| 1 |
34987222 | Structural insights into inhibitor regulation of the DNA repair protein DNA-PKcs. | 2022 Jan |
1 |
| 2 |
31502598 | Real-time surface plasmon resonance monitoring of site-specific phosphorylation of p53 protein and its interaction with MDM2 protein. | 2019 Oct 21 |
1 |
| 3 |
25876968 | [Inhibitors of DNA-dependent protein kinase promote p53-independent apoptosis induced by 1, 4-benzoquinone in HL60 cells]. | 2015 Jan |
3 |
| 4 |
24953561 | Wortmannin potentiates the combined effect of etoposide and cisplatin in human glioma cells. | 2014 Aug |
4 |
| 5 |
22982065 | A role of DNA-dependent protein kinase for the activation of AMP-activated protein kinase in response to glucose deprivation. | 2012 Dec |
1 |
| 6 |
21567080 | Priming and potentiation of DNA damage response by fibronectin in human colon cancer cells and tumor-derived myofibroblasts. | 2011 Aug |
1 |
| 7 |
19697154 | BCR/ABL downregulates DNA-PK(CS)-dependent and upregulates backup non-homologous end joining in leukemic cells. | 2010 Jun |
1 |
| 8 |
20824055 | Topoisomerase II-mediated DNA damage is differently repaired during the cell cycle by non-homologous end joining and homologous recombination. | 2010 Sep 2 |
1 |
| 9 |
20878124 | Replication-dependent γ-H2AX formation is involved in docetaxel-induced apoptosis in NSCLC A549 cells. | 2010 Nov |
1 |
| 10 |
21042768 | Inhibition of PI3 kinases enhances the sensitivity of non-small cell lung cancer cells to ionizing radiation. | 2010 Dec |
3 |
| 11 |
19372586 | DNA-dependent protein kinase (DNA-PK)-dependent cisplatin-induced loss of nucleolar facilitator of chromatin transcription (FACT) and regulation of cisplatin sensitivity by DNA-PK and FACT. | 2009 Apr |
1 |
| 12 |
18813802 | Premature chromosome condensation reveals DNA-PK independent pathways of chromosome break repair. | 2008 Oct |
2 |
| 13 |
17674777 | [Effect of wortmannin on rejoining of telomeric DNA strand breaks]. | 2007 Jun |
2 |
| 14 |
16505093 | Interaction of the epidermal growth factor receptor and the DNA-dependent protein kinase pathway following gefitinib treatment. | 2006 Feb |
1 |
| 15 |
16510557 | Mechanisms of induction of cell cycle arrest and cell death by cryptolepine in human lung adenocarcinoma a549 cells. | 2006 May |
2 |
| 16 |
15389585 | Complex H2AX phosphorylation patterns by multiple kinases including ATM and DNA-PK in human cells exposed to ionizing radiation and treated with kinase inhibitors. | 2005 Feb |
1 |
| 17 |
15718417 | Human chronic lymphocytic leukemia B cells can escape DNA damage-induced apoptosis through the nonhomologous end-joining DNA repair pathway. | 2005 Jun 15 |
2 |
| 18 |
16138421 | The effect of wortmannin on radiation-induced chromosome aberration formation in the radioresistant tumor cell line WiDr. | 2005 Aug |
2 |
| 19 |
14661061 | SU11752 inhibits the DNA-dependent protein kinase and DNA double-strand break repair resulting in ionizing radiation sensitization. | 2004 Jan 29 |
3 |
| 20 |
14991746 | Relationship between the radiosensitizing effect of wortmannin, DNA double-strand break rejoining, and p21WAF1 induction in human normal and tumor-derived cells. | 2004 Mar |
2 |
| 21 |
15164794 | Role of DNA-dependent protein kinase in the process of radiation-induced aberration formation. | 2004 Feb |
1 |
| 22 |
15211575 | Backup pathways of NHEJ are suppressed by DNA-PK. | 2004 Jul 1 |
3 |
| 23 |
12547193 | Coordinated assembly of Ku and p460 subunits of the DNA-dependent protein kinase on DNA ends is necessary for XRCC4-ligase IV recruitment. | 2003 Feb 7 |
1 |
| 24 |
12556332 | Role of DNA-PK in the process of aberration formation as studied in irradiated human glioblastoma cell lines M059K and M059J. | 2003 Jan |
5 |
| 25 |
12954774 | Biochemical evidence for Ku-independent backup pathways of NHEJ. | 2003 Sep 15 |
1 |
| 26 |
12956959 | DNA damage foci at dysfunctional telomeres. | 2003 Sep 2 |
1 |
| 27 |
12968928 | Wortmannin-enhanced X-ray-induced apoptosis of human T-cell leukemia MOLT-4 cells possibly through the JNK/SAPK pathway. | 2003 Oct |
1 |
| 28 |
14573792 | Interactive competition between homologous recombination and non-homologous end joining. | 2003 Oct |
2 |
| 29 |
14673873 | DNA end sequestration by DNA-dependent protein kinase and end joining of sterically constrained substrates in whole-cell extracts. | 2003 |
1 |
| 30 |
11864976 | The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c. | 2002 May 10 |
2 |
| 31 |
12065055 | Roles of DNA-dependent protein kinase and ATM in cell-cycle-dependent radiation sensitivity in human cells. | 2002 Jun |
1 |
| 32 |
12066222 | Low dose of wortmannin reduces radiosensitivity of human glioblastoma cells through the p53 pathway. | 2002 Jul-Aug |
1 |
| 33 |
12438258 | Selective inactivation of DNA-dependent protein kinase with antisense oligodeoxynucleotides: consequences for the rejoining of radiation-induced DNA double-strand breaks and radiosensitivity of human cancer cell lines. | 2002 Nov 15 |
3 |
| 34 |
11160753 | EBNA-LP associates with cellular proteins including DNA-PK and HA95. | 2001 Mar |
2 |
| 35 |
11196174 | Nonhomologous end-joining of ionizing radiation-induced DNA double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2. | 2001 Jan 1 |
2 |
| 36 |
11243849 | Human rad21 gene, hHR21(SP), is downregulated by hypoxia in human tumor cells. | 2001 Mar |
3 |
| 37 |
11304695 | Unique pattern of ET-743 activity in different cellular systems with defined deficiencies in DNA-repair pathways. | 2001 May 15 |
1 |
| 38 |
11309379 | Accurate in vitro end joining of a DNA double strand break with partially cohesive 3'-overhangs and 3'-phosphoglycolate termini: effect of Ku on repair fidelity. | 2001 Jun 29 |
1 |
| 39 |
11389089 | Apoptotic triggers initiate translocations within the MLL gene involving the nonhomologous end joining repair system. | 2001 Jun 1 |
1 |
| 40 |
11571274 | ATM phosphorylates histone H2AX in response to DNA double-strand breaks. | 2001 Nov 9 |
1 |
| 41 |
11731442 | Replication protein A2 phosphorylation after DNA damage by the coordinated action of ataxia telangiectasia-mutated and DNA-dependent protein kinase. | 2001 Dec 1 |
2 |
| 42 |
10728683 | DNA-dependent protein kinase stimulates an independently active, nonhomologous, end-joining apparatus. | 2000 Mar 1 |
1 |
| 43 |
10771089 | Phosphatidylinositol 3-kinase inhibitors, Wortmannin or LY294002, inhibited accumulation of p21 protein after gamma-irradiation by stabilization of the protein. | 2000 Apr 17 |
1 |
| 44 |
10862623 | Heat and chemical shock potentiation of glucocorticoid receptor transactivation requires heat shock factor (HSF) activity. Modulation of HSF by vanadate and wortmannin. | 2000 Aug 25 |
2 |
| 45 |
11086175 | Potentiation of chemosensitivity in multidrug-resistant human leukemia CEM cells by inhibition of DNA-dependent protein kinase using wortmannin. | 2000 Nov |
5 |
| 46 |
11133044 | Poly(ADP-ribose) polymerase, a major determinant of early cell response to ionizing radiation. | 2000 Dec |
1 |
| 47 |
9952300 | Wortmannin sensitizes mammalian cells to radiation by inhibiting the DNA-dependent protein kinase-mediated rejoining of double-strand breaks. | 1999 Feb |
5 |
| 48 |
9972793 | DNA-PK-independent rejoining of DNA double-strand breaks in human cell extracts in vitro. | 1999 Jan |
1 |
| 49 |
10207623 | DNA-dependent protein kinase and related proteins. | 1999 |
1 |
| 50 |
10363977 | Competitive and noncompetitive inhibition of the DNA-dependent protein kinase. | 1999 Jun 1 |
4 |