Morphine

solute carrier family 22 member 1 ; Homo sapiens







20 Article(s)
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Title
Pub. Year
#Total Relationships
1 34599645 No significant influence of OCT1 genotypes on the pharmacokinetics of morphine in adult surgical patients. 2022 Jan 2
2 33847389 Pharmacogenomics and Morphine. 2021 Sep 1
3 33967805 Transport of Drugs and Endogenous Compounds Mediated by Human OCT1: Studies in Single- and Double-Transfected Cell Models. 2021 3
4 31630405 Quantitative Proteomics and Mechanistic Modeling of Transporter-Mediated Disposition in Nonalcoholic Fatty Liver Disease. 2020 May 1
5 32090339 Influence of MRP3 Genetics and Hepatic Expression Ontogeny for Morphine Disposition in Neonatal and Pediatric Patients. 2020 Aug 1
6 30300922 Influence of OCT1 Ontogeny and Genetic Variation on Morphine Disposition in Critically Ill Neonates: Lessons From PBPK Modeling and Clinical Study. 2019 Mar 2
7 31597043 Opioids as Substrates and Inhibitors of the Genetically Highly Variable Organic Cation Transporter OCT1. 2019 Nov 14 1
8 29920988 PBPK Model of Morphine Incorporating Developmental Changes in Hepatic OCT1 and UGT2B7 Proteins to Explain the Variability in Clearances in Neonates and Small Infants. 2018 Jul 2
9 29994939 Genetics and genomics in postoperative pain and analgesia. 2018 Oct 2
10 30361780 Irinotecan Alters the Disposition of Morphine Via Inhibition of Organic Cation Transporter 1 (OCT1) and 2 (OCT2). 2018 Oct 25 8
11 30544975 Impact of Promoter Polymorphisms on the Transcriptional Regulation of the Organic Cation Transporter OCT1 (SLC22A1). 2018 Dec 11 3
12 27935268 Characterization of Contributing Factors to Variability in Morphine Clearance Through PBPK Modeling Implemented With OCT1 Transporter. 2017 Feb 4
13 28063968 Lack of genetic association between OCT1, ABCB1, and UGT2B7 variants and morphine pharmacokinetics. 2017 Mar 1 1
14 28470102 OCT1 genetic variants are associated with postoperative morphine-related adverse effects in children. 2017 May 7
15 29061087 OCT1 pharmacogenetics in pain management: is a clinical application within reach? 2017 Nov 1
16 29236753 Effects of genetic polymorphisms on the OCT1 and OCT2-mediated uptake of ranitidine. 2017 3
17 25155932 ABCC3 and OCT1 genotypes influence pharmacokinetics of morphine in children. 2014 Jul 4
18 23835420 Morphine is a substrate of the organic cation transporter OCT1 and polymorphisms in OCT1 gene affect morphine pharmacokinetics after codeine administration. 2013 Sep 1 10
19 23859569 OCT1 genetic variants influence the pharmacokinetics of morphine in children. 2013 Jul 3
20 23922447 Hepatocyte nuclear factor 1 regulates the expression of the organic cation transporter 1 via binding to an evolutionary conserved region in intron 1 of the OCT1 gene. 2013 Oct 1