liver. 2008 Aug 1 2
12 16272406 Role of Mrp2 in the hepatic disposition of mycophenolic acid and its glucuronide metabolites: effect of cyclosporine. 2006 Feb 1
13 16772539 Disposition and sterol-lowering effect of ezetimibe in multidrug resistance-associated protein 2-deficient rats. 2006 Sep 2
14 16899240 Function of multidrug resistance-associated protein 2 in acute hepatic failure rats. 2006 Sep 28 1
15 16959944 The important role of Bcrp (Abcg2) in the biliary excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in mice. 2006 Dec 1
16 17009103 4-Hydroxyacetophenone-induced choleresis in rats is mediated by the Mrp2-dependent biliary secretion of its glucuronide conjugate. 2006 Nov 1
17 15466492 Bisphenol a glucuronidation and excretion in liver of pregnant and nonpregnant female rats. 2005 Jan 1
18 15069549 Metabolism of UCN-01 in isolated perfused rat liver: role of Mrp2 in the biliary excretion of glucuronides. 2004 May 3
19 11306690 Charged amino acids in the transmembrane domains are involved in the determination of the substrate specificity of rat Mrp2. 2001 May 3
20 10976015 The pathophysiology of cholestasis with special reference to primary biliary cirrhosis. 2000 Aug 1
21 10997931 Both cMOAT/MRP2 and another unknown transporter(s) are responsible for the biliary excretion of glucuronide conjugate of the nonpeptide angiotensin II antagonist, telmisaltan. 2000 Oct 6
22 19003398 Basolateral and canalicular transport of xenobiotics in the hepatocyte: A review. 2000 Nov 2
23 10024515 Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione. 1999 Mar 1 2
24 10590710 [Analysis of xenobiotic detoxification system mediated by efflux transporters]. 1999 Nov 2
25 9425227 Mutations in the canilicular multispecific organic anion transporter (cMOAT) gene, a novel ABC transporter, in patients with hyperbilirubinemia II/Dubin-Johnson syndrome. 1998 Feb 1
26 9495864 Carrier-mediated mechanism for the biliary excretion of the quinolone antibiotic grepafloxacin and its glucuronide in rats. 1998 Mar 4
27 9875554 Excretion of GSSG and glutathione conjugates mediated by MRP1 and cMOAT/MRP2. 1998 1
28 9157988 Multiplicity of biliary excretion mechanisms for irinotecan, CPT-11, and its metabolites in rats. 1997 May 15 2
29 9262353 Kinetic analysis of the primary active transport of conjugated metabolites across the bile canalicular membrane: comparative study of S-(2,4-dinitrophenyl)-glutathione and 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)benzothiazole glucuronide. 1997 Aug 1
30 9397986 Modulation of liver canalicular transport processes by the tyrosine-kinase inhibitor genistein: implications of genistein metabolism in the rat. 1997 Dec 2