pirfenidone

transforming growth factor, beta 1 ; Mus musculus







15 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35504143 Pirfenidone mitigates TGF-β1-mediated fibrosis in an idiopathic inflammatory myositis-associated interstitial lung disease model. 2022 Jun 4
2 34327818 Pirfenidone modulates macrophage polarization and ameliorates radiation-induced lung fibrosis by inhibiting the TGF-β1/Smad3 pathway. 2021 Sep 2
3 32448163 Pirfenidone alleviates pulmonary fibrosis in vitro and in vivo through regulating Wnt/GSK-3β/β-catenin and TGF-β1/Smad2/3 signaling pathways. 2020 May 24 1
4 32714072 TGFβ1 induces bone formation from BMP9-activated Bone Mesenchymal Stem Cells, with possible involvement of non-canonical pathways. 2020 1
5 29552620 Activation of Myofibroblast TRPA1 by Steroids and Pirfenidone Ameliorates Fibrosis in Experimental Crohn's Disease. 2018 Mar 1
6 29621494 Pirfenidone inhibits cryoablation induced local macrophage infiltration along with its associated TGFb1 expression and serum cytokine level in a mouse model. 2018 Jun 1
7 29879429 Increase of SOX9 promotes hepatic ischemia/reperfusion (IR) injury by activating TGF-β1. 2018 Sep 3 1
8 30016220 Antifibrotic Agent Pirfenidone Protects against Development of Radiation-Induced Pulmonary Fibrosis in a Murine Model. 2018 Oct 1
9 28254742 Pirfenidone ameliorates murine chronic GVHD through inhibition of macrophage infiltration and TGF-β production. 2017 May 4 1
10 26589264 XL413, a cell division cycle 7 kinase inhibitor enhanced the anti-fibrotic effect of pirfenidone on TGF-β1-stimulated C3H10T1/2 cells via Smad2/4. 2015 Dec 10 5
11 18598692 Antifibrotic action of pirfenidone and prednisolone: different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis. 2008 Aug 20 2
12 16770778 Long-term administration of pirfenidone improves cardiac function in mdx mice. 2006 Sep 2
13 16210133 Pirfenidone inhibits obliterative airway disease in mouse tracheal allografts. 2005 Oct 2
14 12098599 Pirfenidone suppresses tumor necrosis factor-alpha, enhances interleukin-10 and protects mice from endotoxic shock. 2002 Jun 20 1
15 11525779 Modulation of airway remodeling-associated mediators by the antifibrotic compound, pirfenidone, and the matrix metalloproteinase inhibitor, batimastat, during acute lung injury in mice. 2001 Aug 24 1