2-(morpholin-4-yl)-benzo[h]chomen-4-one

protein kinase, DNA-activated, catalytic subunit ; Homo sapiens







4 Article(s)
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1 23392706 Inhibition of DNA-dependent protein kinase catalytic subunit by small molecule inhibitor NU7026 sensitizes human leukemic K562 cells to benzene metabolite-induced apoptosis. 2013 Feb 1
2 17351105 Chlorambucil cytotoxicity in malignant B lymphocytes is synergistically increased by 2-(morpholin-4-yl)-benzo[h]chomen-4-one (NU7026)-mediated inhibition of DNA double-strand break repair via inhibition of DNA-dependent protein kinase. 2007 Jun 1
3 15718417 Human chronic lymphocytic leukemia B cells can escape DNA damage-induced apoptosis through the nonhomologous end-joining DNA repair pathway. 2005 Jun 15 2
4 15010369 A novel DNA-dependent protein kinase inhibitor, NU7026, potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia. 2004 Jun 15 1