Tyrosine

Casitas B-lineage lymphoma ; Mus musculus







78 Article(s)
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1 32434911 CD5 signalosome coordinates antagonist TCR signals to control the generation of Treg cells induced by foreign antigens. 2020 Jun 9 1
2 33093168 Tumor Fibroblast-Derived FGF2 Regulates Expression of SPRY1 in Esophageal Tumor-Infiltrating T Cells and Plays a Role in T-cell Exhaustion. 2020 Dec 15 1
3 31282857 Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells. 2019 Jul 8 1
4 24470255 Loss of Cbl-PI3K interaction enhances osteoclast survival due to p21-Ras mediated PI3K activation independent of Cbl-b. 2014 Jul 2
5 24886428 A PKC-SHP1 signaling axis desensitizes Fcγ receptor signaling by reducing the tyrosine phosphorylation of CBL and regulates FcγR mediated phagocytosis. 2014 May 7 2
6 24994594 Loss of Cbl-PI3K interaction in mice prevents significant bone loss following ovariectomy. 2014 Oct 1
7 23127761 Casitas B-lineage lymphoma mutants activate AKT to induce transformation in cooperation with class III receptor tyrosine kinases. 2013 Mar 1
8 23216754 The proline-rich tyrosine kinase Pyk2 regulates platelet integrin αIIbβ3 outside-in signaling. 2013 Feb 2
9 21041311 A CSF-1 receptor phosphotyrosine 559 signaling pathway regulates receptor ubiquitination and tyrosine phosphorylation. 2011 Jan 14 5
10 21242968 c-Cbl inhibits angiogenesis and tumor growth by suppressing activation of PLCγ1. 2011 May 12 1
11 21708930 CIN85 drives B cell responses by linking BCR signals to the canonical NF-kappaB pathway. 2011 Jul 4 1
12 21952831 Abrogation of Cbl-PI3K interaction increases bone formation and osteoblast proliferation. 2011 Nov 1
13 21967979 Tyrosine phosphorylated c-Cbl regulates platelet functional responses mediated by outside-in signaling. 2011 Nov 17 1
14 19966856 Differential subcellular localization regulates c-Cbl E3 ligase activity upon Notch3 protein in T-cell leukemia. 2010 Mar 11 1
15 20133944 c-Cbl promotes T cell receptor-induced thymocyte apoptosis by activating the phosphatidylinositol 3-kinase/Akt pathway. 2010 Apr 2 3
16 20592236 Role of c-Cbl-dependent regulation of phospholipase Cgamma1 activation in experimental choroidal neovascularization. 2010 Dec 1
17 20851882 The loss of Cbl-phosphatidylinositol 3-kinase interaction perturbs RANKL-mediated signaling, inhibiting bone resorption and promoting osteoclast survival. 2010 Nov 19 2
18 19074136 Cbl enforces an SLP76-dependent signaling pathway for T cell differentiation. 2009 Feb 13 1
19 19909244 A role for protein ubiquitination in VEGFR-2 signalling and angiogenesis. 2009 Dec 1
20 18482989 Control of T lymphocyte signaling by Ly108, a signaling lymphocytic activation molecule family receptor implicated in autoimmunity. 2008 Jul 11 1
21 17202354 Redundancy in B cell developmental pathways: c-Cbl inactivation rescues early B cell development through a B cell linker protein-independent pathway. 2007 Jan 15 1
22 17446348 Flt3-dependent transformation by inactivating c-Cbl mutations in AML. 2007 Aug 1 1
23 16262245 Requirement of SRC-family tyrosine kinases in fat accumulation. 2005 Nov 8 1
24 15001553 The c-Cbl/CD2AP complex regulates VEGF-induced endocytosis and degradation of Flt-1 (VEGFR-1). 2004 May 1
25 15297464 A juxtamembrane tyrosine in the colony stimulating factor-1 receptor regulates ligand-induced Src association, receptor kinase function, and down-regulation. 2004 Oct 15 1
26 12591907 A mouse with a loss-of-function mutation in the c-Cbl TKB domain shows perturbed thymocyte signaling without enhancing the activity of the ZAP-70 tyrosine kinase. 2003 Feb 17 1
27 12642595 Growth hormone-induced phosphorylation of epidermal growth factor (EGF) receptor in 3T3-F442A cells. Modulation of EGF-induced trafficking and signaling. 2003 May 23 1
28 12652654 Expression and tyrosine phosphorylation of Cbl regulates macrophage chemokinetic and chemotactic movement. 2003 May 1
29 12959979 Distinct roles of p130Cas and c-Cbl in adhesion-induced or macrophage colony-stimulating factor-mediated signaling pathways in prefusion osteoclasts. 2003 Nov 2
30 14627991 Serine mutations that abrogate ligand-induced ubiquitination and internalization of the EGF receptor do not affect c-Cbl association with the receptor. 2003 Nov 20 1
31 14629478 c-Cbl negatively regulates platelet activation by glycoprotein VI. 2003 Nov 1
32 14654781 c-CBL is not required for leukemia induction by Bcr-Abl in mice. 2003 Dec 4 1
33 11896602 Membrane-anchored Cbl suppresses Hck protein-tyrosine kinase mediated cellular transformation. 2002 Mar 7 1
34 11997497 APS facilitates c-Cbl tyrosine phosphorylation and GLUT4 translocation in response to insulin in 3T3-L1 adipocytes. 2002 Jun 9
35 12032836 Isolation and characterization of a novel, transforming allele of the c-Cbl proto-oncogene from a murine macrophage cell line. 2002 May 23 1
36 12061819 EGF-dependent association of phospholipase C-gamma1 with c-Cbl. 2002 Jul 1 2
37 12193575 c-Cbl is a negative regulator of GH-stimulated STAT5-mediated transcription. 2002 Sep 2
38 11313921 c-Cbl facilitates fibronectin matrix production by v-Abl-transformed NIH3T3 cells via activation of small GTPases. 2001 Mar 29 3
39 11342532 Potentiation of insulin-related signal transduction by a novel protein-tyrosine phosphatase inhibitor, Et-3,4-dephostatin, on cultured 3T3-L1 adipocytes. 2001 Jul 20 1
40 11443118 CrkL is recruited through its SH2 domain to the erythropoietin receptor and plays a role in Lyn-mediated receptor signaling. 2001 Aug 31 1
41 11514605 T cell development and T cell responses in mice with mutations affecting tyrosines 292 or 315 of the ZAP-70 protein tyrosine kinase. 2001 Aug 20 1
42 10684856 Cbl suppresses B cell receptor-mediated phospholipase C (PLC)-gamma2 activation by regulating B cell linker protein-PLC-gamma2 binding. 2000 Feb 21 1
43 10799548 Hck enhances the adherence of lipopolysaccharide-stimulated macrophages via Cbl and phosphatidylinositol 3-kinase. 2000 May 12 2
44 10861086 Differential involvement of Src family kinases in Fc gamma receptor-mediated phagocytosis. 2000 Jul 1 1
45 10979970 Reduced oncogenicity of p190 Bcr/Abl F-actin-binding domain mutants. 2000 Sep 15 1
46 11021752 Constitutive activation of FLT3 stimulates multiple intracellular signal transducers and results in transformation. 2000 Oct 1
47 11069064 Activation of the Ras-related GTPase Rap1 by thymocyte TCR engagement and during selection. 2000 Oct 1
48 9973464 CD38-mediated signaling events in murine pro-B cells expressing human CD38 with or without its cytoplasmic domain. 1999 Feb 15 1
49 10092522 The proto-oncogene p120(Cbl) is a downstream substrate of the Hck protein-tyrosine kinase. 1999 Apr 2 2
50 10347229 Cbl-mediated negative regulation of platelet-derived growth factor receptor-dependent cell proliferation. A critical role for Cbl tyrosine kinase-binding domain. 1999 Jun 4 2