| 1 |
33707655 | Development of a drug screening system using three-dimensional cardiac tissues containing multiple cell types. | 2021 Mar 11 |
1 |
| 2 |
33986332 | A predictive in vitro risk assessment platform for pro-arrhythmic toxicity using human 3D cardiac microtissues. | 2021 May 13 |
1 |
| 3 |
34572598 | The Effect of a Synthetic Estrogen, Ethinylestradiol, on the hERG Block by E-4031. | 2021 Sep 20 |
6 |
| 4 |
34681161 | Induced Pluripotent Stem Cell-Derived Cardiomyocytes with SCN5A R1623Q Mutation Associated with Severe Long QT Syndrome in Fetuses and Neonates Recapitulates Pathophysiological Phenotypes. | 2021 Oct 18 |
1 |
| 5 |
32321643 | Serine mutation of a conserved threonine in the hERG K+ channel S6-pore region leads to loss-of-function through trafficking impairment. | 2020 Jun 11 |
1 |
| 6 |
30800649 | Aggregation-Induced Emission: Lighting Up hERG Potassium Channel. | 2019 |
1 |
| 7 |
30807184 | Intracellular Mechanism of Rosuvastatin-Induced Decrease in Mature hERG Protein Expression on Membrane. | 2019 Apr 1 |
1 |
| 8 |
31017964 | Hypoxia induced hERG trafficking defect linked to cell cycle arrest in SH-SY5Y cells. | 2019 |
2 |
| 9 |
31520926 | Discovery of a potent p38α/MAPK14 kinase inhibitor: Synthesis, in vitro/in vivo biological evaluation, and docking studies. | 2019 Dec 1 |
1 |
| 10 |
29555184 | Proarrhythmia risk prediction using human induced pluripotent stem cell-derived cardiomyocytes. | 2018 Apr |
1 |
| 11 |
28448053 | Automated Contraction Analysis of Human Engineered Heart Tissue for Cardiac Drug Safety Screening. | 2017 Apr 15 |
1 |
| 12 |
27199074 | Pharmacological rescue of hERG currents carried out by G604S and wide type hERG co-expression. | 2016 Sep |
6 |
| 13 |
27282640 | Multi-parametric assessment of cardiomyocyte excitation-contraction coupling using impedance and field potential recording: A tool for cardiac safety assessment. | 2016 Sep-Oct |
1 |
| 14 |
27704082 | Evaluation of drug-mediated arrhythmic changes in spontaneous beating cardiomyocytes by AFM. | 2016 Nov 21 |
1 |
| 15 |
25219538 | Human stem cell-derived cardiomyocytes detect drug-mediated changes in action potentials and ion currents. | 2014 Nov-Dec |
1 |
| 16 |
23160842 | hERG drug response measured in droplet bilayers. | 2013 Apr |
1 |
| 17 |
21919210 | Understanding of molecular substructures that contribute to hERG K+ channel blockade: synthesis and biological evaluation of E-4031 analogues. | 2012 Jan 2 |
1 |
| 18 |
22198052 | A novel method of selecting human embryonic stem cell-derived cardiomyocyte clusters for assessment of potential to influence QT interval. | 2012 Mar |
1 |
| 19 |
22498908 | Development of recombinant cell line co-expressing mutated Nav1.5, Kir2.1, and hERG for the safety assay of drug candidates. | 2012 Jul |
1 |
| 20 |
22936309 | hERG ion channel pharmacology: cell membrane liposomes in porous-supported lipid bilayers compared with whole-cell patch-clamping. | 2012 Nov |
1 |
| 21 |
23020479 | Chaotic dynamics in cardiac aggregates induced by potassium channel block. | 2012 Sep |
1 |
| 22 |
21205913 | BeKm-1, a peptide inhibitor of human ether-a-go-go-related gene potassium currents, prolongs QTc intervals in isolated rabbit heart. | 2011 Apr |
2 |
| 23 |
21490315 | Trafficking-deficient hERG K⁺ channels linked to long QT syndrome are regulated by a microtubule-dependent quality control compartment in the ER. | 2011 Jul |
3 |
| 24 |
22028871 | Human engineered heart tissue as a versatile tool in basic research and preclinical toxicology. | 2011 |
1 |
| 25 |
19805508 | Pharmacological removal of human ether-à-go-go-related gene potassium channel inactivation by 3-nitro-N-(4-phenoxyphenyl) benzamide (ICA-105574). | 2010 Jan |
4 |
| 26 |
20153443 | The action potential and comparative pharmacology of stem cell-derived human cardiomyocytes. | 2010 May-Jun |
1 |
| 27 |
20188738 | Modulation of cardiac ERG1 K(+) channels by cGMP signaling. | 2010 Jul |
1 |
| 28 |
20407085 | Human embryonic stem cell-derived cardiomyocytes: demonstration of a portion of cardiac cells with fairly mature electrical phenotype. | 2010 Apr |
1 |
| 29 |
19426697 | Analogs of MK-499 are differentially affected by a mutation in the S6 domain of the hERG K+ channel. | 2009 May 15 |
1 |
| 30 |
18497958 | Pharmacological separation of hEAG and hERG K+ channel function in the human mammary carcinoma cell line MCF-7. | 2008 Jun |
2 |
| 31 |
18724381 | Pharmacology of the short QT syndrome N588K-hERG K+ channel mutation: differential impact on selected class I and class III antiarrhythmic drugs. | 2008 Nov |
3 |
| 32 |
16474003 | Molecular determinants of HERG channel block. | 2006 May |
1 |
| 33 |
12634931 | HERG K(+) currents in human prolactin-secreting adenoma cells. | 2003 Feb |
1 |
| 34 |
12958021 | ERG K+ currents regulate pacemaker activity in ICC. | 2003 Dec |
1 |
| 35 |
10804231 | Do glia have heart? Expression and functional role for ether-a-go-go currents in hippocampal astrocytes. | 2000 May 15 |
1 |