Flavonoids

ATP binding cassette subfamily G member 2 (Junior blood group) ; Homo sapiens







39 Article(s)
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1 34606270 Flavonoid Monomers as Potent, Nontoxic, and Selective Modulators of the Breast Cancer Resistance Protein (ABCG2). 2021 Oct 14 3
2 32357395 Quercetin Is a Flavonoid Breast Cancer Resistance Protein Inhibitor with an Impact on the Oral Pharmacokinetics of Sulfasalazine in Rats. 2020 Apr 26 1
3 32722234 Overcoming Multidrug Resistance: Flavonoid and Terpenoid Nitrogen-Containing Derivatives as ABC Transporter Modulators. 2020 Jul 24 2
4 29436891 Identification of UGTs and BCRP as potential pharmacokinetic determinants of the natural flavonoid alpinetin. 2019 Mar 1
5 31465686 Triazole Bridged Flavonoid Dimers as Potent, Nontoxic, and Highly Selective Breast Cancer Resistance Protein (BCRP/ABCG2) Inhibitors. 2019 Sep 26 4
6 31493543 Evaluation of inhibitory effects of flavonoids on breast cancer resistance protein (BCRP): From library screening to biological evaluation to structure-activity relationship. 2019 Dec 10
7 31501221 Direct Measurement of Kinetic Parameters of ABCG2-Dependent Transport of Natural Flavonoids Using a Fluorogenic Substrate. 2019 Nov 4
8 28043125 Inhibition of Breast Cancer Resistance Protein and Multidrug Resistance Associated Protein 2 by Natural Compounds and Their Derivatives. 2017 Jan 3 1
9 28632894 Flavonoids as modulators of metabolic enzymes and drug transporters. 2017 Jun 1
10 26467069 Association of flavonoid-rich foods and statins in the management of hypercholesterolemia: a dangerous or helpful combination? 2015 1
11 24735762 Karanjin interferes with ABCB1, ABCC1, and ABCG2. 2014 1
12 23192864 Determination of functional ABCG2 activity and assessment of drug-ABCG2 interactions in dairy animals using a novel MDCKII in vitro model. 2013 Feb 1
13 22071170 UDP-glucuronosyltransferase (UGT) 1A9-overexpressing HeLa cells is an appropriate tool to delineate the kinetic interplay between breast cancer resistance protein (BRCP) and UGT and to rapidly identify the glucuronide substrates of BCRP. 2012 Feb 1
14 22830339 (Iso)flav(an)ones, chalcones, catechins, and theaflavins as anticarcinogens: mechanisms, anti-multidrug resistance and QSAR studies. 2012 3
15 23369170 Versatile inhibitory effects of the flavonoid-derived PI3K/Akt inhibitor, LY294002, on ATP-binding cassette transporters that characterize stem cells. 2012 Oct 13 1
16 21118093 The challenge of exploiting ABCG2 in the clinic. 2011 Apr 3
17 21275386 Flavonoids from eight tropical plant species that inhibit the multidrug resistance transporter ABCG2. 2011 Feb 25 2
18 21354800 Structure-activity relationships of flavonoids as inhibitors of breast cancer resistance protein (BCRP). 2011 Mar 15 6
19 21728961 Targeting the multidrug ABCG2 transporter with flavonoidic inhibitors: in vitro optimization and in vivo validation. 2011 1
20 20112299 The effect of co-administered flavonoids on the metabolism of hesperetin and the disposition of its metabolites in Caco-2 cell monolayers. 2010 Jun 2
21 20457140 Chrysin blocks topotecan-induced apoptosis in Caco-2 cells in spite of inhibition of ABC-transporters. 2010 Aug 15 1
22 19111841 Functions of the breast cancer resistance protein (BCRP/ABCG2) in chemotherapy. 2009 Jan 31 1
23 19135106 QSAR analysis and molecular modeling of ABCG2-specific inhibitors. 2009 Jan 31 1
24 19501160 Breast cancer resistance protein (BCRP/ABCG2): new inhibitors and QSAR studies by a 3D linear solvation energy approach. 2009 Aug 12 1
25 17093006 Effects of the flavonoid chrysin on nitrofurantoin pharmacokinetics in rats: potential involvement of ABCG2. 2007 Feb 4
26 17345086 Flavonoids inhibit breast cancer resistance protein-mediated drug resistance: transporter specificity and structure-activity relationship. 2007 Nov 5
27 17407835 Extending the good diet, good health paradigm: modulation of breast cancer resistance protein (BCRP) by flavonoids. 2007 Apr 2
28 18089721 New inhibitors of ABCG2 identified by high-throughput screening. 2007 Dec 1
29 16303243 Functional SNPs of the breast cancer resistance protein-therapeutic effects and inhibitor development. 2006 Mar 8 2
30 16490770 A high-throughput cell-based assay for inhibitors of ABCG2 activity. 2006 Mar 1
31 15608138 Flavonoids chrysin and benzoflavone, potent breast cancer resistance protein inhibitors, have no significant effect on topotecan pharmacokinetics in rats or mdr1a/1b (-/-) mice. 2005 Mar 2
32 15930306 Flavonoid structure-activity studies identify 6-prenylchrysin and tectochrysin as potent and specific inhibitors of breast cancer resistance protein ABCG2. 2005 Jun 1 2
33 15979586 Structure activity relationships and quantitative structure activity relationships for the flavonoid-mediated inhibition of breast cancer resistance protein. 2005 Aug 15 12
34 16081670 Flavonoids as a novel class of human organic anion-transporting polypeptide OATP1B1 (OATP-C) modulators. 2005 Nov 1
35 16108826 Breast cancer resistance protein: molecular target for anticancer drug resistance and pharmacokinetics/pharmacodynamics. 2005 Aug 1
36 15102949 Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport. 2004 May 3
37 15205350 Phytoestrogens/flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance. 2004 Jun 15 11
38 15255290 Transport of SN-38 by the wild type of human ABC transporter ABCG2 and its inhibition by quercetin, a natural flavonoid. 2004 Apr 3
39 15290869 Combined effects of multiple flavonoids on breast cancer resistance protein (ABCG2)-mediated transport. 2004 Jul 15