| 1 |
34772733 | EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma. | 2022 Mar 1 |
1 |
| 2 |
35119862 | Dynamics of the Histone Acetyltransferase Lysine-Rich Loop in the Catalytic Core of the CREB-Binding Protein. | 2022 Feb 28 |
2 |
| 3 |
35512565 | Structure-activity relationship and antitumor activity of 1,4-pyrazine-containing inhibitors of histone acetyltransferases P300/CBP. | 2022 Jul 5 |
1 |
| 4 |
32737855 | CBP-mediated Slug acetylation stabilizes Slug and promotes EMT and migration of breast cancer cells. | 2021 Apr |
2 |
| 5 |
33400925 | Targeted degradation of the enhancer lysine acetyltransferases CBP and p300. | 2021 Apr 15 |
4 |
| 6 |
33938178 | Lysine acetyltransferase Tip60 acetylates the APP adaptor Fe65 to increase its transcriptional activity. | 2021 Mar 26 |
1 |
| 7 |
34071322 | Histone Deacetylase Inhibitors Ameliorate Morphological Defects and Hypoexcitability of iPSC-Neurons from Rubinstein-Taybi Patients. | 2021 May 28 |
2 |
| 8 |
34201346 | CBP/p300: Critical Co-Activators for Nuclear Steroid Hormone Receptors and Emerging Therapeutic Targets in Prostate and Breast Cancers. | 2021 Jun 8 |
2 |
| 9 |
34251718 | Leukemogenesis via aberrant self-renewal by the MLL/AEP-mediated transcriptional activation system. | 2021 Oct |
1 |
| 10 |
34255515 | Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain. | 2021 Jul 22 |
4 |
| 11 |
34331108 | Repurposing proscillaridin A in combination with decitabine against embryonal rhabdomyosarcoma RD cells. | 2021 Nov |
1 |
| 12 |
34353856 | miR-766-5p Targets Super-Enhancers by Downregulating CBP and BRD4. | 2021 Oct 15 |
1 |
| 13 |
34564982 | FTO-stabilized lncRNA HOXC13-AS epigenetically upregulated FZD6 and activated Wnt/β-catenin signaling to drive cervical cancer proliferation, invasion, and EMT. | 2021 Jul-Aug |
2 |
| 14 |
34712915 | Rapamycin recruits SIRT2 for FKBP12 deacetylation during mTOR activity modulation in innate immunity. | 2021 Nov 19 |
2 |
| 15 |
34801827 | Design, synthesis and biological evaluation of a novel spiro oxazolidinedione as potent p300/CBP HAT inhibitor for the treatment of ovarian cancer. | 2021 Dec 15 |
1 |
| 16 |
31531877 | CBP-triggered KDM2B acetylation accelerates the carcinogenesis of colon cancer. | 2020 Mar |
1 |
| 17 |
31713888 | Novel genetic variants in HDAC2 and PPARGC1A of the CREB-binding protein pathway predict survival of non-small-cell lung cancer. | 2020 Jan |
2 |
| 18 |
32173363 | A novel histone acetyltransferase inhibitor A485 improves sensitivity of non-small-cell lung carcinoma cells to TRAIL. | 2020 May |
1 |
| 19 |
32181984 | Early Drug-Discovery Efforts towards the Identification of EP300/CBP Histone Acetyltransferase (HAT) Inhibitors. | 2020 Jun 4 |
1 |
| 20 |
32314924 | Discovery, Structure-Activity Relationship, and Biological Activity of Histone-Competitive Inhibitors of Histone Acetyltransferases P300/CBP. | 2020 May 14 |
1 |
| 21 |
32527012 | SIRT7 Deacetylates STRAP to Regulate p53 Activity and Stability. | 2020 Jun 9 |
2 |
| 22 |
32559581 | Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain. | 2020 Aug |
2 |
| 23 |
32703935 | Deacetylation of HSD17B10 by SIRT3 regulates cell growth and cell resistance under oxidative and starvation stresses. | 2020 Jul 23 |
1 |
| 24 |
32882416 | Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors. | 2020 Nov 15 |
1 |
| 25 |
30856481 | CBP/p300 in brain development and plasticity: disentangling the KAT's cradle. | 2019 Dec |
4 |
| 26 |
30962627 | Bromodomain inhibition of the coactivators CBP/EP300 facilitate cellular reprogramming. | 2019 May |
1 |
| 27 |
31515273 | Structural and mechanistic insights into the interaction of the circadian transcription factor BMAL1 with the KIX domain of the CREB-binding protein. | 2019 Nov 8 |
1 |
| 28 |
29453984 | GATA3 acetylation at K119 by CBP inhibits cell migration and invasion in lung adenocarcinoma. | 2018 Mar 4 |
1 |
| 29 |
29531159 | Acetylation within the N- and C-Terminal Domains of Src Regulates Distinct Roles of STAT3-Mediated Tumorigenesis. | 2018 Jun 1 |
3 |
| 30 |
29758466 | Structural dynamics and quantum mechanical aspects of shikonin derivatives as CREBBP bromodomain inhibitors. | 2018 Aug |
2 |
| 31 |
30072621 | Inhibitor of CBP Histone Acetyltransferase Downregulates p53 Activation and Facilitates Methylation at Lysine 27 on Histone H3. | 2018 Aug 2 |
1 |
| 32 |
27979926 | CREBBP knockdown enhances RAS/RAF/MEK/ERK signaling in Ras pathway mutated acute lymphoblastic leukemia but does not modulate chemotherapeutic response. | 2017 Apr |
1 |
| 33 |
27989401 | CBP/p300 Bromodomains Regulate Amyloid-like Protein Aggregation upon Aberrant Lysine Acetylation. | 2017 Jan 19 |
1 |
| 34 |
28329675 | Trimethylation and Acetylation of β-Catenin at Lysine 49 Represent Key Elements in ESC Pluripotency. | 2017 Mar 21 |
1 |
| 35 |
28416608 | Hyper-O-GlcNAcylation activates nuclear factor κ-light-chain-enhancer of activated B cells (NF-κB) signaling through interplay with phosphorylation and acetylation. | 2017 Jun 2 |
2 |
| 36 |
27304234 | Correction to Protein Lysine Acetylation by p300/CBP. | 2016 Jul 27 |
1 |
| 37 |
27332697 | Modulation of p300/CBP Acetylation of Nucleosomes by Bromodomain Ligand I-CBP112. | 2016 Jul 12 |
1 |
| 38 |
27380996 | CBP/p300 acetyltransferase activity in hematologic malignancies. | 2016 Sep |
1 |
| 39 |
27462461 | A genome-scale CRISPR-Cas9 screening method for protein stability reveals novel regulators of Cdc25A. | 2016 |
1 |
| 40 |
27647933 | Wnt/β-catenin-dependent acetylation of Pygo2 by CBP/p300 histone acetyltransferase family members. | 2016 Nov 15 |
1 |
| 41 |
27814427 | Cation-π interactions in CREBBP bromodomain inhibition: an electrostatic model for small-molecule binding affinity and selectivity. | 2016 Nov 22 |
1 |
| 42 |
28002468 | Conserved Lysine Acetylation within the Microtubule-Binding Domain Regulates MAP2/Tau Family Members. | 2016 |
1 |
| 43 |
25594381 | Protein lysine acetylation by p300/CBP. | 2015 Mar 25 |
1 |
| 44 |
25941038 | CBP-Dependent memory consolidation in the prefrontal cortex supports object-location learning. | 2015 Dec |
1 |
| 45 |
26405459 | Post transcriptional control of the epigenetic stem cell regulator PLZF by sirtuin and HDAC deacetylases. | 2015 |
1 |
| 46 |
24361270 | Structural insights into acetylated-histone H4 recognition by the bromodomain-PHD finger module of human transcriptional coactivator CBP. | 2014 Feb 4 |
1 |
| 47 |
24616510 | Binding of the histone chaperone ASF1 to the CBP bromodomain promotes histone acetylation. | 2014 Mar 25 |
1 |
| 48 |
24939902 | CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis. | 2014 Jul |
4 |
| 49 |
25314079 | Acetylation of snail modulates the cytokinome of cancer cells to enhance the recruitment of macrophages. | 2014 Oct 13 |
2 |
| 50 |
23322770 | Reversible acetylation regulates salt-inducible kinase (SIK2) and its function in autophagy. | 2013 Mar 1 |
1 |