Bosentan

endothelin receptor type A ; Rattus norvegicus







70 Article(s)
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1 34894846 Endothelin receptor type A is involved in the development of oxaliplatin-induced mechanical allodynia and cold allodynia acting through spinal and peripheral mechanisms in rats. 2021 Jan-Dec 1
2 31600800 Investigation of Bosentan's Effects on Pulmonary Contusion Created by Blunt Thoracic Trauma in Rats. 2020 Feb 1
3 29226623 Distortion of KB estimates of endothelin-1 ETA and ETB receptor antagonists in pulmonary arteries: Possible role of an endothelin-1 clearance mechanism. 2017 Dec 3
4 26663321 Endothelin regulates intermittent hypoxia-induced lipolytic remodelling of adipose tissue and phosphorylation of hormone-sensitive lipase. 2016 Mar 15 2
5 24918345 Endothelin receptor inhibition with bosentan delays onset of liver injury in streptozotocin-induced diabetic condition. 2015 May 1
6 25847324 The lung endothelin system: a potent therapeutic target with bosentan for the amelioration of lung alterations in a rat model of diabetes mellitus. 2015 Sep 2
7 24389822 Bladder endothelin-1 receptor binding of bosentan and ambrisentan. 2014 1
8 24833743 The ocular endothelin system: a novel target for the treatment of endotoxin-induced uveitis with bosentan. 2014 May 15 1
9 24836182 Efficacy of bosentan, a dual ETA and ETB endothelin receptor antagonist, in experimental diabetes induced vascular endothelial dysfunction and associated dementia in rats. 2014 Sep 2
10 22899584 Directly acting drugs prostacyclin or nitroglycerine and endothelin receptor blocker bosentan improve cell engraftment in rodent liver. 2013 Jan 1
11 23988169 Electrophysiological effects of bosentan in rats with induced cerebral ischemia-reperfusion. 2013 Aug 1
12 21920972 Torcetrapib impairs endothelial function in hypertension. 2012 Jul 1
13 22407503 Transforming growth factor-alpha induces endothelin receptor A expression in osteoarthritis. 2012 Sep 1
14 22994521 Effect of endothelin receptor antagonist bosentan on chronic hypoxia-induced inflammation and chemoafferent neuron adaptation in rat carotid body. 2012 Sep 1
15 21205912 Endothelial endothelin B receptor-mediated prevention of cerebrovascular remodeling is attenuated in diabetes because of up-regulation of smooth muscle endothelin receptors. 2011 Apr 1
16 19829016 Effects of an endothelin receptor antagonist on a model of hypertensive retinopathy. 2010 1
17 19897563 Endothelin-1 receptor antagonists prevent the development of pulmonary emphysema in rats. 2010 Apr 1
18 19391127 Leptin and endothelin-1 mediated increased extracellular matrix protein production and cardiomyocyte hypertrophy in diabetic heart disease. 2009 Jul 1
19 16563629 Orofacial cold hyperalgesia due to infraorbital nerve constriction injury in rats: reversal by endothelin receptor antagonists but not non-steroidal anti-inflammatory drugs. 2006 Jul 1
20 16601312 Influence of renal denervation on renal effects of acute nitric oxide and ETA/ETB receptor inhibition in conscious normotensive rats. 2006 Mar 1
21 16807127 Early-onset endothelin receptor blockade in hypertensive heterozygous Ren-2 rats. 2006 Sep 1
22 17111027 Effects of endothelin receptor blockade on hypervasoreactivity in streptozotocin-diabetic rats: vessel-specific involvement of thromboxane A2. 2006 Aug-Sep 1
23 15870840 Endothelin A and B receptor antagonist bosentan reduces postischemic myocardial injury in the rat: critical timing of administration. 2005 Mar 1
24 14638626 Role of membrane potential and expression of endothelial factors in restenosis after angioplasty in SHR. 2004 Jan 1
25 14693683 Nitric oxide mediates protective effect of endothelin receptor antagonism during myocardial ischemia and reperfusion. 2004 May 1
26 15093706 Endothelin-3 induced mesenteric vasoconstriction and PMN infiltration in the rat small intestine: role of endothelin receptors. 2004 Jun 15 1
27 15180799 Analysis of ET-A and ET-B receptors using an isolated perfused rat lung preparation. 2004 Jun 1
28 12617929 The use of sulfonylamido pyrimidines incorporating an unsaturated side chain as endothelin receptor antagonists. 2003 Mar 10 1
29 12181591 The role of endothelin in oxygen-induced contraction of the ductus arteriosus in rabbit and rat fetuses. 2002 Jul 1
30 11156582 Combined blockade of endothelin-1 and thromboxane A(2) receptors against postischaemic contractile dysfunction in rat hearts. 2001 Jan 1
31 11383615 Ethenesulfonamide derivatives, a novel class of orally active endothelin-A receptor antagonists. 2001 May 4
32 10726713 Receptor- and non-receptor-mediated clearance of big-endothelin and endothelin-1: differential effects of acute and chronic ETA receptor blockade. 2000 Mar 1
33 10961375 Differential effects of the mixed ET(A)/ET(B)-receptor antagonist bosentan on endothelin-induced bronchoconstriction, vasoconstriction and prostacyclin release. 2000 Aug 3
34 9539881 Regional variation in appearance of vascular contractile endothelin-B receptors following organ culture. 1998 Jan 1
35 9731554 Beneficial hemodynamic effects of bosentan, a mixed ET(A) and ET(B) receptor antagonist, in portal hypertensive rats. 1998 Sep 1
36 9789575 Contribution of endothelin to the coronary vasoconstriction in the isolated rat heart induced by nitric oxide synthase inhibition. 1998 Aug 1
37 9830507 Endothelin: role in hypertension. 1998 1
38 15992023 The pharmacology of bosentan. 1998 Jul 1
39 8978330 Combined inhibition of endothelin and angiotensin II receptors blocks volume load-induced cardiac hormone release. 1997 Jan 1
40 9107557 Hypoxic contractile response in isolated rat thoracic aorta: role of endothelium, extracellular calcium and endothelin. 1997 1
41 9146895 Trophic effect of angiotensin II in neonatal rat cardiomyocytes: role of endothelin-1 and non-myocyte cells. 1997 May 2
42 9176305 Endothelin-1 in rat endotoxemia: mRNA expression and vasoreactivity in pulmonary and systemic circulations. 1997 May 1
43 9201101 Effects of mixed ETA and ETB-receptor antagonist (Ro-47-0203) on hepatic microcirculation after warm ischemia. 1997 Jun 1
44 9386175 Endothelin-1 is involved in stretch-induced early activation of B-type natriuretic peptide gene expression in atrial but not in ventricular myocytes: acute effects of mixed ET(A)/ET(B) and AT1 receptor antagonists in vivo and in vitro. 1997 Nov 4 1
45 9444527 Evaluation of bosentan, pinacidil and nitroprusside on human pulmonary arteries: comparison with rat pulmonary arteries. 1997 1
46 8602109 Selective and non-selective ET antagonists reveal an ETB receptors mediated ET-1-induced behavioural effect in conscious rats. 1996 1
47 8640984 Endothelin-1 is involved in norepinephrine-induced ventricular hypertrophy in vivo. Acute effects of bosentan, an orally active, mixed endothelin ETA and ETB receptor antagonist. 1996 Jun 1 1
48 8662290 Different endothelin receptor subtypes are involved in phospholipid signalling in the proximal tubule of rat kidney. 1996 Jun 1
49 8689641 Function and expression of endothelin receptor subtypes in the kidneys of spontaneously hypertensive rats. 1996 Apr 1
50 8828566 Intrastriatal injection of endothelin evokes dopaminergic turning behaviour in rats through activation of the ETB receptor. 1996 Jun 17 1