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34512368 | Targeting Autophagy with Natural Compounds in Cancer: A Renewed Perspective from Molecular Mechanisms to Targeted Therapy. | 2021 |
1 |
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30383888 | Phase 1 study of the combination of vemurafenib, carboplatin, and paclitaxel in patients with BRAF-mutated melanoma and other advanced malignancies. | 2019 Feb 1 |
1 |
| 3 |
31334335 | FoxM1 Induced Paclitaxel Resistance via Activation of the FoxM1/PHB1/RAF-MEK-ERK Pathway and Enhancement of the ABCA2 Transporter. | 2019 Sep 27 |
2 |
| 4 |
29374144 | Dual PI3K/mTOR inhibitor BEZ235 as a promising therapeutic strategy against paclitaxel-resistant gastric cancer via targeting PI3K/Akt/mTOR pathway. | 2018 Jan 26 |
1 |
| 5 |
29435178 | Inhibition of the MEK/ERK pathway augments nab-paclitaxel-based chemotherapy effects in preclinical models of pancreatic cancer. | 2018 Jan 12 |
1 |
| 6 |
29844129 | Phase Ib Study of Binimetinib with Paclitaxel in Patients with Platinum-Resistant Ovarian Cancer: Final Results, Potential Biomarkers, and Extreme Responders. | 2018 Nov 15 |
1 |
| 7 |
30094097 | Trametinib suppresses chemotherapy-induced cold and mechanical allodynia via inhibition of extracellular-regulated protein kinase 1/2 activation. | 2018 |
1 |
| 8 |
27811011 | MENA Confers Resistance to Paclitaxel in Triple-Negative Breast Cancer. | 2017 Jan |
1 |
| 9 |
28380350 | Tumor-Associated Macrophages Suppress the Cytotoxic Activity of Antimitotic Agents. | 2017 Apr 4 |
1 |
| 10 |
28581516 | Pancreatic cancer heterogeneity and response to Mek inhibition. | 2017 Oct 5 |
2 |
| 11 |
25542057 | PACMEL: a phase 1 dose escalation trial of trametinib (GSK1120212) in combination with paclitaxel. | 2015 Feb |
1 |
| 12 |
25946136 | Let-7 Sensitizes KRAS Mutant Tumor Cells to Chemotherapy. | 2015 |
1 |
| 13 |
24173825 | Caffeine inhibits paclitaxel‑induced apoptosis in colorectal cancer cells through the upregulation of Mcl‑1 levels. | 2014 Jan |
3 |
| 14 |
22005063 | Paclitaxel induced B7-H1 expression in cancer cells via the MAPK pathway. | 2011 Oct |
1 |
| 15 |
24212635 | Ras Isoprenylation and pAkt Inhibition by Zoledronic Acid and Fluvastatin Enhances Paclitaxel Activity in T24 Bladder Cancer Cells. | 2011 Feb 14 |
1 |
| 16 |
19331159 | Enhancement of paclitaxel-induced apoptosis by inhibition of mitogen-activated protein kinase pathway in colon cancer cells. | 2009 Jan |
2 |
| 17 |
19521235 | Inhibition of MEK sensitizes paclitaxel-induced apoptosis of human colorectal cancer cells by downregulation of GRP78. | 2009 Aug |
4 |
| 18 |
15805287 | Enhancement of the therapeutic efficacy of taxol by the mitogen-activated protein kinase kinase inhibitor CI-1040 in nude mice bearing human heterotransplants. | 2005 Apr 1 |
5 |
| 19 |
16101130 | Biomarkers of anticancer activity of R115777 (Tipifarnib, Zarnestra) in human breast cancer models in vitro. | 2005 Sep-Oct |
1 |
| 20 |
14742319 | Id-1-induced Raf/MEK pathway activation is essential for its protective role against taxol-induced apoptosis in nasopharyngeal carcinoma cells. | 2004 Jun |
4 |
| 21 |
15001534 | Phosphorylation of FADD is critical for sensitivity to anticancer drug-induced apoptosis. | 2004 Jul |
2 |
| 22 |
12838322 | Roles of the PI-3K and MEK pathways in Ras-mediated chemoresistance in breast cancer cells. | 2003 Jul 7 |
1 |
| 23 |
14583493 | Proteomic profiling drug-induced apoptosis in non-small cell lung carcinoma: identification of RS/DJ-1 and RhoGDIalpha. | 2003 Oct 15 |
7 |
| 24 |
12087097 | Inhibition of phosphorylation of BAD and Raf-1 by Akt sensitizes human ovarian cancer cells to paclitaxel. | 2002 Sep 6 |
1 |
| 25 |
12114408 | Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of taxol and mitogen-activated protein kinase kinase inhibition. | 2002 Jul |
5 |
| 26 |
12181443 | Akt activation induced by lysophosphatidic acid and sphingosine-1-phosphate requires both mitogen-activated protein kinase kinase and p38 mitogen-activated protein kinase and is cell-line specific. | 2002 Sep |
1 |
| 27 |
11278851 | Paclitaxel induces prolonged activation of the Ras/MEK/ERK pathway independently of activating the programmed cell death machinery. | 2001 Jun 1 |
1 |
| 28 |
11408609 | Sequence-dependent potentiation of paclitaxel-mediated apoptosis in human leukemia cells by inhibitors of the mitogen-activated protein kinase kinase/mitogen-activated protein kinase pathway. | 2001 Jul |
2 |
| 29 |
10737257 | 12-O-tetradecanoyl phorbol 13-acetate, protein kinase C (PKC) activator, protects human leukemia HL-60 cells from taxol-induced apoptosis: possible role for extracellular signal-regulated kinase. | 2000 Feb |
5 |
| 30 |
11016645 | Taxol mediates serine phosphorylation of the 66-kDa Shc isoform. | 2000 Sep 15 |
1 |
| 31 |
11038347 | MEK inhibition enhances paclitaxel-induced tumor apoptosis. | 2000 Dec 15 |
3 |
| 32 |
9783732 | Effect of bryostatin 1 on taxol-induced apoptosis and cytotoxicity in human leukemia cells (U937). | 1998 Sep 1 |
1 |