cediranib

vascular endothelial growth factor A ; Homo sapiens







80 Article(s)
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1 34715143 Cediranib, a pan-inhibitor of vascular endothelial growth factor receptors, inhibits proliferation and enhances therapeutic sensitivity in glioblastoma cells. 2021 Dec 15 1
2 30980733 Dynamics of circulating vascular endothelial growth factor-A predict benefit from antiangiogenic cediranib in metastatic or recurrent cervical cancer patients. 2019 Aug 4
3 31152080 Phase II, Multicenter, Randomized Trial of Docetaxel plus Prednisone with or Without Cediranib in Men with Chemotherapy-Naive Metastatic Castrate-Resistant Prostate Cancer. 2019 Sep 2
4 31345267 A phase I study of the PD-L1 inhibitor, durvalumab, in combination with a PARP inhibitor, olaparib, and a VEGFR1-3 inhibitor, cediranib, in recurrent women's cancers with biomarker analyses. 2019 Jul 25 1
5 29393180 Role of Radiosensitizers in Radiation Treatment of Gliomas. 2018 1
6 29925934 Circulating biomarkers during treatment in patients with advanced biliary tract cancer receiving cediranib in the UK ABC-03 trial. 2018 Jul 1
7 28933580 The role of Cediranib in ovarian cancer. 2017 Oct 1
8 29270434 High-Dose Compound Heat Map for 3D-Cultured Glioblastoma Multiforme Cells in a Micropillar and Microwell Chip Platform. 2017 2
9 26626460 Leptin, BMI, and a Metabolic Gene Expression Signature Associated with Clinical Outcome to VEGF Inhibition in Colorectal Cancer. 2016 Jan 12 2
10 26753963 Cediranib in ovarian cancer: state of the art and future perspectives. 2016 Mar 1
11 26802156 A randomized, double-blind phase II study evaluating cediranib versus cediranib and saracatinib in patients with relapsed metastatic clear-cell renal cancer (COSAK). 2016 May 1
12 26841902 A phase II study of cediranib, an oral VEGF inhibitor, in previously untreated patients with metastatic or recurrent malignant melanoma. 2016 Apr 1
13 25684635 Effects of receptor tyrosine kinase inhibitors on VEGF165 a- and VEGF165 b-stimulated gene transcription in HEK-293 cells expressing human VEGFR2. 2015 Jun 1
14 26044202 The effect of AZD2171- or sTRAIL/Apo2L-loaded polylactic-co-glycolic acid microspheres on a subcutaneous glioblastoma model. 2015 Aug 1
15 26179201 Cediranib or placebo in combination with cisplatin and gemcitabine chemotherapy for patients with advanced biliary tract cancer (ABC-03): a randomised phase 2 trial. 2015 Aug 1
16 26186911 A phase II evaluation of cediranib in the treatment of recurrent or persistent endometrial cancer: An NRG Oncology/Gynecologic Oncology Group study. 2015 Sep 2
17 26188774 A phase I trial and PK study of cediranib (AZD2171), an orally bioavailable pan-VEGFR inhibitor, in children with recurrent or refractory primary CNS tumors. 2015 Sep 2
18 26415995 Analysis of serum protein levels of angiogenic factors and their soluble receptors as markers of response to cediranib in the NCIC CTG BR.24 clinical trial. 2015 Nov 1
19 24309981 Low incidence of pseudoprogression by imaging in newly diagnosed glioblastoma patients treated with cediranib in combination with chemoradiation. 2014 Jan 2
20 24752867 Dual inhibition of the vascular endothelial growth factor pathway: a phase 1 trial evaluating bevacizumab and AZD2171 (cediranib) in patients with advanced solid tumors. 2014 Jul 15 3
21 23197081 Pharmacokinetics and tolerability of cediranib, a potent VEGF signalling inhibitor, in cancer patients with hepatic impairment. 2013 Feb 5
22 23299530 Cediranib with mFOLFOX6 vs bevacizumab with mFOLFOX6 in previously treated metastatic colorectal cancer. 2013 Feb 19 3
23 23362324 Efficacy, safety, pharmacokinetics, and biomarkers of cediranib monotherapy in advanced hepatocellular carcinoma: a phase II study. 2013 Mar 15 1
24 23651727 Intracranial meningiomas, the VEGF-A pathway, and peritumoral brain oedema. 2013 Apr 1
25 23801303 Cediranib in combination with fulvestrant in hormone-sensitive metastatic breast cancer: a randomized Phase II study. 2013 Oct 2
26 24190997 Improved tumor oxygenation and survival in glioblastoma patients who show increased blood perfusion after cediranib and chemoradiation. 2013 Nov 19 1
27 21422991 Cediranib (AZD2171) in patients with advanced hepatocellular carcinoma: a phase II North Central Cancer Treatment Group Clinical Trial. 2012 Aug 1
28 21538824 Combination testing of cediranib (AZD2171) against childhood cancer models by the pediatric preclinical testing program. 2012 Apr 4
29 21611734 Phase I results from a two-part Phase I/II study of cediranib in combination with mFOLFOX6 in Japanese patients with metastatic colorectal cancer. 2012 Aug 2
30 21828378 Cediranib in combination with mFOLFOX6 in Japanese patients with metastatic colorectal cancer: results from the randomised phase II part of a phase I/II study. 2012 Apr 2
31 21853311 Phase I study of cediranib in combination with cisplatin plus fluoropyrimidine (S-1 or capecitabine) in Japanese patients with previously untreated advanced gastric cancer. 2012 Feb 1
32 21989836 Phase I open-label study of cediranib, an oral inhibitor of VEGF signalling, in combination with the oral Src inhibitor saracatinib in patients with advanced solid tumours. 2012 Oct 2
33 22127927 Increased survival of glioblastoma patients who respond to antiangiogenic therapy with elevated blood perfusion. 2012 Jan 15 1
34 22263801 Antiangiogenic drugs in the treatment of advanced epithelial ovarian cancer. 2012 Oct 1 1
35 22285180 Cediranib monotherapy in patients with advanced renal cell carcinoma: results of a randomised phase II study. 2012 Mar 3
36 22405734 Multitargeted anti-angiogenic agents and NSCLC: clinical update and future directions. 2012 Oct 1
37 22644562 Expression of stromal genes associated with the angiogenic response are not differentiated between human tumour xenografts with divergent vascular morphologies. 2012 Dec 1
38 22830398 Cediranib: a VEGF receptor tyrosine kinase inhibitor. 2012 Jul 2
39 22831987 Cediranib in patients with malignant mesothelioma: a phase II trial of the University of Chicago Phase II Consortium. 2012 Oct 1
40 22965965 Cediranib plus FOLFOX/CAPOX versus placebo plus FOLFOX/CAPOX in patients with previously untreated metastatic colorectal cancer: a randomized, double-blind, phase III study (HORIZON II). 2012 Oct 10 3
41 23013619 Modulating antiangiogenic resistance by inhibiting the signal transducer and activator of transcription 3 pathway in glioblastoma. 2012 Sep 1
42 20607586 Cediranib in combination with various anticancer regimens: results of a phase I multi-cohort study. 2011 Dec 3
43 21120480 A two-part phase II study of cediranib in patients with advanced solid tumours: the effect of food on single-dose pharmacokinetics and an evaluation of safety, efficacy and imaging pharmacodynamics. 2011 Sep 2
44 21199795 Glioblastoma recurrence after cediranib therapy in patients: lack of "rebound" revascularization as mode of escape. 2011 Jan 1 2
45 21878941 Initial toxicity assessment of ICON6: a randomised trial of cediranib plus chemotherapy in platinum-sensitive relapsed ovarian cancer. 2011 Sep 27 3
46 21964533 Phase II study of cediranib in patients with malignant pleural mesothelioma: SWOG S0509. 2011 Nov 1
47 19674789 An open-label, Phase I study of cediranib (RECENTIN) in patients with acute myeloid leukemia. 2010 Feb 1
48 20056761 Rapid development of hypertension and proteinuria with cediranib, an oral vascular endothelial growth factor receptor inhibitor. 2010 Mar 1
49 20184547 Recent advances and future directions in the management of metastatic renal cell carcinoma. 2010 Mar 2
50 20409669 Characterisation and identification of the human N+-glucuronide metabolite of cediranib. 2010 Nov 2 3