Gefitinib

transforming growth factor alpha ; Homo sapiens







13 Article(s)
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1 32169452 Fucoidan increased the sensitivity to gefitinib in lung cancer cells correlates with reduction of TGFβ-mediated Slug expression. 2020 Jun 15 3
2 31670920 EGFR is a Therapeutic Target in Hormone Receptor-Positive Breast Cancer. 2019 1
3 29467862 Lentivirus-mediated silencing of HOTAIR lncRNA restores gefitinib sensitivity by activating Bax/Caspase-3 and suppressing TGF-α/EGFR signaling in lung adenocarcinoma. 2018 Mar 1
4 24486412 Upregulation of HIF-2α induced by sorafenib contributes to the resistance by activating the TGF-α/EGFR pathway in hepatocellular carcinoma cells. 2014 May 1
5 23608755 Transforming growth factor-α activates pancreatic stellate cells and may be involved in matrix metalloproteinase-1 upregulation. 2013 Jun 1
6 22863020 Hypoxia induces gefitinib resistance in non-small-cell lung cancer with both mutant and wild-type epidermal growth factor receptors. 2012 Nov 3
7 21382168 Transforming growth factor-α attenuates hepatic fibrosis: possible involvement of matrix metalloproteinase-1. 2011 Apr 1
8 18811692 Clinical significance of pretreatment serum amphiregulin and transforming growth factor-alpha, and an epidermal growth factor receptor somatic mutation in patients with advanced non-squamous, non-small cell lung cancer. 2008 Nov 1
9 16568376 Gefitinib and the modulation of the signaling pathways downstream of epidermal growth factor receptor in human liver cancer cells. 2006 Feb 7
10 16585207 Transforming growth factor alpha expression drives constitutive epidermal growth factor receptor pathway activation and sensitivity to gefitinib (Iressa) in human pancreatic cancer cell lines. 2006 Apr 1 4
11 16685431 Canonical WNT signaling pathway and human AREG. 2006 Jun 1
12 16230376 Increases of amphiregulin and transforming growth factor-alpha in serum as predictors of poor response to gefitinib among patients with advanced non-small cell lung cancers. 2005 Oct 15 5
13 15387370 Tamoxifen resistance in breast cancer cells is accompanied by an enhanced motile and invasive phenotype: inhibition by gefitinib ('Iressa', ZD1839). 2004 1