Zinc

solute carrier family 6 member 3 ; Homo sapiens







19 Article(s)
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Pub. Year
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1 28096460 Occupancy of the Zinc-binding Site by Transition Metals Decreases the Substrate Affinity of the Human Dopamine Transporter by an Allosteric Mechanism. 2017 Mar 10 4
2 25741436 Zn(2+) reverses functional deficits in a de novo dopamine transporter variant associated with autism spectrum disorder. 2015 4
3 26504078 Dual Action of Zn2+ on the Transport Cycle of the Dopamine Transporter. 2015 Dec 25 8
4 20806985 Role of zinc in the pathogenesis of attention-deficit hyperactivity disorder: implications for research and treatment. 2010 Sep 1
5 19000913 Zinc regulates the dopamine transporter in a membrane potential and chloride dependent manner. 2009 Feb 8
6 19098122 A juxtamembrane mutation in the N terminus of the dopamine transporter induces preference for an inward-facing conformation. 2009 Mar 1
7 17408612 Differential effects of Zn2+ on the kinetics and cocaine inhibition of dopamine transport by the human and rat dopamine transporters. 2007 Jun 22 6
8 16129457 Intramolecular cross-linking in a bacterial homolog of mammalian SLC6 neurotransmitter transporters suggests an evolutionary conserved role of transmembrane segments 7 and 8. 2005 Nov 1
9 14680760 Zn2+ modulates currents generated by the dopamine transporter: parallel effects on amphetamine-induced charge transfer and release. 2004 Feb 1
10 12773538 Evidence for distinct sodium-, dopamine-, and cocaine-dependent conformational changes in transmembrane segments 7 and 8 of the dopamine transporter. 2003 Aug 15 1
11 14612149 Probing dopamine transporter structure and function by Zn2+-site engineering. 2003 Oct 31 2
12 14612150 Interactions of cations and anions with the binding of uptake blockers to the dopamine transporter. 2003 Oct 31 2
13 11818545 Generation of an activating Zn(2+) switch in the dopamine transporter: mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle. 2002 Feb 5 3
14 11940571 The role of zinc ions in reverse transport mediated by monoamine transporters. 2002 Jun 14 1
15 12135746 Zn(2+) site engineering at the oligomeric interface of the dopamine transporter. 2002 Jul 31 4
16 11358327 Delineating structure-function relationships in the dopamine transporter from natural and engineered Zn2+ binding sites. 2001 Apr 6 3
17 11123909 Structural probing of a microdomain in the dopamine transporter by engineering of artificial Zn2+ binding sites. 2000 Dec 26 3
18 10601246 Defining proximity relationships in the tertiary structure of the dopamine transporter. Identification of a conserved glutamic acid as a third coordinate in the endogenous Zn(2+)-binding site. 1999 Dec 24 6
19 9687495 Delineation of an endogenous zinc-binding site in the human dopamine transporter. 1998 Aug 3 4