Silicon Dioxide

NLR family pyrin domain containing 3 ; Homo sapiens







30 Article(s)
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1 34766707 Microcrystalline silica particles induce inflammatory response via pyroptosis in primary human respiratory epithelial cells. 2022 Mar 3
2 34864055 Extracellular cathepsin Z signals through the α5 integrin and augments NLRP3 inflammasome activation. 2022 Jan 1
3 34969174 The interplay between ASMase signaling pathway and NLRP3 in the epithelial to mesenchymal transition of HBE cells induced by silica. 2022 Jun 6
4 35219847 Silica nanoparticles induce pyroptosis and cardiac hypertrophy via ROS/NLRP3/Caspase-1 pathway. 2022 Mar 1
5 33053467 Amorphous silica nanoparticles induce inflammation via activation of NLRP3 inflammasome and HMGB1/TLR4/MYD88/NF-kb signaling pathway in HUVEC cells. 2021 Feb 15 1
6 34336106 The Ameliorative Effects of Arctiin and Arctigenin on the Oxidative Injury of Lung Induced by Silica via TLR-4/NLRP3/TGF-β Signaling Pathway. 2021 2
7 33012733 Exogenous Clara cell protein 16 attenuates silica particles-induced inflammation in THP-1 macrophages by down-regulating NF-κB and caspase-1 activation. 2020 1
8 33144845 Molecularly Distinct NLRP3 Inducers Mediate Diverse Ratios of Interleukin-1β and Interleukin-18 from Human Monocytes. 2020 1
9 30807742 The role of lysosomal cysteine cathepsins in NLRP3 inflammasome activation. 2019 Jul 30 1
10 30847537 Carbon nanotubes and crystalline silica stimulate robust ROS production, inflammasome activation, and IL-1β secretion in macrophages to induce myofibroblast transformation. 2019 Apr 1
11 29258746 NLRP3 inflammasome inhibition attenuates silica-induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells. 2018 Jan 15 7
12 28177948 Silicosis and autoimmunity. 2017 Apr 3
13 28968864 ATM-activated autotaxin (ATX) propagates inflammation and DNA damage in lung epithelial cells: a new mode of action for silica-induced DNA damage? 2017 Dec 7 1
14 29113588 Silica nanoparticles induce NLRP3 inflammasome activation in human primary immune cells. 2017 Nov 1
15 29403480 Volcanic Ash Activates the NLRP3 Inflammasome in Murine and Human Macrophages. 2017 2
16 25654762 The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine. 2015 Feb 5 2
17 26114647 PKC/ROS-Mediated NLRP3 Inflammasome Activation Is Attenuated by Leishmania Zinc-Metalloprotease during Infection. 2015 1
18 25445147 Activation of NLRP3 inflammasome by crystalline structures via cell surface contact. 2014 Dec 2 1
19 25486008 Interferon-tau attenuates uptake of nanoparticles and secretion of interleukin-1β in macrophages. 2014 1
20 23402370 Silica induces NLRP3 inflammasome activation in human lung epithelial cells. 2013 Feb 12 2
21 22534002 Silicosis. 2012 May 26 1
22 22924492 Processing pathway dependence of amorphous silica nanoparticle toxicity: colloidal vs pyrolytic. 2012 Sep 26 1
23 21596183 [Pathophysiological mechanisms underlying cryopyrin-associated periodic syndromes: genetic and molecular basis and the inflammasome]. 2011 Jan 2
24 21936977 [Danger signals and inflammasomes in autoinflammatory and autoimmune diseases]. 2011 Sep 19 1
25 20561679 The effect of surface modification of amorphous silica particles on NLRP3 inflammasome mediated IL-1beta production, ROS production and endosomal rupture. 2010 Sep 2
26 21126439 [Progress in research on role of inflammasome Nalp3 in silica dusts induced body injuries]. 2010 Oct 1
27 19542372 Cutting edge: TNF-alpha mediates sensitization to ATP and silica via the NLRP3 inflammasome in the absence of microbial stimulation. 2009 Jul 15 1
28 19633559 Innate immunity and inflammation in systemic sclerosis. 2009 Nov 1
29 18577586 The Nalp3 inflammasome is essential for the development of silicosis. 2008 Jul 1 4
30 18604214 Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. 2008 Aug 2