Nigericin

NLR family pyrin domain containing 3 ; Homo sapiens







52 Article(s)
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1 35062292 Influenza A Virus Infection Activates NLRP3 Inflammasome through Trans-Golgi Network Dispersion. 2022 Jan 5 1
2 35246004 Emodin relieves the inflammation and pyroptosis of lipopolysaccharide-treated 1321N1 cells by regulating methyltransferase-like 3 -mediated NLR family pyrin domain containing 3 expression. 2022 Mar 2
3 35406727 Inflammatory Caspase Activity Mediates HMGB1 Release and Differentiation in Myoblasts Affected by Peripheral Arterial Disease. 2022 Mar 30 1
4 35440074 Dehydroepiandrosterone exacerbates nigericin-induced abnormal autophagy and pyroptosis via GPER activation in LPS-primed macrophages. 2022 Apr 19 1
5 33231721 Aquaporin-3 is involved in NLRP3-inflammasome activation contributing to the setting of inflammatory response. 2021 Mar 1
6 33573688 Icariside I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity. 2021 Feb 11 1
7 33683342 Heterogeneous NLRP3 inflammasome signature in circulating myeloid cells as a biomarker of COVID-19 severity. 2021 Mar 9 1
8 33830232 1'-Acetoxychavicol acetate inhibits NLRP3-dependent inflammasome activation via mitochondrial ROS suppression. 2021 Jun 18 1
9 33835494 NLR family pyrin domain containing 3 (NLRP3) and caspase 1 (CASP1) modulation by intracellular Cl- concentration. 2021 Aug 2
10 33855019 Compliant Substrates Enhance Macrophage Cytokine Release and NLRP3 Inflammasome Formation During Their Pro-Inflammatory Response. 2021 1
11 33909257 Bavachin enhances NLRP3 inflammasome activation induced by ATP or nigericin and causes idiosyncratic hepatotoxicity. 2021 Aug 3
12 34350239 Ulinastatin inhibits NLRP3-induced apoptosis in a PD cell model. 2021 Jun 3
13 34403206 IKKβ is required for the formation of the NLRP3 inflammasome. 2021 Oct 5 5
14 34447480 IL-22 alleviates the fibrosis of hepatic stellate cells via the inactivation of NLRP3 inflammasome signaling. 2021 Oct 2
15 31895698 Bruton tyrosine kinase deficiency augments NLRP3 inflammasome activation and causes IL-1β-mediated colitis. 2020 Apr 1 2
16 32230726 Helicobacter pylori Avoids the Critical Activation of NLRP3 Inflammasome-Mediated Production of Oncogenic Mature IL-1β in Human Immune Cells. 2020 Mar 27 1
17 32410829 Tendril extract of Cucurbita moschata suppresses NLRP3 inflammasome activation in murine macrophages and human trophoblast cells. 2020 1
18 32445196 Hallmarks of NLRP3 inflammasome activation are observed in organotypic hippocampal slice culture. 2020 Sep 1
19 33092247 Rab GTPase Mediating Regulation of NALP3 in Colorectal Cancer. 2020 Oct 20 1
20 33101286 Priming Is Dispensable for NLRP3 Inflammasome Activation in Human Monocytes In Vitro. 2020 1
21 33182075 FUN14 domain-containing 1-mediated mitophagy suppresses interleukin-1β production in macrophages. 2020 Nov 2
22 33613529 Therapeutic Potential of Pharmacological Targeting NLRP3 Inflammasome Complex in Cancer. 2020 3
23 30735689 Optimized protocols for studying the NLRP3 inflammasome and assessment of potential targets of CP-453,773 in undifferentiated THP1 cells. 2019 Apr 3
24 30804327 The classical NLRP3 inflammasome controls FADD unconventional secretion through microvesicle shedding. 2019 Feb 25 1
25 30807742 The role of lysosomal cysteine cathepsins in NLRP3 inflammasome activation. 2019 Jul 30 1
26 31086288 Forskolin attenuates the NLRP3 inflammasome activation and IL-1β secretion in human macrophages. 2019 Dec 2
27 31189953 Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome. 2019 Jun 1
28 31214205 Evaluation of Canonical Inflammasome Activation in Human Monocytes by Imaging Flow Cytometry. 2019 1
29 31632394 Nigericin Promotes NLRP3-Independent Bacterial Killing in Macrophages. 2019 2
30 31677073 Carbamazepine promotes specific stimuli-induced NLRP3 inflammasome activation and causes idiosyncratic liver injury in mice. 2019 Dec 1
31 29145789 Helicobacter pylori controls NLRP3 expression by regulating hsa-miR-223-3p and IL-10 in cultured and primary human immune cells. 2018 Jan 1
32 29479354 Withaferin A Associated Differential Regulation of Inflammatory Cytokines. 2018 1
33 30513737 Study of Potential Anti-Inflammatory Effects of Red Wine Extract and Resveratrol through a Modulation of Interleukin-1-Beta in Macrophages. 2018 Dec 1 1
34 30555323 Pathophysiology of NSAID-Associated Intestinal Lesions in the Rat: Luminal Bacteria and Mucosal Inflammation as Targets for Prevention. 2018 1
35 28216434 Human NACHT, LRR, and PYD domain-containing protein 3 (NLRP3) inflammasome activity is regulated by and potentially targetable through Bruton tyrosine kinase. 2017 Oct 1
36 28729291 Stimulator of IFN genes-mediated DNA-sensing pathway is suppressed by NLRP3 agonists and regulated by mitofusin 1 and TBC1D15, mitochondrial dynamics mediators. 2017 Nov 1
37 28787755 A rapid administration of GW4064 inhibits the NLRP3 inflammasome activation independent of farnesoid X receptor agonism. 2017 Sep 1
38 29263464 [Effect of high glucose-based peritoneal dialysis fluids on NLRP3-IL-1β in human peritoneal mesothelial cells]. 2017 Dec 18 1
39 29911779 [Inhibitory effect and mechanism of deoxyschizandrin on NLRP3 inflammasome]. 2017 Jan 2
40 26825654 The role of Resveratrol-induced mitophagy/autophagy in peritoneal mesothelial cells inflammatory injury via NLRP3 inflammasome activation triggered by mitochondrial ROS. 2016 Feb 1 1
41 27431477 F-actin dampens NLRP3 inflammasome activity via Flightless-I and LRRFIP2. 2016 Jul 19 1
42 28516117 Reconstruction of the Mouse Inflammasome System in HEK293T Cells. 2016 Nov 5 1
43 25770182 Carbon monoxide negatively regulates NLRP3 inflammasome activation in macrophages. 2015 May 15 1
44 26412089 Chronic TLR Stimulation Controls NLRP3 Inflammasome Activation through IL-10 Mediated Regulation of NLRP3 Expression and Caspase-8 Activation. 2015 Sep 28 1
45 26546608 Intracellular ATP Decrease Mediates NLRP3 Inflammasome Activation upon Nigericin and Crystal Stimulation. 2015 Dec 15 2
46 26611636 Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion. 2015 Dec 1
47 25054228 Aberrant expression of interleukin-1β and inflammasome activation in human malignant gliomas. 2014 1
48 25225670 Cytosolic double-stranded RNA activates the NLRP3 inflammasome via MAVS-induced membrane permeabilization and K+ efflux. 2014 Oct 15 1
49 23253918 Regulation of interleukin 1α secretion by inflammasomes. 2013 Apr 1
50 23809161 K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter. 2013 Jun 27 1