1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine

solute carrier family 6 member 3 ; Homo sapiens







30 Article(s)
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1 34286493 Converging dopaminergic neurotoxicity mechanisms of antipsychotics, methamphetamine and levodopa. 2021 Jul 1
2 33172035 Ellagic Acid Prevents Dopamine Neuron Degeneration from Oxidative Stress and Neuroinflammation in MPTP Model of Parkinson's Disease. 2020 Nov 6 2
3 31325476 Phytic acid attenuates upregulation of GSK-3β and disturbance of synaptic vesicle recycling in MPTP-induced Parkinson's disease models. 2019 Oct 1
4 28754312 Exercise in an animal model of Parkinson's disease: Motor recovery but not restoration of the nigrostriatal pathway. 2017 Sep 17 2
5 25989025 Prevention of the degeneration of human dopaminergic neurons in an astrocyte co-culture system allowing endogenous drug metabolism. 2015 Aug 1
6 25108180 Increased DAT binding in the early stage of the dopaminergic lesion: a longitudinal [11C]PE2I binding study in the MPTP-monkey. 2014 Nov 15 5
7 23322189 Metallobiology of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity. 2013 Feb 1
8 23468413 Coordinated expression of dopamine transporter and vesicular monoamine transporter in the primate striatum during development. 2013 Sep 1
9 23106974 MPTP animal model of Parkinsonism: dopamine cell death or only tyrosine hydroxylase impairment? A study using PET imaging, autoradiography, and immunohistochemistry in the cat. 2012 Nov 1
10 20488205 Objective and quantitative evaluation of motor function in a monkey model of Parkinson's disease. 2010 Jul 15 2
11 21124922 Dopamine transporter binding is unaffected by L-DOPA administration in normal and MPTP-treated monkeys. 2010 Nov 22 2
12 19527435 Evidence for a dopaminergic innervation of the pedunculopontine nucleus in monkeys, and its drastic reduction after MPTP intoxication. 2009 Aug 1
13 17503735 Differential loss of presynaptic dopaminergic markers in Parkinsonian monkeys. 2007 1
14 16809432 Developmental exposure to the pesticide dieldrin alters the dopamine system and increases neurotoxicity in an animal model of Parkinson's disease. 2006 Aug 1
15 16882311 Chronic oral nicotine treatment protects against striatal degeneration in MPTP-treated primates. 2006 Sep 1
16 15614202 Mechanisms of MPTP toxicity and their implications for therapy of Parkinson's disease. 2005 Jan 9
17 16141438 Paraquat neurotoxicity is distinct from that of MPTP and rotenone. 2005 Nov 2
18 15480838 Dopamine transporter: involvement in selective dopaminergic neurotoxicity and degeneration. 2004 Oct 1
19 12040046 Peroxynitrite inactivates the human dopamine transporter by modification of cysteine 342: potential mechanism of neurotoxicity in dopamine neurons. 2002 Jun 1 1
20 10830409 Relationship among nigrostriatal denervation, parkinsonism, and dyskinesias in the MPTP primate model. 2000 May 1
21 10854757 Expression of D(3) receptor messenger RNA and binding sites in monkey striatum and substantia nigra after nigrostriatal degeneration: effect of levodopa treatment. 2000 1
22 10330690 Regional and temporal expression of the peripheral benzodiazepine receptor in MPTP neurotoxicity. 1999 Mar 1
23 10418689 Global variation of a 40-bp VNTR in the 3'-untranslated region of the dopamine transporter gene (SLC6A3). 1999 Jul 15 2
24 10494878 Potencies of haloperidol metabolites as inhibitors of the human noradrenaline, dopamine and serotonin transporters in transfected COS-7 cells. 1999 Aug 1
25 9380062 Association of a polymorphism in the dopamine-transporter gene with Parkinson's disease. 1997 Sep 1
26 8667208 Catecholamine transporters and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity: studies comparing the cloned human noradrenaline and human dopamine transporter. 1996 Jun 1
27 8576447 Subsets of midbrain dopaminergic neurons in monkeys are distinguished by different levels of mRNA for the dopamine transporter: comparison with the mRNA for the D2 receptor, tyrosine hydroxylase and calbindin immunoreactivity. 1995 Nov 20 3
28 8674469 [The dopamine transporter: characterization and physiopathologic implications]. 1995 Nov-Dec 1
29 7925828 Novel radioligands for the dopamine transporter demonstrate the presence of intrastriatal nigral grafts in the MPTP-treated monkey: correlation with improved behavioral function. 1994 Apr 1
30 8149355 Molecular, functional and biochemical characteristics of the dopamine transporter: regional differences and clinical relevance. 1994 Feb 4