Spermine

spermidine/spermine N1-acetyltransferase 1 ; Homo sapiens







55 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34871830 Arabidopsis N-acetyltransferase activity 2 preferentially acetylates 1,3-diaminopropane and thialysine. 2022 Jan 1 1
2 33566220 Novel lnc-HZ03 and miR-hz03 promote BPDE-induced human trophoblastic cell apoptosis and induce miscarriage by upregulating p53/SAT1 pathway. 2021 Dec 1
3 34217652 The metabolic role of spermidine in obesity: Evidence from cells to community. 2021 Jul-Aug 1
4 32493979 Polyamine regulation of ion channel assembly and implications for nicotinic acetylcholine receptor pharmacology. 2020 Jun 3 1
5 33002680 Polyamine regulation of porcine reproductive and respiratory syndrome virus infection depends on spermidine-spermine acetyltransferase 1. 2020 Nov 4
6 30281855 Polyamine-independent growth and biofilm formation, and functional spermidine/spermine N-acetyltransferases in Staphylococcus aureus and Enterococcus faecalis. 2019 Jan 5
7 27901475 Spermidine/spermine N1-acetyltransferase regulates cell growth and metastasis via AKT/β-catenin signaling pathways in hepatocellular and colorectal carcinoma cells. 2017 Jan 3 1
8 27427208 Interferon-Induced Spermidine-Spermine Acetyltransferase and Polyamine Depletion Restrict Zika and Chikungunya Viruses. 2016 Aug 10 1
9 27698118 Activation of SAT1 engages polyamine metabolism with p53-mediated ferroptotic responses. 2016 Nov 1 1
10 25849284 Depletion of the polyamines spermidine and spermine by overexpression of spermidine/spermine N¹-acetyltransferase 1 (SAT1) leads to mitochondria-mediated apoptosis in mammalian cells. 2015 Jun 15 2
11 23771789 Polyamine catabolism in carcinogenesis: potential targets for chemotherapy and chemoprevention. 2014 Mar 1
12 24649071 Lack of evidence for the association of ornithine decarboxylase (+316 G>A), spermidine/spermine acetyl transferase (-1415 T>C) gene polymorphisms with calcium oxalate stone disease. 2014 Jan 2
13 23345430 Depletion of cellular polyamines, spermidine and spermine, causes a total arrest in translation and growth in mammalian cells. 2013 Feb 5 8
14 23903781 Modulation of the expression of folate cycle enzymes and polyamine metabolism by berberine in cisplatin-sensitive and -resistant human ovarian cancer cells. 2013 Oct 1
15 22579641 Chemically induced oxidative stress increases polyamine levels by activating the transcription of ornithine decarboxylase and spermidine/spermine-N1-acetyltransferase in human hepatoma HUH7 cells. 2012 Sep 1
16 20443003 Combination effects of platinum drugs and N1, N11 diethylnorspermine on spermidine/spermine N1-acetyltransferase, polyamines and growth inhibition in A2780 human ovarian carcinoma cells and their oxaliplatin and cisplatin-resistant variants. 2011 Feb 1
17 22001988 Association between remote organ injury and tissue polyamine homeostasis in acute experimental pancreatitis - treatment with a polyamine analogue bismethylspermine. 2011 1
18 20212040 Suppression of exogenous gene expression by spermidine/spermine N1-acetyltransferase 1 (SSAT1) cotransfection. 2010 May 14 1
19 19152344 Profiling brain expression of the spermidine/spermine N1-acetyltransferase 1 (SAT1) gene in suicide. 2009 Oct 5 1
20 18089555 Polyamine acetylation modulates polyamine metabolic flux, a prelude to broader metabolic consequences. 2008 Feb 15 3
21 18430370 Adenovirus-mediated expression of SSAT inhibits colorectal cancer cell growth in vitro. 2008 May 2
22 18480266 The alpha9beta1 integrin enhances cell migration by polyamine-mediated modulation of an inward-rectifier potassium channel. 2008 May 20 1
23 18571584 A polyamine analog bismethylspermine ameliorates severe pancreatitis induced by intraductal infusion of taurodeoxycholate. 2008 Jul 2
24 18690703 The crystal structure of spermidine/spermine N1-acetyltransferase in complex with spermine provides insights into substrate binding and catalysis. 2008 Sep 2 3
25 17382924 Role of polyamines in myocardial ischemia/reperfusion injury and their interactions with nitric oxide. 2007 May 21 1
26 17516632 Mechanistic and structural analysis of human spermidine/spermine N1-acetyltransferase. 2007 Jun 19 2
27 16452302 Genetic manipulation of polyamine catabolism in rodents. 2006 Feb 1
28 16455797 Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target. 2006 Feb 14 2
29 16809818 Polyamine-regulated unproductive splicing and translation of spermidine/spermine N1-acetyltransferase. 2006 Aug 1
30 15905201 Spermidine/spermine N1-acetyltransferase transient overexpression restores sensitivity of resistant human ovarian cancer cells to N1,N12-bis(ethyl)spermine and to cisplatin. 2005 Oct 1
31 14592538 Cisplatin-resistance modulates the effect of protein synthesis inhibitors on spermidine/spermine N(1)-acetyltransferase expression. 2004 Jan 1
32 15133083 Polyamine metabolism in a member of the phylum Microspora (Encephalitozoon cuniculi): effects of polyamine analogues. 2004 May 3
33 15213272 Overexpression of SSAT in kidney cells recapitulates various phenotypic aspects of kidney ischemia-reperfusion injury. 2004 Jul 1
34 15283699 Spermidine/spermine-N1-acetyltransferase-2 (SSAT2) acetylates thialysine and is not involved in polyamine metabolism. 2004 Nov 15 1
35 15492267 Spermine acts as a negative regulator of macrophage differentiation in human myeloid leukemia cells. 2004 Oct 15 1
36 12477380 Genomic identification and biochemical characterization of the mammalian polyamine oxidase involved in polyamine back-conversion. 2003 Feb 15 2
37 12798351 Expression of spermidine/spermine N1-acetyltransferase in HeLa cells is regulated by amino acid sufficiency. 2003 Sep 1
38 12803540 Genomic identification and biochemical characterization of a second spermidine/spermine N1-acetyltransferase. 2003 Aug 1 4
39 14573765 Small interfering RNA suppression of polyamine analog-induced spermidine/spermine n1-acetyltransferase. 2003 Nov 2
40 11709547 Altered levels of growth-related and novel gene transcripts in reproductive and other tissues of female mice overexpressing spermidine/spermine N1-acetyltransferase (SSAT). 2002 Feb 1 1
41 11846806 Rapid caspase-dependent cell death in cultured human breast cancer cells induced by the polyamine analogue N(1),N(11)-diethylnorspermine. 2002 Feb 4
42 12141946 Identification and characterization of a novel flavin-containing spermine oxidase of mammalian cell origin. 2002 Nov 1 2
43 11166157 Differential induction of spermidine/spermine N1-acetyltransferase activity in cisplatin-sensitive and -resistant ovarian cancer cells in response to N1,N12-bis(ethyl)spermine involves transcriptional and post-transcriptional regulation. 2001 Jan 2
44 11171097 Manipulation of the expression of regulatory genes of polyamine metabolism results in specific alterations of the cell-cycle progression. 2001 Feb 15 1
45 9480841 Significant increases in the steady states of putrescine and spermidine/spermine N1-acetyltransferase mRNA in HeLa cells accompanied by growth arrest. 1998 Feb 13 1
46 9224814 Structural basis for differential induction of spermidine/spermine N1-acetyltransferase activity by novel spermine analogs. 1997 Jul 3
47 8706937 Differential post-transcriptional control of ornithine decarboxylase and spermidine-spermine N1-acetyltransferase by polyamines. 1996 Aug 5 1
48 8916930 Effects of polyamines, polyamine analogs, and inhibitors of protein synthesis on spermidine-spermine N1-acetyltransferase gene expression. 1996 Nov 12 1
49 7982492 Effects of transient expression of spermidine/spermine N1-acetyltransferase in COS cells. 1994 Nov 28 3
50 8360194 Polyamine and polyamine analog regulation of spermidine/spermine N1-acetyltransferase in MALME-3M human melanoma cells. 1993 Sep 5 2