Doxorubicin

protein kinase, DNA-activated, catalytic subunit ; Homo sapiens







20 Article(s)
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Title
Pub. Year
#Total Relationships
1 35149547 The DNA-PK Inhibitor AZD7648 Sensitizes Patient-Derived Ovarian Cancer Xenografts to Pegylated Liposomal Doxorubicin and Olaparib Preventing Abdominal Metastases. 2022 Apr 1 1
2 34330845 The PI3K/mTOR Inhibitor Ompalisib Suppresses Nonhomologous End Joining and Sensitizes Cancer Cells to Radio- and Chemotherapy. 2021 Nov 1
3 30326402 Novel quinazolin-4-one derivatives as potentiating agents of doxorubicin cytotoxicity. 2019 Feb 1
4 31699977 AZD7648 is a potent and selective DNA-PK inhibitor that enhances radiation, chemotherapy and olaparib activity. 2019 Nov 7 1
5 31759252 APC loss affects DNA damage repair causing doxorubicin resistance in breast cancer cells. 2019 Dec 2
6 29574068 Natural product toosendanin reverses the resistance of human breast cancer cells to adriamycin as a novel PI3K inhibitor. 2018 Jun 1
7 30258062 Mutagenic assessment of chemotherapy and Smac mimetic drugs in cells with defective DNA damage response pathways. 2018 Sep 26 1
8 28821159 Inhibition of DNA-PK enhances chemosensitivity of B-cell precursor acute lymphoblastic leukemia cells to doxorubicin. 2017 Oct 4
9 25480831 DNA-PK-A candidate driver of hepatocarcinogenesis and tissue biomarker that predicts response to treatment and survival. 2015 Feb 15 1
10 24292814 DNA-PK inhibition by NU7441 sensitizes breast cancer cells to ionizing radiation and doxorubicin. 2014 Jan 1
11 19633683 The pyridinylfuranopyrimidine inhibitor, PI-103, chemosensitizes glioblastoma cells for apoptosis by inhibiting DNA repair. 2009 Oct 8 1
12 18508926 DNA-ligase IV and DNA-protein kinase play a critical role in deficient caspases activation in apoptosis-resistant cancer cells by using doxorubicin. 2008 Aug 4
13 32038792 Activation Mechanism of Protein Kinase B by DNA-dependent Protein Kinase Involved in the DNA Repair System. 2008 Sep 1
14 14966265 ATM and the catalytic subunit of DNA-dependent protein kinase activate NF-kappaB through a common MEK/extracellular signal-regulated kinase/p90(rsk) signaling pathway in response to distinct forms of DNA damage. 2004 Mar 2
15 10854324 Nitric oxide upregulates expression of DNA-PKcs to protect cells from DNA-damaging anti-tumour agents. 2000 Jun 1
16 10454483 Glutathione conjugate interactions with DNA-dependent protein kinase. 1999 Sep 1
17 9679555 Coordinate changes in expression of protective genes in drug-resistant cells. 1998 Apr 24 1
18 9685611 Increased expression of DNA-dependent protein kinase confers resistance to adriamycin. 1998 Jul 23 5
19 9406235 Importance of glutathione and associated enzymes in drug response. 1997 3
20 8619835 DNA-dependent protein kinase inhibitor (OK-1035) suppresses p21 expression in HCT116 cells containing wild-type p53 induced by adriamycin. 1996 Apr 16 1