Cimetidine

solute carrier family 22 member 1 ; Homo sapiens







8 Article(s)
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1 34064886 A Whole-Body Physiologically Based Pharmacokinetic Model Characterizing Interplay of OCTs and MATEs in Intestine, Liver and Kidney to Predict Drug-Drug Interactions of Metformin with Perpetrators. 2021 May 11 1
2 26702643 The Nonmetabolized β-Blocker Nadolol Is a Substrate of OCT1, OCT2, MATE1, MATE2-K, and P-Glycoprotein, but Not of OATP1B1 and OATP1B3. 2016 Feb 1 1
3 27019345 Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug-drug interactions. 2016 Jun 10 2
4 26552145 [Establishment of MDCK cell models expressing human MATE1 or co-expressing with human OCT1 or OCT2]. 2015 Jul 1
5 22072731 Competitive inhibition of the luminal efflux by multidrug and toxin extrusions, but not basolateral uptake by organic cation transporter 2, is the likely mechanism underlying the pharmacokinetic drug-drug interactions caused by cimetidine in the kidney. 2012 Feb 2
6 20977453 Modulation of drug block of the cardiac potassium channel KCNA5 by the drug transporters OCTN1 and MDR1. 2010 Nov 2
7 19357179 Organic cation transporters OCT1, 2, and 3 mediate high-affinity transport of the mutagenic vital dye ethidium in the kidney proximal tubule. 2009 Jun 1
8 17614008 Comparison of the kinetic characteristics of inhibitory effects exerted by biguanides and H2-blockers on human and rat organic cation transporter-mediated transport: Insight into the development of drug candidates. 2007 Jun 1