gemcitabine

mitogen-activated protein kinase kinase 7 ; Homo sapiens







17 Article(s)
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1 35165514 Gemcitabine and XCT790, an ERRα inverse agonist, display a synergistic anticancer effect in pancreatic cancer. 2022 1
2 28060183 Gemcitabine Enhances Kras-MEK-Induced Matrix Metalloproteinase-10 Expression Via Histone Acetylation in Gemcitabine-Resistant Pancreatic Tumor-initiating Cells. 2017 Feb 2
3 28537897 MEK inhibitors cobimetinib and trametinib, regressed a gemcitabine-resistant pancreatic-cancer patient-derived orthotopic xenograft (PDOX). 2017 Jul 18 1
4 28581516 Pancreatic cancer heterogeneity and response to Mek inhibition. 2017 Oct 5 1
5 25376606 Modeling targeted inhibition of MEK and PI3 kinase in human pancreatic cancer. 2015 Jan 1
6 25946136 Let-7 Sensitizes KRAS Mutant Tumor Cells to Chemotherapy. 2015 1
7 26228206 The MEK1/2 Inhibitor Pimasertib Enhances Gemcitabine Efficacy in Pancreatic Cancer Models by Altering Ribonucleotide Reductase Subunit-1 (RRM1). 2015 Dec 15 1
8 24819705 HS-104, a PI3K inhibitor, enhances the anticancer efficacy of gemcitabine in pancreatic cancer. 2014 Jul 1
9 24966685 Gemcitabine resistance in breast cancer cells regulated by PI3K/AKT-mediated cellular proliferation exerts negative feedback via the MEK/MAPK and mTOR pathways. 2014 1
10 23091117 Sequence dependence of MEK inhibitor AZD6244 combined with gemcitabine for the treatment of biliary cancer. 2013 Jan 1 2
11 23255896 Sorafenib combined with gemcitabine in EGFR-TKI-resistant human lung cancer cells. 2013 Jan 1
12 23320839 MEK inhibition induced downregulation of MRP1 and MRP3 expression in experimental hepatocellular carcinoma. 2013 Jan 15 2
13 22797388 New tools and novel approaches in treating locally advanced pancreatic adenocarcinoma. 2012 Jul 10 1
14 22110196 Mechanisms underlying gemcitabine resistance in pancreatic cancer and sensitisation by the iMiD™ lenalidomide. 2011 Nov 3
15 18049840 Pancreatic cancer cell genetics and signaling response to treatment correlate with efficacy of gemcitabine-based molecular targeting strategies. 2008 Feb 1
16 18813828 The growth inhibition of hepatocellular and cholangiocellular carcinoma cells by gemcitabine and the roles of extracellular signal-regulated and checkpoint kinases. 2008 Oct 1
17 16307741 Activation of c-Jun NH2-terminal kinase is required for gemcitabine's cytotoxic effect in human lung cancer H1299 cells. 2005 Dec 5 1