Phorbol Esters

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protein kinase D1 ; Homo sapiens







27 Article(s)
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#Total Relationships
1 25578563 PKD1 is downregulated in non-small cell lung cancer and mediates the feedback inhibition of mTORC1-S6K1 axis in response to phorbol ester. 2015 Mar 1
2 22228765 Protein kinase D regulates RhoA activity via rhotekin phosphorylation. 2012 Mar 16 2
3 21595773 Phorbol 12,13 dibutyrate behaves in a tumor-inhibitory manner in esophageal adenocarcinoma cell lines. 2011 Nov 1
4 21642422 Receptor-independent protein kinase C alpha (PKCalpha) signaling by calpain-generated free catalytic domains induces HDAC5 nuclear export and regulates cardiac transcription. 2011 Jul 29 1
5 21665893 A protein kinase C/protein kinase D pathway protects LNCaP prostate cancer cells from phorbol ester-induced apoptosis by promoting ERK1/2 and NF-{kappa}B activities. 2011 Aug 1
6 20832999 The potential use of protein kinase D inhibitors for prevention/treatment of epidermal tumors. 2010 Oct 1
7 18483269 Protein kinase D3 (PKD3) contributes to prostate cancer cell growth and survival through a PKCepsilon/PKD3 pathway downstream of Akt and ERK 1/2. 2008 May 15 2
8 15590638 Dual phospholipase C/diacylglycerol requirement for protein kinase D1 activation in lymphocytes. 2005 Feb 18 1
9 16111639 Protein kinase D1 and the beta 1 integrin cytoplasmic domain control beta 1 integrin function via regulation of Rap1 activation. 2005 Aug 2
10 16313517 Opposing effects of phorbol-12-myristate-13-acetate, an activator of protein kinase C, on the signaling of structurally related human dopamine D1 and D5 receptors. 2005 Dec 1
11 15190080 G protein-coupled receptor-mediated phosphorylation of the activation loop of protein kinase D: dependence on plasma membrane translocation and protein kinase Cepsilon. 2004 Aug 13 1
12 14645664 Ligand structure-activity requirements and phospholipid dependence for the binding of phorbol esters to protein kinase D. 2003 Dec 5
13 10867018 Regulation of protein kinase D by multisite phosphorylation. Identification of phosphorylation sites by mass spectrometry and characterization by site-directed mutagenesis. 2000 Jun 30 4
14 11008129 Effects of resveratrol on the autophosphorylation of phorbol ester-responsive protein kinases: inhibition of protein kinase D but not protein kinase C isozyme autophosphorylation. 2000 Nov 1 2
15 9973202 Protein kinase D in small cell lung cancer cells: rapid activation through protein kinase C. 1999 Feb 1 1
16 10092600 Protein kinase C mu is negatively regulated by 14-3-3 signal transduction proteins. 1999 Apr 2 3
17 10413094 Protein kinase D activation by deletion of its cysteine-rich motifs. 1999 Jul 2 1
18 10473617 Characterization of serine 916 as an in vivo autophosphorylation site for protein kinase D/Protein kinase Cmu. 1999 Sep 10 2
19 10498194 Synthesis and phorbol ester-binding studies of the individual cysteine-rich motifs of protein kinase D. 1999 Sep 6 1
20 9468299 Differential effects of suramin on protein kinase C isoenzymes. A novel tool for discriminating protein kinase C activities. 1998 Jan 9 1
21 9804164 Dissimilar phorbol ester binding properties of the individual cysteine-rich motifs of protein kinase D. 1998 Oct 16 3
22 9191157 Protein kinase D: a novel target for diacylglycerol and phorbol esters. 1997 May 1
23 8601451 In vitro activation and substrates of recombinant, baculovirus expressed human protein kinase C mu. 1996 Mar 4 1
24 7851400 Characterization of activators and inhibitors of protein kinase C mu. 1995 Jan 15 1
25 8538623 Protein kinase D (PKD): a novel target for diacylglycerol and phorbol esters. 1995 Dec 7
26 8078925 Molecular cloning and characterization of protein kinase D: a target for diacylglycerol and phorbol esters with a distinctive catalytic domain. 1994 Aug 30 5
27 8119958 PKCu is a novel, atypical member of the protein kinase C family. 1994 Feb 25 2